Gerontology News and Research

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Gerontology is the study of the social, psychological and biological aspects of aging.

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

2 Jun 2023

Study Offers New Insight into the Kinetics of Prostatic Inflammaging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate."

24 May 2023

Study Offers New Insights Into Neuroendocrine Transdifferentiation in Breast and Prostate Cancer Biology

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation."

15 May 2023

Multi-Angled Approach of Identifying Dual-Purpose Therapeutic Targets Implicated in Aging, Glioblastoma

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform."

3 May 2023

First Chronic Wound Murine Model to Profile the Effects of Cellular Senescence

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "A chronic wound model to investigate skin cellular senescence."

2 May 2023

Inhibition of p21 may be a Promising Strategy for Limiting Age-Related Inflammatory Disorders

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 7, entitled, "p21 facilitates chronic lung inflammation via epithelial and endothelial cells."

18 Apr 2023

MET+LEU Cocktail Prevents Cellular Senescence and Disrupted Proteostasis Induced by Myotube Atrophy

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 6, entitled, "Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail."

3 Apr 2023

Age-related sarcopenia prevented by AAV1.NT-3 gene therapy

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "AAV1.NT-3 gene therapy prevents age-related sarcopenia."

16 Mar 2023

Study: Platelets likely to perform a protective function in AD

A new research paper was published on the cover of Aging entitled, "Immune-mediated platelet depletion augments Alzheimer's disease neuropathological hallmarks in APP-PS1 mice."

16 Feb 2023

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 2, entitled, "Clearance of p16Ink4a-positive cells in a mouse transgenic model does not change β-cell mass and has limited effects on their proliferative capacity."

1 Feb 2023

Role of adolescent lifestyle in biological aging

According to findings published in eLife, genetics may contribute to the explanation of the connection between unhealthy lifestyles and increased biological aging in young adults.

10 Nov 2022

Gut microbiome’s influence on how lifestyle affects dementia risk

A recent Baycrest study points to the possibility that the gut microbiome influences how nutrition and exercise impact brain health and dementia risk. Physicians and researchers could be able to improve dementia prevention efforts with the use of this knowledge.

13 Oct 2022

Genetic variations in key mitochondrial enzyme associated with age-related mobility changes

Age-related changes in strength and mobility may depend on genetic variations in a critical mitochondrial enzyme, suggests a study published today in eLife.

27 Apr 2022

Newborn cells in patients with epilepsy, likely to provide a potential treatment

According to a study headed by researchers from USC Stem Cell and the USC Neurorestoration Center, adults may recover at least some of what they have lost by producing new brain cells, and this process is profoundly modified in patients with long-term epilepsy.

7 Apr 2022

Gerontology News and Research

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

Study Offers New Insight into the Kinetics of Prostatic Inflammaging

Study Offers New Insights Into Neuroendocrine Transdifferentiation in Breast and Prostate Cancer Biology

Multi-Angled Approach of Identifying Dual-Purpose Therapeutic Targets Implicated in Aging, Glioblastoma

First Chronic Wound Murine Model to Profile the Effects of Cellular Senescence

Inhibition of p21 may be a Promising Strategy for Limiting Age-Related Inflammatory Disorders

MET+LEU Cocktail Prevents Cellular Senescence and Disrupted Proteostasis Induced by Myotube Atrophy

Age-related sarcopenia prevented by AAV1.NT-3 gene therapy

Study: Platelets likely to perform a protective function in AD

Deletion of p16Ink4a cells does not negatively impact β-cell mass and proliferation in mice

Role of adolescent lifestyle in biological aging

Gut microbiome’s influence on how lifestyle affects dementia risk

Genetic variations in key mitochondrial enzyme associated with age-related mobility changes

Newborn cells in patients with epilepsy, likely to provide a potential treatment

Lifelong exercise may help counteract the deterioration of fat tissue function with age

Researchers identify toxic senescent cells in the brain as potential target for Alzheimer’s treatment

Green tea catechins extend the lifespan of C. elegans

Using a new genetic technology to decipher intratumoral heterogeneity

Study shows that neural stem cells age quickly

Food choice may accelerate aging and shorten lifespan of fruit flies

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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