Ligase News and Research

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SDIR1 enzyme plays a major role in the expression of defense gene in plants

A new study offers evidence that microbes are trying to hijack the plant immune system to induce disease while also offering insights into a new mechanism.

26 Apr 2021

Absence of TRIM37 protein boosts genetic instability in patients with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

1 Mar 2021

Study reveals new gene involved in motor neuron diseases

According to a study, failures in a quality control system that defends protein-building fidelity in cells can result in motor neuron degeneration.

18 Sep 2020

Scientists develop CRISPR-assisted method to detect RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

2 Jul 2020

‘Terminator’ protein halts tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

4 Jun 2020

Novel mechanism allows the immune system to control autoimmunity, cancer

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) revealed a novel mechanism through which the immune system can control autoimmunity and cancer.

7 May 2020