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Understanding How Tumor-Derived Extracellular Vesicles Enter Target Cells

Most cells in the body send out little messengers called extracellular vesicles that carry proteins, lipids, and other bioactive molecules to other cells, playing an important role in intercellular communication.

17 Mar 2025

Stanford Researchers Find a Molecule That Rivals Ozempic in Weight Loss

BRP emerges as a promising peptide for weight loss, activating appetite control pathways without triggering nausea, paving the way for safer obesity therapies.

17 Mar 2025

SRS Microscopy Unlocks New Insights into Cellular Metabolism and Disease

Cellular metabolism plays a critical role in various physiological and pathological processes. High resolution imaging of intracellular metabolic activities is crucial for understanding many biological pathways, and for facilitating disease prognosis and treatment assessment.

14 Mar 2025

Molecular Intelligence Simplifies Cryo-EM Data Analysis with AI

Scientists from Purdue University’s College of Science and the Rosen Center for Advanced Computing have established Molecular Intelligence, a software company dedicated to assisting researchers in determining the 3D structures of biomolecules captured through cryogenic-electron microscopy (cryo-EM).

13 Mar 2025

Novel Tool Uses DNA Barcode System for Deep-Tissue RNA and Protein Imaging

For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the genome controls development and needed to image hundreds of RNA molecules in a thick tissue sample to understand where and how genes were being expressed in cells.

13 Mar 2025

Cryo-EM Reveals 3D Structure of Nipah Virus RNA Polymerase

The replication of the Nipah virus's genetic material in infected cells has been demonstrated for the first time by researchers from the Max Planck Institute (MPI) for Multidisciplinary Sciences and the University Medical Center Göttingen (UMG). In humans, the virus can cause fatal encephalitis.

11 Mar 2025

Low-Cost, Flexible Protein Detection Platform for Global Health

Chemical and biomolecular engineers at Georgia Tech have created a plug-and-play platform for the detection of disease protein biomarkers that is straightforward, adaptable, and user-friendly, eliminating the need for expensive laboratory equipment.

10 Mar 2025

Novel Enzyme for Synthesizing β-1,2-Galactooligosaccharides

Carbohydrate chains, also known as glycans, are intricate sugar-like molecules that are crucial for various biological functions and structures within human bodies.

7 Mar 2025

Neural Mechanism Involved in Leptin Resistance Revealed

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category.

5 Mar 2025

Unlocking the Secrets of Fertilization Inhibition

A research team headed by Yale scientists has elucidated the workings of a natural biological process that blocks the interaction between sperm and egg, thus inhibiting fertilization.

4 Mar 2025

Breakthrough Fluorescent Dye Sets New Standard for Long-Term Cellular Imaging

A research team at POSTECH (Pohang University of Science and Technology) has successfully developed a super-photostable organic dye after two years of dedicated research-demonstrating perseverance akin to that of Marie Curie, who painstakingly extracted just 0.1 grams of radium from eight tons of ore to earn her Nobel Prize.

28 Feb 2025

Unveiling the Role of NUDIX Hydrolase in Fungal Infection

Researchers from The Australian National University (ANU), in partnership with scientists from Germany and the United States, have identified a potent “weapon” employed by numerous pathogenic fungi to infect staple food crops like rice and corn. This discovery may lead to novel approaches for enhancing global food security.

28 Feb 2025

New Lipid Nanoparticles Deliver mRNA for Lung Tissue Regeneration

New research from the Perelman School of Medicine at the University of Pennsylvania suggests that a combination of messenger RNA (mRNA) and a novel lipid nanoparticle (LNP) could potentially be used to repair lung damage.

24 Feb 2025

New Microscope Captures Full 3D Molecular Dynamics

When two instruments are cleverly recombined, they can sometimes achieve things that neither instrument could have done alone.

24 Feb 2025

Novel Catalysis Yields Elusive Fluorinated Oxetanes for Drug Discovery

Researchers at the National University of Singapore have developed a groundbreaking catalytic process that transforms epoxides into fluorinated oxetanes.

24 Feb 2025

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

22 Feb 2025

LUC7 Proteins Play Key Role in RNA Splicing Control

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025