Neurodegenerative Diseases News and Research

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Scientists Discover Surprising Directional Flexibility in DNA-Shaping Motors

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction.

17 Jan 2025

Weak Molecular Interactions Trigger Autophagy in Cells

Recycling takes place in our cells at all times: in a process called autophagy, cell components that are no longer needed are enclosed by membranes and broken down into their basic building blocks.

8 Jan 2025

Researchers Discover Genetic Markers for PFAS-Induced Neurotoxicity

Per- and polyfluorinated alkyl substances (PFAS) earn their "forever chemical" moniker by persisting in water, soil and even the human brain.

7 Jan 2025

Ancient DNA Analysis Unveils Migration Patterns in Early Europe

Waves of human migration across Europe during the first millennium AD have been revealed using a more precise method of analyzing ancestry with ancient DNA, in research led by the Francis Crick Institute.

2 Jan 2025

Uncovering the Cellular Mechanisms of Brain Aging

Not all brain cell types age in the same way, according to new brain mapping research supported by the National Institutes of Health (NIH).

2 Jan 2025

Research Reveals Regulatory Role of Glucose-6-Phosphate Dehydrogenase in Mitophagy

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway.

30 Dec 2024

Chaperone Proteins Unveil Their Role in Neurotransmission

A team of researchers from the University of Massachusetts Amherst is the first to show how proteins called "chaperones" are vital in ensuring that neurons can transmit signals to one another. When this neurotransmission breaks down, devastating diseases such as Alzheimer's and Parkinson's along with many others, can occur.

19 Dec 2024

Insights into Neurodegenerative Diseases and Pest Control

Key gene regulators that allow certain deafened animals, such as fish and lizards, to naturally regenerate their hearing have been identified by a recent USC Stem Cell study that was published in the journal Proceedings of the National Academy of Sciences (PNAS).

10 Dec 2024

New Brain Mapping Reveals Connections Behind Higher Order Functions

A new way of mapping activity and connections between different regions of the brain has revealed fresh insights into how higher order functions like language, thought and attention, are organized.

9 Dec 2024

New Discovery Redefines the Shape of Axons in Mammalian Brain Cells

Biology textbooks may need a revision, say Johns Hopkins Medicine scientists, who present new evidence that an armlike structure of mammalian brain cells may be a different shape than scientists have assumed for more than a century.

3 Dec 2024

Mathematical Approach Helps Understand Complex Neural Systems

In an article published in the scientific journal PNAS Nexus, researchers from the Neuromorphic Engineering Laboratory at the University of Liège reveal a fascinating brain mechanism: the ability of neurons to maintain reliable functions despite significant variability in their physiological components.

29 Nov 2024

Advanced Sequencing Uncovers Cause of Rare Mitochondrial Encephalopathy

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 births.

19 Nov 2024

New Mechanism for Precise Protein Production Unveiled

A new process that is essential to the synthesis of cellular proteins has been discovered by an international research team.

15 Nov 2024

Novel Approach to Combat Protein-Related Diseases

Researchers from Mainz and Leiden universities have devised a simple model system that can be used to break down fibrils, the cause of several diseases like Alzheimer's and Parkinson's disease, into their constituent single units or liquid droplets.

14 Nov 2024

How Neuroimmune Cells Modulate Immune Responses and Neuroinflammation

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system.

7 Nov 2024

A New Statistical Method to Mitigate AI Bias in Genetic Research

Researchers at the University of Wisconsin–Madison are cautioning that the growing use of artificial intelligence techniques in genetics and medicine may result in incorrect inferences regarding the relationship between genes and physical traits, such as risk factors for diseases like diabetes.

5 Nov 2024