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Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

Research identifies two states of age-associated thymic epithelial cells, linking thymic degeneration to aging and injury, impacting immune system function.

26 Aug 2024

Discovery of Novel Macrophage Population Offers Hope for Lung Repair Post-Viral Infection

Researchers at the University of Liège (Belgium) have discovered a new population of macrophages, important innate immune cells that populate the lungs after injury caused by respiratory viruses.

5 Aug 2024

Study Reveals Widespread Gene Misbehavior in Healthy Humans

Scientists have uncovered that ‘gene misbehaviour’ – where genes are active when they were expected to be switched off – is a surprisingly common phenomenon in the healthy human population.

29 Jul 2024

New Insights into the Mechanisms of Gene Misbehavior

Researchers have discovered that a startlingly widespread occurrence in the healthy human population is "gene misbehavior," or the state in which genes are active when they should be inactive.

25 Jul 2024

New RNA Sequencing Dataset Reveals Genetic Diversity Across Global Populations

An open-access dataset of RNA sequences from lymphoblastoid cell lines of 731 individuals spanning 26 populations and five continental groups.

24 Jul 2024

Study Identifies Microproteins as Key Source of Tumor-Specific Antigens in Liver Cancer

If microproteins translated from noncanonical open reading frames (ncORFS) in long noncoding ribonucleic acids (RNAs) could be a potential source of tumor-specific antigens.

23 Jul 2024

Unveiling IRF1's Influence on Cancer Progression and Treatment Using Histology and Flow Cytometry

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have discovered new information regarding the function of a protein known as interferon regulatory factor (IRF1) in the course of cancer and how it responds to treatment. This information may help increase the efficacy of cancer immunotherapy.

16 Jul 2024

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Study Highlights MSC-EVs Potential for Alleviating Lung Fibrosis

Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by fibroblast proliferation and extracellular matrix formation, causing structural damage and lung failure.

27 Jun 2024

Detecting Auto-Antibodies for Early Identification of High-Risk COVID-19 Cases

Researchers recently discovered that auto-antibodies against their type 1 interferons, crucial immunological signaling proteins, were present in some COVID-19 patients.

20 Jun 2024

Innovative ssREAD Database Provides Rich Alzheimer's Disease RNA-Seq Resources for Researchers

The Single-cell and Spatial RNA-seq databasE for Alzheimer’s Disease, or ssREAD.

12 Jun 2024

Innovative Gene Editing Elevates Photosynthetic Efficiency in Food Crops

A team from the Innovative Genomics Institute at the University of California, Berkeley (UCB) has produced an increase in gene expression in a food crop by changing its upstream regulatory DNA.

10 Jun 2024

New research identifies and mitigates bias in CRISPR-Cas9 gene editing

A phenomics approach to study proximity bias and the unrelated chromosomal truncations.

10 Jun 2024

Multiciliated Cell Differentiation Regulated by an Alternative Cell Cycle

A fertilized egg can develop into a baby through the amazing process of cell division, while a malignant cell can become a malignant tumor. Since there is so much on the line, nature maintains strict control over it through a mechanism known as the cell cycle that scientists once believed they thoroughly understood.

7 Jun 2024

Columbia Studies Uncover Misidentification of Gut Stem Cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

7 Jun 2024

Newly Discovered CD8-fit Cells Could Revolutionize Cancer Treatment

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

30 May 2024

Unlocking the Power of Circadian Rhythms for Enhancing Cancer Immunotherapy

A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy.

29 May 2024