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New insight into how immune systems of stickleback fish respond to tapeworm parasite

Lugging around a tapeworm that's one third your body weight can be a real drag. So threespine stickleback fish evolved resistance to tapeworms-;but resistance has costs of its own, a team of researchers show in Science on 8 September.

9 Sep 2022

Research highlights the new genetic variations and pediatric NAFLD severity

A multidisciplinary group of researchers at the University of California San Diego School of Medicine have advanced investigations into the genetic causes of NAFLD in children.

1 Jul 2022

Cell-derived therapy may help treat ventricular arrhythmia

Vesicles secreted from human heart cells may repair damaged tissue and prevent lethal heart rhythm disorders, according to a new study from investigators in the Smidt Heart Institute at Cedars-Sinai.

13 Apr 2022

Threespine stickleback fish study details how parasite resistance in hosts arises

They thrive everywhere from bustling cities to remote rainforests -; even in our own backyards. Pervasive and unapologetic mooches, parasites rely on other organisms for their survival.

3 Mar 2022

Severe lung injuries can trigger stem cells to undergo abnormal differentiation, study finds

Severe injuries to the lung from diseases such as COVID-19 trigger abnormal stem cell repair that alters the architecture of the lung. The aberrant stem cell differentiation in response to injury can prevent the restoration of normal lung function.

31 Dec 2021

Researchers regenerate cartilage using novel protein fragment

The existing methods for the regeneration of injured cartilage generate tissue that breaks down. This deterioration eventually leads to osteoarthritis—the commonly seen form of arthritis—affecting over 32.5 million grown-ups in the United States, as per the Centers for Disease Control and Prevention.

13 Dec 2021

Researchers develop new technique to print tri-layered skin equivalents

Chronic wounds are deep and difficult to repair. Often, the top of the injury heals before the bottom, so the wound collapses in on itself. Over time, this can result in scar tissue and reduced skin function.

6 Dec 2021

Researchers discover a link between genetic variant and chronic hypersensitivity pneumonitis

Chronic hypersensitivity pneumonitis (CHP) is a long-term lung condition where the interstitial tissue surrounding the alveoli (air sacs) of the lungs becomes inflamed and develops "fibrosis", or scar tissue.

17 Nov 2021

Radiation therapy can reprogram heart muscle cells to a younger state, suggests study

New research from Washington University School of Medicine in St. Louis suggests that radiation therapy can reprogram heart muscle cells to what appears to be a younger state, fixing electrical problems that cause a life-threatening arrhythmia without the need for a long-used, invasive procedure.

27 Sep 2021

Scientists analyze the molecular machinery of poxviruses at an atomic level

Poxviruses have found a unique way of translating their genes into proteins in the infected organism. A team of researchers from Würzburg shows for the first time how the molecular machinery involved works at an atomic level.

24 Sep 2021

Stem cell transplantation leaves no scars in the DNA of transplanted cells

Stem cell transplants do not lead to changes in the DNA of the donor cells. That's according to a new study, which provides important evidence for the safety of this procedure.

8 Sep 2021

Stiffness of protein fibers plays a key role in controlling cell movement, study shows

A new study, led by University of Minnesota Twin Cities engineering researchers, shows that the stiffness of protein fibers in tissues, like collagen, are a key component in controlling the movement of cells.

23 Jul 2021

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Liver fibrosis might be treatable with selective immunotoxins

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

13 Jul 2021

Single mutation leads to rare genetic muscle disease

The origin of rare, severe muscle disease has been uncovered by an international team of researchers headed by the University of Bonn (Germany).

16 Jun 2021

Study shows how scar tissue can effectively regenerate the injured heart

It is estimated that during a heart attack, one billion cells in the heart are lost. In the wake of the heart attack, the lost tissue is replaced by scar tissue, which can lead to heart failure, arrhythmia and death. In a new study, researchers from the University of Tsukuba have shown how cells in the scar tissue can be converted to heart muscle cells, effectively regenerating the injured heart.

3 Jun 2021

3D biomaterial helps implanted stem cells stick around to reverse arthritis

A 3D biomaterial scaffold design to slowly release stem cells has worked to ensure implanted stem cells stick around to relieve pain and reverse arthritis in mice knee joints.

19 Apr 2021

Neurod4 gene found to be the key factor in nerve regeneration after spinal cord injury

Nagoya University researchers have identified a gene that plays a crucial role in regenerating neurons of African clawed frog tadpoles, which has an unusually high capacity for nerve regeneration.

31 Mar 2021

Early exposure to tough conditions could impact oysters' ability to grow meaty tissue

Early exposure to tough conditions--particularly warmer waters and nightly swings of low oxygen--could leave lasting scars on oysters' ability to grow meaty tissue.

2 Mar 2021

Study shows two phases of wall restructuring after an aneurysm forms

Hitting a pothole on the road in just the wrong way might create a bulge on the tire, a weakened spot that will almost certainly lead to an eventual flat tire. But what if that tire could immediately begin reknitting its rubber, reinforcing the bulge and preventing it from bursting?

27 Jan 2021