Sepsis News and Research

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Sepsis is a life-threatening illness. Your body's response to a bacterial infection usually causes it. Your immune system goes into overdrive, overwhelming normal processes in your blood. The result is that small blood clots form, blocking blood flow to vital organs. This can lead to organ failure. Babies, old people and those with weakened immune systems are most likely to get sepsis. But even healthy people can become deathly ill from it.

New solution to treat diseases caused by exaggerated inflammation

A recent study guided by the Instituto Gulbenkian de Ciência (IGC) shows how anticancer drugs reduce inflammation, establishing them as prospective sepsis treatments.

11 Jan 2023

New drug to tackle complex cases of UTI

A new drug combination has been shown to be more successful, especially against persistent, drug-resistant infections, according to an international study conducted by a Rutgers Researcher comparing new and older therapies for complex urinary tract infections.

From Rutgers University 28 Oct 2022

Hydroquinine inhibits and kills several strains of clinically important bacteria

A naturally occurring substance known as hydroquinine has been discovered by researchers to have bacterial killing ability against a variety of pathogens.

2 Sep 2022

Researchers discover a way for detecting resistance-encoding genes in bacteria

Chalmers University of Technology researchers have devised a method for detecting certain bacterial genes that encode resistance using conventional microscopes, which are already used to diagnose TB in low-income countries.

27 Jun 2022

Novel insights into how some bacteria evade antibiotics

Scientists have revealed how antibiotics can regress certain fast-growing bacteria. The research was published in the journal eLife on June 8th, 2022.

8 Jun 2022

Immune-boosting drugs with antibiotics may reduce the health risks of fungal infections

Patients are more susceptible to fungal infections because the immune system in the gut is disrupted when patients are given antibiotics in the hospital.

18 May 2022

Study addresses genetic diversity of Clostridioides difficile using systems biology technique

Researchers from Jacobs School of Engineering and the University of California San Diego School of Medicine collaborated with colleagues from Baylor College of Medicine to decode the genetic diversity of Clostridioides difficile, an especially dangerous pathogen in healthcare settings, using a systems biology technique.

29 Apr 2022

New automated system behaves as a promising tool to treat human bloodstream infections

When treating patients with acute infections, healthcare professionals must be able to quickly and properly determine which antibiotics are most effective in combating the disease.

20 Apr 2022

Tuberculosis causes early epigenetic aging in cells, study finds

In the current study, scientists at Baylor College of Medicine identified that the cells of humans and animals that recovered from tuberculosis had prematurely aged up to 12 to 14 years.

25 Mar 2022

Study reveals novel mechanism used by infectious bacteria to survive stressful situations

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections-;such as urinary tract and bloodstream infections like sepsis- are hard to get rid of.

From The University of Utah 24 Mar 2022

Discovery provides new insights into the understanding of tolerance to endotoxic death

Sepsis is a high-mortality disease that arises when the body's immune reaction to pathogens causes multi-organ defects.

9 Mar 2022

Study provides insights into the biological mechanisms behind the severe form of COVID-19

A total of 16 novel genetic variations linked to severe Covid-19 have been discovered, including ones that affect blood coagulation, immunological response, and inflammation severity.

8 Mar 2022

Researchers study the impact of broad-spectrum antibiotics on the infants’ microbiome

A recent study proves that antibiotic use in the first week of birth is associated with a reduction in the number of healthy bacteria required to digest milk.

22 Feb 2022

Discovery of chiral evasion could lead to more resilient inhibitors, better drug designs

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial infection that has become resistant to most of the antibiotics used to treat regular staph infections.

18 Feb 2022

One-time infusion of stem cells from bone marrow improves sepsis survival in mice

A one-time infusion of stem cells from bone marrow improves the survival of mice with sepsis, shows a study published today in eLife.

16 Feb 2022

Scientists discover “resistance gene” in harmful E. coli bacteria

Researchers have discovered a gene that makes E. coli bacteria resistant to antibiotics, effectively leading to better treatment for people across the globe.

20 Jan 2022

Pyroptosis is not a one-way ticket, it can be halted and controlled

A study published by researchers at the University of Illinois Chicago describes a new method for analyzing pyroptosis -; the process of cell death that is usually caused by infections and results in excess inflammation in the body -; and shows that process, long thought to be irreversible once initiated, can in fact be halted and controlled.

11 Jan 2022