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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Astrocyte Receptor Effects Differ Dramatically Between Sexes

Weill Cornell Medicine scientists have uncovered the first evidence that astrocyte receptors can trigger opposite effects on cognitive function in male and female preclinical models.

31 May 2024

C. elegans Study Reveals Impact of Embryonal Amphetamine Exposure

Amphetamine is a psychostimulant that has been used to treat a variety of brain dysfunctions. However, it is a highly abused drug.

31 May 2024

Protein Imbalance Linked to Rare Developmental Disorder

According to a recent study from the University of Lausanne, serious intellectual impairments can result from both an excess or a shortage of a single protein.

31 May 2024

Efficient Gene Editing with Compact Cas12a Protein

Researchers have created an innovative version of a critical CRISPR gene-editing protein that has effective editing activity and is small enough to be bundled into a non-pathogenic virus capable of delivering it to targeted cells.

31 May 2024

Engineered DNA PROTAC Shows Promise for p53-R175H Mutant Cancers

A synthetic bicomponent compound specifically targets and eliminates a mutant protein associated with multiple forms of cancer.

30 May 2024

Structural Insights into a Novel Gene-Editing Tool

Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo conducted collaborative research to ascertain the spatial organization of different processes within a unique gene-editing instrument known as “prime editor.”

30 May 2024

Inverse relationship found between anti-inflammatory macrophages and NK cells/T cells in lung cancer

Single-cell ribonucleic acid sequencing (scRNAseq) and spatial transcriptomics to study cellular organization and interactions within the tumor microenvironment.

30 May 2024

Revolutionizing Cell Subpopulation Studies: The ConVERGD Approach

As gene sequencing technologies become more powerful, our understanding of cellular diversity has grown in parallel.

29 May 2024

Understanding the Genetic Basis of Tea Aroma with Lipidomics and Hormone Profiling

The journey from tea leaf to infusion is a complex one, with a multitude of factors influencing the final taste and aroma.

28 May 2024

Snail Research Reveals the Adaptation of Biological Clocks to Tidal Environments

Organisms, including humans, follow a schedule that coordinates important bodily functions such as sleep-wake cycles, metabolism, hormone production, cognitive function, and feeding habits to environmental cycles.

28 May 2024

Deciphering the Genetic Basis of Bayberry Fruit Quality

The Chinese bayberry, Myrica rubra, is a subtropical fruit highly valued for its distinctive flavor, nutritional benefits, and economic importance.

28 May 2024

Modifying Cellular Interactions Near Amyloid Plaques May Offer New Alzheimer's Treatments

Researchers at Mount Sinai’s Icahn School of Medicine have achieved a big breakthrough in Alzheimer’s disease research by discovering a new technique to potentially slow or even stop disease development.

28 May 2024

Integrative genomic study identifies two new potential drug targets in Mycobacterium tuberculosis

Researchers used existing whole genome sequences of M. tuberculosis and conducted a pangenomic analysis to identify potential drug targets.

28 May 2024

Study Reveals Allele-Specific DNA Methylation in Hybrid Poplar Regeneration

Understanding plant regeneration at the molecular level is pivotal for advancements in genetic transformation and genome editing.

27 May 2024

CRISPR Screening Reveals Peptide in Human RNA Regulating Inflammation

UC Santa Cruz researchers have discovered a peptide in human RNA that regulates inflammation and may provide a new path for treating diseases such as arthritis and lupus.

27 May 2024

Comprehensive Analysis of Gene-Isoform Variation Unlocks Secrets of Brain Development

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

24 May 2024

SPT Labtech’s Firefly® Liquid Handler Chosen by Colossal Biosciences to Accelerate NGS Capabilities in Fight Against Species Extinction and Biodiversity Loss

SPT Labtech, a global leader in the design, development and manufacture of automated instrumentation and consumables for life science applications, announces that its firefly liquid handling platform has been selected by Colossal Biosciences to enhance its Next Generation Sequencing (NGS) capabilities.

From SPT Labtech 24 May 2024

Cryo-EM Study Reveals Cas7-11-CRISPR Complex Regulation Mechanisms

In a recent study published in Signal Transduction and Targeted Therapy, Chinese researchers studied the cryo-electron microscopy structures of the CRISPR-Cas7-11 nuclease, both alone and in complex with the regulatory protein tetratricopeptide repeat fused with Cas/(human enhancer of filamentation 1) HEF1-associated signal transducer (TPR-CHAT).

24 May 2024

New Chemical Modification Enhances Antisense Oligonucleotide Targeting in CNS Diseases

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians alike.

23 May 2024

Multiplexed Orthogonal Base Editors for Precise Mutation Modeling

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup.

23 May 2024

Gene News and Research

Further Reading

Astrocyte Receptor Effects Differ Dramatically Between Sexes

C. elegans Study Reveals Impact of Embryonal Amphetamine Exposure

Protein Imbalance Linked to Rare Developmental Disorder

Efficient Gene Editing with Compact Cas12a Protein

Engineered DNA PROTAC Shows Promise for p53-R175H Mutant Cancers

Structural Insights into a Novel Gene-Editing Tool

Inverse relationship found between anti-inflammatory macrophages and NK cells/T cells in lung cancer

Revolutionizing Cell Subpopulation Studies: The ConVERGD Approach

Understanding the Genetic Basis of Tea Aroma with Lipidomics and Hormone Profiling

Snail Research Reveals the Adaptation of Biological Clocks to Tidal Environments

Deciphering the Genetic Basis of Bayberry Fruit Quality

Modifying Cellular Interactions Near Amyloid Plaques May Offer New Alzheimer's Treatments

Integrative genomic study identifies two new potential drug targets in Mycobacterium tuberculosis

Study Reveals Allele-Specific DNA Methylation in Hybrid Poplar Regeneration

CRISPR Screening Reveals Peptide in Human RNA Regulating Inflammation

Comprehensive Analysis of Gene-Isoform Variation Unlocks Secrets of Brain Development

SPT Labtech’s Firefly® Liquid Handler Chosen by Colossal Biosciences to Accelerate NGS Capabilities in Fight Against Species Extinction and Biodiversity Loss

Cryo-EM Study Reveals Cas7-11-CRISPR Complex Regulation Mechanisms

New Chemical Modification Enhances Antisense Oligonucleotide Targeting in CNS Diseases

Multiplexed Orthogonal Base Editors for Precise Mutation Modeling

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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