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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study Offers Key Insights into the Structure of Neutral Mutations

An unexpected link between pure mathematics and genetics has been disclosed by an interdisciplinary group of mathematicians, physicists, engineers, and medical scientists. This helps disclose deep knowledge of the structure of neutral mutations and also the evolution of organisms.

2 Aug 2023

New Nanopore Technology Can Identify Single-Molecule Protein Variations

A group of researchers guided by the University of Oxford has made significant progress in detecting changes in protein structures. The method, which was published in Nature Nanotechnology, uses novel nanopore technology to detect structural variations at the single-molecule level, even deep within long protein chains.

2 Aug 2023

Single-Cell Sequencing Finds New Cell Types in the Visual Systems of Flies

Researchers from New York University have created a method that discovers and labels neurons throughout development, which has allowed them to identify novel cell types in the visual system of flies.

1 Aug 2023

RNA-Based CATCH Strategy Aims to Activate Dendritic Cells

Investigators at the Icahn School of Medicine at Mount Sinai have designed an innovative RNA-based strategy to activate dendritic cells-;which play a key role in immune response-;that eradicated tumors and prevented their recurrence in mouse models of melanoma.

28 Jul 2023

New Proof-of-Concept Model for Delivering Gene Editing Tools to Treat Blood Disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

28 Jul 2023

LION™-Formulated repRNA in Next-Gen repRNA Vaccine Platform Appears Promising

The creation of new vaccination technologies continues to be at the forefront of scientific inquiry as the globe fights numerous infectious illnesses. Recent research on illnesses like COVID-19 has shown promise for mRNA-based vaccines and their use of lipid nanoparticles (LNPs) for delivery.

25 Jul 2023

Atomic-Level Analysis of Synthetic DNA to Reveal New Treatment Options

West Virginia University researchers can now see synthetic DNA at the atomic level, allowing them to learn how to tweak its structure to improve its scissor-like function.

25 Jul 2023

Dietary Fiber Regulates Gut Microbiota and Improves Epithelial Cell Proliferation

A high-fiber diet is known to have several health benefits. Scientific studies point to protection against such diseases as cancer and diabetes.

25 Jul 2023

Essential Bacterial Signaling Autoproteolysis in C. thermocellum

Sensing and communicating with the extracellular environment are both aspects of transmembrane signaling.

24 Jul 2023

New Method for Building Modular Optical Sensors to Detect Bacteria and Viruses

An innovative method for building modular optical sensors that can detect viruses and bacteria has been created by an interdisciplinary research team from Bochum, Duisburg, and Zurich.

24 Jul 2023

The First Data Set Decoding RNA-Driven Phase Separations

High levels of semi-extractable RNAs are present in membraneless organelles in cells, and these RNAs could one day serve as biomarkers or therapeutic targets.

19 Jul 2023

Uncovering New Insights into Virus Self-Assembly

Griffith University researchers were instrumental in controlling the way viruses are assembled by using DNA “origami” templates.

18 Jul 2023

Berkeley Lab and Genentech Team Up to Develop Next-Generation Drug Delivery System

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

18 Jul 2023

New Study Identifies Aerobic Glycolysis Vital for Eye Development

According to a recent Northwestern Medicine study published in Nature Communications, aerobic glycolysis, the process by which cells convert glucose into lactate, is essential for eye development in mammals.

17 Jul 2023

New Insights into the Regulatory Network of Th17 Cells

N6-methyladenosine (m6A) is the most extensively studied RNA modification across multiple species, and its importance in the immune system has been demonstrated in a variety of contexts, including mRNA metabolism, cell differentiation, proliferation, and response to stimulation.

17 Jul 2023