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In the late 1980s and mid-1990s, genomes of diverse lineages of bacteria and archaea (the latter representing a domain of single-celled prokaryotic microorganisms) revealed clusters of regularly interspaced short palindromic repeats, known today under the abbreviation CRISPR. Later it was found that these repeat sequences (previously considered disparate) share a common set of features.

Genome editing tool used to render male mosquitoes infertile and slow disease spread

Mosquitos spread viruses that cause potentially deadly diseases such as Zika, dengue fever and yellow fever. New U.S. Army-funded research uses gene editing to render certain male mosquitoes infertile and slow the spread of these diseases.

24 Aug 2021

New CRISPR-based technique for rapid screening of hundreds of genes in a single experiment

Zebrafish- small, fast-growing creatures who share many of the same genes as humans- are instrumental to many biologists, who find them uniquely well suited for studying a wide range of questions, from how organisms develop to how the nervous system drives behavior.

From The University of Utah 20 Aug 2021

Researchers modify CRISPR to enable antibody-based medical diagnostics

Researchers adapted CRISPR to analyze antibodies in patient blood samples to pave the way for a new class of medical diagnostics.

From Harvard Medical School 16 Aug 2021

New technique can map out nearly all of the regulatory switches across a maize genome

Getting a full understanding of how genes are regulated is a major goal of scientists worldwide. Now, a Florida State University professor and his research partners have developed a technique that can map out nearly all of the likely regulatory switches across a genome.

16 Aug 2021

Scientists take step to engineer crops with higher yields by improving photosynthesis

In order to feed a projected 9 billion people by 2050, farmers need to grow 50% more food on a limited amount of arable land. As a result, plant scientists are in a race against time to engineer crops with higher yields by improving photosynthesis.

16 Aug 2021

Researchers use prime editing to correct mutations causing cystic fibrosis in organoids

A team of scientists rectified mutations that result in cystic fibrosis in cultured human stem cells.

11 Aug 2021

Muscle protein tied to physical fitness in youth and age-associated diseases

Researchers from Johns Hopkins Medicine say they have added to evidence that a protein called CaMKII improves strength, endurance, muscle health and fitness in young animals.

9 Aug 2021

Researchers identify key enzyme for producing a major industrial chemical in plants

Scientists studying the biochemistry of plant cell walls have identified an enzyme that could turn woody poplar trees into a source for producing a major industrial chemical.

6 Aug 2021

Researchers seek to develop a genome editing pipeline in carrots

Yiping Qi continues his research to increase the reach and utility of CRISPR gene-editing technologies, thanks to two new funding sources.

3 Aug 2021

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Study shows how to unlock CRISPR’s potential to regulate many genes simultaneously

A new technique to regulate several genes in engineered yeast cells could pave the way for the highly efficient, sustainable production of bio-based products.

19 Jul 2021

Study investigates people’s response to the use of genome editing in agriculture

Researchers have analyzed how people from five different countries respond to different usages of genome editing in the field of agriculture.

13 Jul 2021

Study reveals causal gene in autism model mice with copy number variation

A new study has unraveled a causal gene (Necdin, NDN) in autism model mice that exhibit the chromosomal abnormality known as copy number variation.

13 Jul 2021

Carrying out CRISPR/Cas9 in Space

In our latest interview, AZoLifeSciences spoke to a team of researchers about their latest research which involved carrying out CRISPR/Cas9 in Space.

8 Jul 2021

CRISPR-Cas9 system could help perform very effective target gene silencing

CRISPR-Cas9's extraordinary ability to modify specific areas of DNA has made it a favorite among gene-editing tools for researchers.

6 Jul 2021

New 3Cs multiplex approach enables the study of the effect of genetic changes

Dr Manual Kaulich’s team at Goethe University has developed a new 3Cs multiplex approach that permits the effect of genetic alterations in any two genes to be investigated simultaneously in cell cultures.

25 Jun 2021

Groundbreaking field trials underscore the potential of gene-editing technology

Field trials that explore healthy chemicals in agronomically significant brassica crops have underscored the “immense potential” of gene-editing technology.

22 Jun 2021

'Enabler cells' in tumors could promote cancer metastasis

Just a small number of cells found in tumors can enable and recruit other types of cells nearby, allowing the cancer to spread to other parts of the body, report Georgetown Lombardi Comprehensive Cancer Center scientists.

17 Jun 2021

Scientists design new gene drive to stop the transmission of devastating diseases

CRISPR-based technologies offer enormous potential to benefit human health and safety, from disease eradication to fortified food supplies. As one example, CRISPR-based gene drives, which are engineered to spread specific traits through targeted populations, are being developed to stop the transmission of devastating diseases such as malaria and dengue fever.

From UC San Diego 3 Jun 2021

Scientists develop new method that enables single-cell RNA sequencing in large number of cells

RNA sequencing is a powerful technology for studying cells and diseases. In particular, single-cell RNA sequencing helps uncover the heterogeneity and diversity of our body.

2 Jun 2021