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Multidisciplinary analysis of WGS improves diagnostic rates

The NHS Genomic Medicine Service, launched by the Department of Health in the United Kingdom in 2018, enables patients with unusual conditions to have their complete genetic code evaluated in the hopes of gaining a critical diagnosis.

From University College London 8 Nov 2022

Georgia Tech researchers develop a new biomaterial that could cure Type 1 diabetes

Insulin injections to treat Type 1 diabetes could become a thing of the past, but finding the cure faces many challenges.

4 Nov 2022

DNA-based nanotransporters could improve treatment of cancers, other diseases

A team of Canadian researchers from Université de Montréal has designed and validated a new class of drug transporters made of DNA that are 20,000 times smaller than a human hair and that could improve how cancers and other diseases are treated.

2 Nov 2022

Molecular mechanisms behind mitochondrial dysfunction in chronic heart failure

Chronic heart failure induces dysfunction in the cell’s powerhouses, which is caused in part by an excess of an essential intermediate compound in energy production. Compensating for this by supplementing the diet could be a potential technique for treating heart failure.

26 Oct 2022

Genome Editing Has A New Code

In this interview, we speak to Samantha Maragh, the leader of the genome editing program at NIST, about the genome editing vocabulary and what this means for researchers worldwide.

From National Institute of Standards and Technology (NIST) 21 Oct 2022

Nonconducting W434F mutant varies in structure and conformation

Potassium (K+) channels are tiny, highly specialized conduits found in every live cell that transfer K+ ions in an exceedingly selective and quick manner across cell membranes.

13 Oct 2022

Distinct roles of aging and genetics on expression phenotypes

Research conducted by the University of California, Berkeley, found that individual distinctions in human DNA matter less as people age and become more susceptible to aging disorders like diabetes and cancer.

10 Oct 2022

Broadening the scope of CRISPR-Cas9 genome editing systems

A group of Northwestern University researchers has created a novel gene editing platform that might influence the future application of a nearly infinite library of CRISPR-based therapeutics.

7 Oct 2022

Dogs can discriminate between baseline and stress odors

The physiological processes associated with an acute psychological stress response produce changes in human breath and sweat that dogs can detect with an accuracy of 93.75%, according to a new study published this week in the open-access journal PLOS ONE by Clara Wilson of Queen's University Belfast, UK, and colleagues.

29 Sep 2022

Special blood vessels may protect whales from brain damage while swimming

Special blood vessels in whale brains may protect them from pulses, caused by swimming, in their blood that would damage the brain, new UBC research has suggested.

23 Sep 2022

Native 3D structure of the ciliary base witnessed for the first time

Because flaws in the cilia transport system can result in, for example, blindness or cystic kidneys, findings reported in Science offer new understandings of the molecular basis for different diseases.

20 Sep 2022

Spaceflight increases the risk of developing cancer and heart disease

A groundbreaking study from the Icahn School of Medicine at Mount Sinai found that astronauts are more likely to experience mutations that could be connected to spaceflight and increase their lifetime risk of acquiring cancer and heart disease.

2 Sep 2022

Scientists discover latent stem cells that respond to injury in the central nervous system of mice

Scientists at the Francis Crick Institute have identified a group of latent stem cells that respond to injury in the central nervous system of mice. If a similar type of cell exists in humans, they could offer a new therapeutic approach to treat brain and spinal cord injuries.

23 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

COVID-19 spike protein caused severe heart damage, new research shows

Heart damage is prevalent in COVID-19 patients, leading many to doubt how the virus impacts the heart.

28 Jul 2022

Research shows how protein deficiency creates motor disorders in flies

Scientists at the Universities of Bonn and Osnabrück have identified a protein that when defective in flies results in motor dysfunction.

26 Jul 2022

Applying AI technology to boost Florida’s ailing citrus industry

As news broke that Florida's citrus industry ended this year's growing season with its lowest production in eight decades, an unlikely union has formed between two University of Florida startup companies to help reverse the trend.

25 Jul 2022

Experts develop new single-cell “chromatin atlas” of the human genome

Researchers from the University of Virginia School of Medicine have developed a crucial new tool that provides a better understanding of how genes in particular cells affect the risk of developing heart disease, the world’s leading cause of death.

25 Jul 2022

Scientists discover the first structures of angiotensin-converting enzyme using cryo-EM

University of Cape Town (UCT) researchers have used cryo-electron microscopy to identify the first complete structures of the human angiotensin-converting enzyme (ACE) (cryo-EM). A protein that controls blood pressure, ACE, is essential for maintaining good heart health.

14 Jul 2022

Researchers discover the atomic structure of the nuclear pore complex

Nearly 100 trillion cells make up the human body, which is what keeps people healthy and alive. The mechanisms of life are maintained by the billions of pieces that each cell has on its own.

14 Jul 2022