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Mount Sinai researchers illuminate the role of DNA methylation in Alzheimer's disease

Mount Sinai researchers have published a study in Alzheimer's & Dementia: The Journal of the Alzheimer's Association that sheds new light on the role of DNA methylation in Alzheimer's disease (AD).

23 Feb 2023

Study shows how convalescent plasma can be used as effective treatment during future pandemics

Three years into the COVID-19 pandemic, new variant outbreaks continue to fuel economic disruptions and hospitalizations across the globe.

22 Feb 2023

Adults struggling with chronic constipation benefit from a vibrating capsule

A vibrating capsule designed to stir the colon to action appears to double the ability for adults struggling with debilitating chronic constipation to defecate more normally and without drugs, researchers report.

22 Feb 2023

Novel model system helps studying human ovarian biology

Despite the fact that we all start out as an egg cell in one of our mother's ovaries, these human reproductive organs are surprisingly under-studied. Scientists have been working on creating in vitro models of human ovaries so that we can learn more about them and develop treatments for ovarian conditions, but most existing models use a combination of human and mouse cells, which do not faithfully replicate human ovary functions and take a long time to grow in the lab.

22 Feb 2023

Human sleep architecture varies substantially across seasons, study shows

Whether we're night owls or morning larks, our body clocks are set by the sun. Theoretically, changing day length and light exposure over the course of the year could affect the duration and quality of our sleep.

20 Feb 2023

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Iron-dependent cell death (ferroptosis) is a type of programmed cell death by means of which the body kills off diseased, defective or superfluous cells.

20 Feb 2023

Revealing a novel form of ferroptosis that may be implicated in diseases caused by acute injury

This study is led by Dr. Anjian Xu (Beijing Clinical Research Institute, Beijing Friendship Hospital, Capital Medical University), Dr. Min Cong (Liver Research Center, Beijing Friendship Hospital, Capital Medical University) and Dr. Junying Ding (Beijing Key Laboratory of Basic Research with Traditional Chinese Medicine on Infectious Diseases, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University).

20 Feb 2023

CD5-expressing dendritic cells help to prime T cell responses against cancer

Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced in 2011.

17 Feb 2023

New approach to rapidly determine biological aging

Telomeres-;the caps at the ends of chromosomes that protect our genetic materials from the brunt of cellular wear and tear-;are known to shorten and fray over time.

16 Feb 2023

Scientists correct limb length in mouse model of autosomal dominant Robinow Syndrome

Robinow Syndrome is the best known of a set of genetic disorders that affect the growth and development of the skeletal system.

16 Feb 2023

The essential protein needed for immune evasion and tumor cell metabolism

Typically, tumor cells change their energy metabolism and take in more glucose to enable their rapid division and spread. As a result, the body’s immune response to cancer is suppressed by limiting the immune cells’ access to glucose.

15 Feb 2023

IGSF3-mediated potassium dysregulation drives glioma-related epilepsy

Glioma is one of the most aggressive malignant primary brain tumors. A common feature of glioma is the presence of localized, intermittent seizures referred to as glioma-related epilepsy, which is known to promote tumor growth. However, the mechanism involved at the molecular level is still not clear.

15 Feb 2023

3D structure of a major protein complex in cilia revealed

Researchers at St. Jude Children’s Research Hospital have solved the 3D structure of an important protein complex in cilia, which are signaling appendages found on cells. The structure was pictured at the highest resolution available at the time.

15 Feb 2023

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

Individuals with cocaine use disorder exhibit gene expression changes in two brain regions: the nucleus accumbens, a region associated with reward, and the caudate nucleus, a region mediating habit formation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published February 10 in Science Advances.

13 Feb 2023

Specific types of gut fungi play a role in infant weight gain and growth

Researchers in the Cumming School of Medicine (CSM) at the University of Calgary in collaboration with the Canadian CHILD Study have found a link between the diversity, or number, of fungal species in the infant gut and the body-mass index (BMI) of infants.

10 Feb 2023

Hospital News and Research

Mount Sinai researchers illuminate the role of DNA methylation in Alzheimer's disease

Study shows how convalescent plasma can be used as effective treatment during future pandemics

Adults struggling with chronic constipation benefit from a vibrating capsule

Novel model system helps studying human ovarian biology

Human sleep architecture varies substantially across seasons, study shows

Iron-dependent cell death can be used to improve immunotherapies against liver cancer

Revealing a novel form of ferroptosis that may be implicated in diseases caused by acute injury

CD5-expressing dendritic cells help to prime T cell responses against cancer

New approach to rapidly determine biological aging

Scientists correct limb length in mouse model of autosomal dominant Robinow Syndrome

The essential protein needed for immune evasion and tumor cell metabolism

IGSF3-mediated potassium dysregulation drives glioma-related epilepsy

3D structure of a major protein complex in cilia revealed

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

Specific types of gut fungi play a role in infant weight gain and growth

Novel compound curtails influenza virus replication

Protein-rich droplets in cells linked to many unresolved diseases

Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Complete Genomics Drops Genome Sequencing Price to Sub $100 at AGBT General Meeting

New database of genotype-phenotype associations for monogenic cardiovascular diseases

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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