Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Personalized Mini-Brains Provide Insight into Autism Spectrum Disorder

Using stem cells generated from patients with a rare and severe form of autism spectrum disorder and intellectual disability, Scripps Research scientists have grown personalized "mini-brains" (or organoids) to study the disorder in new detail.

24 Oct 2024

Discovery of RNA Brake Offers Insights into Neurodevelopmental Disorders

When a gene produces too much protein, it can have devastating consequences on brain development and function.

24 Oct 2024

Study Uncovers Mechanism Behind B-Cell Maturation in Leukemia

Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic Leukaemia (B-ALL) next year in Spain, according to the latest projections from the Spanish network of cancer registries (REDECAN).

23 Oct 2024

New Insights into SARS-CoV-2’s Evasion of Innate Immunity

The novel coronavirus SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses.

23 Oct 2024

New Bacterial Toxins Discovered as Potential Weapons Against Infections

Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections.

23 Oct 2024

Structural Insights into Bacteriophages Open Doors for New Therapeutics

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

23 Oct 2024

New Study Uncovers How Viral Infections Trigger Pain, Identifies Potential Target for Relief

Findings indicate nociceptors detect viral nucleic acids, activating STING and TRPV1, highlighting new pain mechanisms in viral infections like HSV-1.

23 Oct 2024

Phages Form Unique 3D Shapes, Boosting Disease Detection

While preparing slides to be examined under a powerful microscope, a team of McMaster researchers who frequently work with bacteriophage viruses that consume bacteria had a pleasant and potentially very significant surprise.

22 Oct 2024

Unlocking the Secrets of Life Through Synthetic Biology

It is one of the most fundamental questions in science: how can lifeless molecules come together to form a living cell? Bert Poolman, Professor of Biochemistry at the University of Groningen, has been working on this problem for over twenty years.

22 Oct 2024

How Cancer Cells Use Ribosomes to Evade the Immune System

The protein factories of our cells are much more diverse than we thought they were. Scientists from the Netherlands Cancer Institute have now shown that cancer cells can use these so-called ribosomes to boost their invisibility cloak, helping them hide from the immune system.

22 Oct 2024

Advancements in Understanding Intestinal Hormone Secretion

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion.

21 Oct 2024

Researchers Discover GAME15's Role in Steroidal Compound Biosynthesis

Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum.

21 Oct 2024

Study Uncovers How MANF Protein Enhances Cellular Homeostasis and Longevity

McMaster University researchers have discovered a previously unknown cell-protecting function of a protein, which could open new avenues for treating age-related diseases and lead to healthier aging overall.

21 Oct 2024

Discovering the Molecular Mechanisms Behind Chicken Feather Patterns

Birds possess unique skin appendages called feathers that are derived from the outermost layer of skin cells. Feathers are important for several functions, such as flight, temperature regulation, protection from external stimuli, and mating behavior.

21 Oct 2024

Recombinant Expression and Glycosylation of EBN Mucin

The first recombinant mucin protein obtained from the Edible-nest Swiftlet Aerodramus fuciphagus (AfMuc) has been successfully identified and synthesized by a research team.

21 Oct 2024

A Novel Regulator of RNA Processing in Alzheimer's Disease

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that modifies the process of protein synthesis and impacts RNA processing in Alzheimer's patients' brains.

21 Oct 2024

DeepUrfold: A New AI Model Uncovers Hidden Protein Relationships and Redefines Fold Space

This study introduces DeepUrfold, a deep learning model that uncovers subtle structural links between proteins, advancing the field of protein evolution.

21 Oct 2024

Researchers Unravel Plant-to-Fungi Communication Using Baker's Yeast

Researchers at the University of Toronto have cracked the code of plant-to-fungi communication in a new study published in the journal Molecular Cell.

18 Oct 2024

Human Organoids Provide Insights Into Gut Hormone Release

A collaborative team of researchers from the Hubrecht Institute and Roche’s Institute of Human Biology has formulated strategies to identify the regulators involved in intestinal hormone secretion.

18 Oct 2024

MANF Protein Found to Boost Cellular Clean-Up and Efficiency

Researchers at McMaster University have uncovered a previously unrecognized function of a protein that helps protect cells, potentially leading to new treatments for age-related conditions and promoting healthier aging.

18 Oct 2024