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Rethinking Antibiotics: Dental Professionals Embrace New Alternatives For Standard Dental Procedures

Bacterial resistance to antibiotics poses a threat to global health, and the WHO highlights the consequences of inappropriate and excessive antibiotic use.

22 Nov 2023

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology.

22 Nov 2023

Gene Splicing Affects CD20 Expression and Response to Cancer Immunotherapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

17 Nov 2023

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA-;loops of DNA found outside of regular chromosomes-;are twice as likely to relapse and three times as likely to die within five years of diagnosis.

15 Nov 2023

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

15 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

LJI Scientists Uncover New Superpower of MAIT Cells

Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented type of T cell.

13 Nov 2023

Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -; 451 in all -; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

10 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

Researchers Develop Novel Antifungal Drug with Potential to Save Lives

Scientists at the University of Illinois Urbana-Champaign, in collaboration with researchers at the University of Wisconsin-Madison, have developed a novel antifungal molecule.

9 Nov 2023

GOV UK Introduces New 'AI Life Sciences' Fund - IEEE Comments

Last week, the UK Government announced it will be launching the AI Life Sciences Accelerator Mission. Approximately £100 million will be allocated to help drive AI innovation and tackle the UK’s biggest healthcare challenges

9 Nov 2023

Rising Prevalence of Chronic Rhinosinusitis in Japan: Causes and Implications

Chronic rhinosinusitis (CRS) is an inflammatory condition affecting the nasal cavity and sinuses, which can be categorized into eosinophilic and non-eosinophilic subtypes.

7 Nov 2023

Epigenetic Changes Drive Cancer Development

Every cell makes its own proteins by accessing the genetic information on its genes. Changes in this information, called mutations, may ruin the function of the affected proteins.

7 Nov 2023

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful.

7 Nov 2023

Understanding the Dynamic Regulation of Manchette Microtubules in Sperm Development

A team of researchers, led by Wenxiang Meng from the Institute of Genetics and Developmental Biology at the Chinese Academy of Sciences, has demonstrated that the deletion of the calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) gene in mice, which is associated with the minus ends of non-centrosomal microtubules, results in a condition known as oligoasthenoteratozoospermia.

6 Nov 2023

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Scientists have unraveled the mechanism by which a particular metabolite regulates DNA repair activity and the susceptibility of tissues to cancer treatment.

3 Nov 2023

Research Reveals How Gut Bacteria Influence Distant Organs Through Oxytocin Signaling

The gut microbiome, a community of trillions of microbes living in the human intestines, has an increasing reputation for affecting not only gut health but also the health of organs distant from the gut.

3 Nov 2023

Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication.

2 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

Clinical News and Research

Rethinking Antibiotics: Dental Professionals Embrace New Alternatives For Standard Dental Procedures

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Gene Splicing Affects CD20 Expression and Response to Cancer Immunotherapy

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

Cancer Stem Cells Induce Macrophage Senescence, Creating Conditions for Tumor Formation

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

LJI Scientists Uncover New Superpower of MAIT Cells

Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

Researchers Develop Novel Antifungal Drug with Potential to Save Lives

GOV UK Introduces New 'AI Life Sciences' Fund - IEEE Comments

Rising Prevalence of Chronic Rhinosinusitis in Japan: Causes and Implications

Epigenetic Changes Drive Cancer Development

Researchers Enhance CAR-T Cell Therapy by Preventing T-Cell Exhaustion

Understanding the Dynamic Regulation of Manchette Microtubules in Sperm Development

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Research Reveals How Gut Bacteria Influence Distant Organs Through Oxytocin Signaling

Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Novel Activation Mechanism for First Identified Oncogene

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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