Immune System News and Research

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Analyzing the antimicrobial resistance profile of the main agent of urinary tract infections

The human intestine is an environment inhabited by many bacteria and other microorganisms collectively known as the gut microbiome, gut microbiota or intestinal flora. In most people, it contributes to wellness. A healthy gut indicates a stronger immune system, improved metabolism, and a healthy brain and heart, among other functions.

14 Mar 2023

Developing new therapies that leverage the host immune system

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis. A relative, Yersinia pseudotuberculosis, causes gastrointestinal illness and is less deadly but naturally infects both mice and humans, making it a useful model for studying its interactions with the immune system.

14 Mar 2023

Understanding the relationship between gut microbiome and CAR T-cell therapy response

Microorganisms live in or on almost every part of the human body and play an important role in the regulation of normal human processes. As a result, changes in the number or type of microorganisms, also known as the microbiome, can contribute to disease and altered responses to therapy, including cancer treatment.

14 Mar 2023

Rest boosts the immune system of migratory birds, study finds

Exercising too much and not getting enough rest is bad for your health. A new study from Lund University in Sweden shows that the same is true for migratory birds. They need to rest not only to renew their energy levels but also in order to boost their immune system.

13 Mar 2023

Investigating the potential cellular effects of C-reactive protein

The biological function of the C-reactive protein, CRP, has long been unidentified. Investigators at LiU have discovered that this protein has a useful function in the inflammatory disease systemic lupus erythematosus or SLE.

10 Mar 2023

Pathogenic fungus binds to a human protein to escape elimination from lung cells

The pathogenic fungus Aspergillus fumigatus escapes elimination from surface cells of the human lung by binding to a human protein.

9 Mar 2023

Deeper understanding of T-cell responses may lead to better, more personalized immunotherapies

For the first time, a research team has identified and analyzed the steps by which immune cells "see" and respond to cancer cells, providing insights into reasons some treatments may be effective for certain patients but not others.

9 Mar 2023

Pentamer shape of C-reactive protein can suppress the immune response in inflammatory disease

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory disease.

9 Mar 2023

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

Combining discoveries in cancer immunology with sophisticated genetic engineering, Columbia University researchers have created a sort of "bacterial suicide squad" that targets tumors, attracting the host's own immune cells to the cancer to destroy it. The new work, published today in Science Advances, marks a major step forward in efforts to enlist non-pathogenic bacteria to combat cancer.

9 Mar 2023

Study findings reveal drug development possibilities for brain diseases

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

9 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

8 Mar 2023

Researchers track a specialized garbage disposal cell inside lymph nodes for the first time

For almost 140 years, the origin and behavior of an enigmatic cell type inside lymph nodes, called a tingible body macrophage, has remained a mystery.

3 Mar 2023

Applying crocodile’s unique pH sensing mechanism to benefit humans

Researchers from La Trobe University have just discovered how crocodiles, despite living in dirty water, prevent deadly fungal infections by employing a unique pH sensing mechanism.

3 Mar 2023

Regulatory T cells produced in the gut play a role in repairing injured muscles

The human immune system is incredibly versatile. Among its most skilled multitaskers are T cells, known for their role in everything from fighting infection to reining in inflammation to killing nascent tumors.

3 Mar 2023

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

CN Bio, a leading Organ-on-a-Chip (OOC) company that designs and manufactures single-and multi-organ microphysiological systems (MPS), today announced the commercial launch of the PhysioMimix™ Single-organ Higher Throughput (HT) System.

From CN Bio Innovations Limited 28 Feb 2023

Study uncovers differences in how AstraZeneca and Pfizer COVID-19 vaccines affect the immune system

A new Australian study led by SAHMRI and Flinders University has uncovered fundamental differences in how the AstraZeneca and Pfizer COVID-19 vaccines impact the immune system.

23 Feb 2023

UTA professor leads a state-funded project to explore how T-cells detect cancer

A University of Texas at Arlington bioengineering professor is leading a state-funded project that will try to identify what T-cells are detecting in cancerous cells to better craft a personalized cancer immunotherapy.

23 Feb 2023

LMU physician explores the causes of high susceptibility to deadly infections in prematurely born babies

LMU physician Markus Sperandio has discovered why the immune system of prematurely born babies is not working properly after birth.

23 Feb 2023

Mount Sinai researchers reveal mechanisms underlying autoimmunity in Down syndrome

Scientists at the Icahn School of Medicine at Mount Sinai in New York have identified which parts of the immune system go awry and contribute to autoimmune diseases in individuals with Down syndrome.

23 Feb 2023

Immune System News and Research

Analyzing the antimicrobial resistance profile of the main agent of urinary tract infections

Developing new therapies that leverage the host immune system

Understanding the relationship between gut microbiome and CAR T-cell therapy response

Rest boosts the immune system of migratory birds, study finds

Investigating the potential cellular effects of C-reactive protein

Pathogenic fungus binds to a human protein to escape elimination from lung cells

Deeper understanding of T-cell responses may lead to better, more personalized immunotherapies

Pentamer shape of C-reactive protein can suppress the immune response in inflammatory disease

“Bacterial suicide squad” recruits and activates innate and adaptive antitumor immune responses

Study findings reveal drug development possibilities for brain diseases

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Researchers track a specialized garbage disposal cell inside lymph nodes for the first time

Applying crocodile’s unique pH sensing mechanism to benefit humans

Regulatory T cells produced in the gut play a role in repairing injured muscles

CN Bio extends microphysiological system portfolio with PhysioMimix Single-Organ Higher Throughput System

Study uncovers differences in how AstraZeneca and Pfizer COVID-19 vaccines affect the immune system

UTA professor leads a state-funded project to explore how T-cells detect cancer

LMU physician explores the causes of high susceptibility to deadly infections in prematurely born babies

Mount Sinai researchers reveal mechanisms underlying autoimmunity in Down syndrome

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