Immune System News and Research

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Novel inhibitor, hopeaphenol, blocks HIV expression

In the United States, around 1.2 million people are living with HIV as of 2022. Many of these people can now live productive, symptom-free lives thanks to antiretroviral therapies, but a solution that permanently removes HIV from an infected person’s body is still a long way off.

30 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

Researchers develop a novel probe for selectively dyeing M1 and M2 macrophages

M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis.

28 Mar 2023

Resistance genes in human gut influenced by national trends in antibiotic consumption

According to a new study performed at the Earlham Institute and Quadram Institute in Norwich, the community of microbes living in and on human bodies might be serving as a reservoir for antibiotic resistance.

28 Mar 2023

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

One of the ways that cancer cells hide from the body's immune system is by forming a thin surface barrier called the glycocalyx.

27 Mar 2023

New insights into how different countries' research establishments respond to disease outbreaks

In a new study, researchers examined how a country's number of published 3D protein structures for coronaviruses, including the one responsible for COVID-19, correlated with its economic output and population.

27 Mar 2023

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

The removal of obsolete and damaged cell components by the body is crucial for fighting diseases like tuberculosis (TB), which establish themselves inside human cells, according to researchers from the Francis Crick Institute.

27 Mar 2023

Generating functional patient-specific thymic organoids from human pluripotent stem cells

Researchers have used pluripotent stem cells to make thymus organoids that support the development of patient-specific T-cells, researchers report March 23rd in the journal Stem Cell Reports.

24 Mar 2023

Common Epstein-Barr virus may be a trigger for multiple sclerosis

In 1868, French physician Jean-Martin Charcot, known as the founder of modern neurology, defined a disease entity in which multiple plaques formed in the brain and spinal cord, with varying physical symptoms, called Sclérose en plaques, or in English as multiple sclerosis (MS).

24 Mar 2023

Immunity adaptation found in genomes of Stone Age farmers

New research suggests that diversity in genes implicated in immunity might have facilitated the shift from hunter-gatherer lifestyles to agriculture that occurred in prehistoric Europe over the course of around 1,500 years.

23 Mar 2023

Blunted inflammatory response in obese individuals responsible for susceptibility to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

23 Mar 2023

Identifying the underlying causes of rare genetic immune disorders

The activated PI3K Delta syndrome 2 (APDS2) is a rare genetic disease that is caused by cellular anomalies, according to experts from the Garvan Institute of Medical Research.

23 Mar 2023

Novel tool analyzes how immune cells respond to SARS-CoV-2 vaccination

A study discovered that the magnitude and quality of a key immune cell’s response to two doses of the Pfizer-BioNTech COVID-19 vaccine were significantly lower in individuals with earlier SARS-CoV-2 infection compared to individuals without previous infection.

21 Mar 2023

New study pinpoints key source of T cell "exhaustion"

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies.

21 Mar 2023

T cell-driven changes in the gut may affect brain function associated with depression

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.

21 Mar 2023

Blunted inflammatory response could make obese patients more susceptible to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

21 Mar 2023

Macrophages likely to be a potential target for ER+ breast cancer

Most immunotherapies that aim to increase T cell activity are ineffective in treating estrogen receptor-positive (ER+) breast cancer. A new study of invasive ER+ breast cancers led by researchers at the University of Pittsburgh School of Medicine implies that targeting a different type of immune cell called macrophages may be a more effective approach.

From University of Pittsburgh 20 Mar 2023

Immune System News and Research

Novel inhibitor, hopeaphenol, blocks HIV expression

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Researchers develop a novel probe for selectively dyeing M1 and M2 macrophages

Resistance genes in human gut influenced by national trends in antibiotic consumption

Thickness of cancer cells' glycocalyx barrier determines immune cell evasion of tumors

New insights into how different countries' research establishments respond to disease outbreaks

Immune system’s aptitude in reducing reliance on antibiotics for treating infections

Generating functional patient-specific thymic organoids from human pluripotent stem cells

Common Epstein-Barr virus may be a trigger for multiple sclerosis

Immunity adaptation found in genomes of Stone Age farmers

Blunted inflammatory response in obese individuals responsible for susceptibility to severe COVID-19

Identifying the underlying causes of rare genetic immune disorders

Novel tool analyzes how immune cells respond to SARS-CoV-2 vaccination

New study pinpoints key source of T cell "exhaustion"

T cell-driven changes in the gut may affect brain function associated with depression

Blunted inflammatory response could make obese patients more susceptible to severe COVID-19

Macrophages likely to be a potential target for ER+ breast cancer

Study discovers the ability of certain blood immune cells to proliferate

New antibody "cocktail" may help counter the Lassa virus

Immune landscape in invasive ER+ breast cancers reveals a macrophage-driven microenvironment

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