Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Approximately 5% of people with Covid-19 progress to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.

20 Jul 2020

Yale researchers uncover mechanism driving Wolfram Syndrome

Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment.

20 Jul 2020

Study shows how cells respond to nutrient deprivation

The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell's organelles as power plants, factories, roads, libraries, warehouses and more.

From Harvard Medical School 17 Jul 2020

Study unravels the mysteries of variation in microbiome composition

Oregon State University researchers have made a key advance in understanding how timing impacts the way microorganisms colonize plants, a step that could provide farmers an important tool to boost agricultural production.

17 Jul 2020

Viral load peaks in early stages of COVID-19, study shows

In a retrospective study, investigators from New York University Langone Health found that the quantity of SARS-CoV-2 (viral load) collected from patients in the emergency department is significantly higher in patients with fewer or milder symptoms who did not require hospitalization--the opposite of what might be expected.

15 Jul 2020

Changes in glioblastoma cells influence the effect of different drugs, shows study

Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways.

15 Jul 2020

Healthy microbiome can reduce severity of chickungunya disease

Chikungunya virus, once confined to the Eastern Hemisphere, has infected millions of people in the Americas since 2013, when mosquitoes carrying the virus were discovered in the Caribbean.

15 Jul 2020

UVA scientists identify oncogene responsible for glioblastoma

Scientists have identified an oncogene (a cancer-causing gene) responsible for glioblastoma, the deadliest brain tumor.

15 Jul 2020

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

Nearly 20% of all COVID-19-associated deaths are from cardiac complications, yet the mechanisms from which these complications arise have remained a topic of debate in the cardiology community.

15 Jul 2020

PET radiotracer is safe and effective for imaging malignant brain tumors

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

14 Jul 2020

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research (WRAIR) have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

14 Jul 2020

Severely injured donor lungs can be recovered using cross-circulation platform

Respiratory disease is the third leading cause of death worldwide, and lung transplantation is still the only cure for patients with end-stage lung disease.

14 Jul 2020

Compound in pickled capers can activate proteins required for bodily processes

A compound commonly found in pickled capers has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.

14 Jul 2020

Study shows sex hormones alter the behavior of non-sex organs

In one of the first studies addressing the role of sex hormones' impact on stem cells in the gut, scientists outline new insights showing how a steroidal sex hormone, that is structurally and functionally similar to human steroid hormones, drastically alters the way intestinal stem cells behave, ultimately affecting the overarching structure and function of this critical organ.

10 Jul 2020

Metabolomics can help understand the impact of calorie-restricted diets on aging

Changes in a few small molecules involved in a cell's metabolism seem to indicate whether a restricted "life extension" diet will actually extend, shorten, or have no effect on lifespan, a study of fruit flies has found.

10 Jul 2020

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

10 Jul 2020

Black raspberries may reduce skin inflammation associated with allergies, mouse study shows

Eating black raspberries might reduce inflammation associated with skin allergies, a new study indicates.

6 Jul 2020

Researchers identify protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

6 Jul 2020

Rapid genomic profiling of colon cancers can improve therapy

Genomic mutation testing is critical to the therapeutic selection and management of patients with colorectal cancer.

29 Jun 2020

Blocking A 'Jamming Signal' Can Unleash Immune System To Fight Tumors

Yale researchers have discovered a "jamming signal" that blocks a powerful immune system stimulant called interleukin-18 (IL-18) from reaching tumors.

25 Jun 2020

Pathology News and Research

Type 1 interferon deficiency in the blood could be a hallmark of severe COVID-19

Yale researchers uncover mechanism driving Wolfram Syndrome

Study shows how cells respond to nutrient deprivation

Study unravels the mysteries of variation in microbiome composition

Viral load peaks in early stages of COVID-19, study shows

Changes in glioblastoma cells influence the effect of different drugs, shows study

Healthy microbiome can reduce severity of chickungunya disease

UVA scientists identify oncogene responsible for glioblastoma

High amount of SARS-Cov-2 receptor is present in patients with pre-existing cardiac conditions

PET radiotracer is safe and effective for imaging malignant brain tumors

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Severely injured donor lungs can be recovered using cross-circulation platform

Compound in pickled capers can activate proteins required for bodily processes

Study shows sex hormones alter the behavior of non-sex organs

Metabolomics can help understand the impact of calorie-restricted diets on aging

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Black raspberries may reduce skin inflammation associated with allergies, mouse study shows

Researchers identify protective antibodies for rare, polio-like disease in children

Rapid genomic profiling of colon cancers can improve therapy

Blocking A 'Jamming Signal' Can Unleash Immune System To Fight Tumors

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