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Research focuses on understanding production of memory B cells and immune responses

The current COVID-19 climate has made vaccines, antibodies, and immune responses topics of everyday conversation. Now, it isn't just immunologists who want to know how our bodies respond to re-infections months, years, or sometimes decades after an initial immune response.

From Osaka University 13 Oct 2020

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

13 Oct 2020

Stem cells that promote bone repair can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

13 Oct 2020

Dopamine and serotonin found to be involved in perception, cognitive capacities

In first-of-their-kind observations in the human brain, an international team of researchers has revealed two well-known neurochemicals -- dopamine and serotonin -- are at work at sub-second speeds to shape how people perceive the world and take action based on their perception.

13 Oct 2020

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

It's one of the world's deadliest animals, and it has a taste for human blood: the mosquito. Mosquitoes spread diseases like malaria, dengue, and yellow fever that kill at least a half a million people each year. Now researchers are learning what humans taste like to mosquitoes, down to the individual neurons that sense blood's distinctive, delectable flavor.

13 Oct 2020

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

In a healthy brain, the multistep waste clearance process known as autophagy routinely removes and degrades damaged cell components - including malformed proteins like tau and toxic mitochondria.

13 Oct 2020

Components leaking from broken muscle fibers activate 'satellite' muscle stem cells

While building a muscle damage model in a cultured system, a research collaboration between Kumamoto University and Nagasaki University in Japan has found that components leaking from broken muscle fibers activate "satellite" muscle stem cells.

13 Oct 2020

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

SARS-CoV-2 continues to cause an ongoing pandemic as of October 2020, with over 35 million reported cases and over 1 million deaths around the world.

13 Oct 2020

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Every eukaryotic organism contains the so-called transposons, which are abundant DNA-elements.

13 Oct 2020

Severe cases of COVID-19 resemble systemic lupus erythematosus

Scientists from Emory Health Sciences have been observing an intense stimulation of immune cells in severe cases of COVID-19 disease. This activation of immune cells is similar to acute flares of systemic lupus erythematosus (SLE)—an autoimmune disease.

13 Oct 2020

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Volume 11, Issue 28 of Oncotarget features "Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation" by Gaba et, al. which reported that reliable development of Oncopig HCC cell lines was demonstrated through hepatocyte isolation and Cre recombinase exposure across 15 Oncopigs.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Researchers test the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Virologists at the KU Leuven Rega Institute have been working on two lines of SARS-CoV-2 research: searching for a vaccine to prevent infection, and testing existing drugs to see which one can reduce the amount of virus in infected people.

12 Oct 2020

Genomes provide insights into fig-wasp coevolution

Banyan trees are fig trees that begin their life as an epiphyte. The most noticeable feature of banyan Ficus species is their extraordinary aerial roots, which enable them to live as hemi-epiphytes, as do the strangler figs often seen in tropical forests.

12 Oct 2020

Scientists shed light on immune evasion strategy used by malaria-causing parasite

The Plasmodium parasite, which transmits malaria to humans through infected mosquitos, triggers changes in human genes that alter the body's adaptive immune response to malarial infections, according to a team of researchers at NYU Abu Dhabi.

12 Oct 2020

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

12 Oct 2020

Biofilms of major pathogenic bacteria can deform soft surfaces

The vast majority of bacteria in the world live on surfaces by forming structures called "biofilms". These communities host thousands to millions of bacteria of different types, and are so biologically complex and active that scientists describe them as "cities".

9 Oct 2020

Study offers new insights how the plant tips stay free of virus

Plants are able to keep growing indefinitely because they have tissues made of meristems--plant stem cells--which have the unique ability to transform themselves into the various specialized cells that make up the plant, dividing whenever appropriate and producing new cells of whatever type as needed.

9 Oct 2020

Reducing the harvest period of stem cell sheets to two days

Stem cells are cell factories that constantly divide themselves to create new cells. Implanting stem cells in damaged organs can regenerate new tissues.

9 Oct 2020

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

A new radioimmunotherapy has proven effective in reversing resistance to the most commonly used lymphoma drug, rituximab, according to research published in the October issue of The Journal of Nuclear Medicine.

9 Oct 2020

Cell News and Research

Research focuses on understanding production of memory B cells and immune responses

Study clarifies role of ERβ in growth and regeneration of skeletal muscle in female mice

Stem cells that promote bone repair can also generate arthritic bone spurs

Dopamine and serotonin found to be involved in perception, cognitive capacities

Researchers trace neurons in mosquitoes that sense blood's distinctive flavor

Enzyme SSH1 impairs disposal of damaged tau and mitochondria leaking toxins

Components leaking from broken muscle fibers activate 'satellite' muscle stem cells

Scientists identify molecular mechanisms of IFN responses in COVID-19 disease

Researchers identify mechanism that silences “parasitic” DNA-elements in pluripotent stem cells

Severe cases of COVID-19 resemble systemic lupus erythematosus

Oncopig fulfills the unmet clinical modeling needs for hepatocellular carcinoma

Scientists discern molecular mechanisms underlying plant parasitism and cross-species grafting

Researchers test the effect of hydroxychloroquine versus favipiravir in SARS-CoV-2−infected hamsters

Genomes provide insights into fig-wasp coevolution

Scientists shed light on immune evasion strategy used by malaria-causing parasite

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Biofilms of major pathogenic bacteria can deform soft surfaces

Study offers new insights how the plant tips stay free of virus

Reducing the harvest period of stem cell sheets to two days

New radioimmunotherapy effectively reverses resistance to lymphoma therapy

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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