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Analysis of genetic factors contributing to cleft lip and palate

Cleft lip and palate, which are mainly caused by genetic reasons, are two of the most common congenital malformations. It is still unknown which genes are exactly affected.

19 Dec 2022

RXR: A key protein in the balanced production of different blood cells

In the regulation of hematopoietic stem cells—which are the immature stem cells that produce all the blood cell lineages—the cell protein retinoid X receptor (RXR) is an important element.

19 Dec 2022

Scientist honored for his contribution on ALS research

The Drs Ayeez and Shelena Lalji & Family ALS Endowed Award for Innovative Healing was given to Clive Svendsen, PhD, a pioneer in regenerative medicine, for his significant contributions to the field of amyotrophic lateral sclerosis (AL) at Massachusetts General Hospital’s Sean M. Healey & AMG Center for ALS.

12 Dec 2022

Predictive classifier identifies patients who can skip radiation therapy

According to the findings of a meta-analysis proposed at the San Antonio Breast Cancer Symposium held on December 6–10th, 2022, patients with invasive breast cancer who had low scores on an investigational gene molecular signature seemed to have similar rates of local recurrence regardless of whether they received adjuvant radiation therapy after breast-conserving surgery.

12 Dec 2022

Stress hormones produced by salmon could be leading to increased infections

Fish farming is a crucial industry in Norway, and salmon is by far the most important species. So it's alarming that bacterial diseases are on the rise at the massive sea farms where salmon are raised.

7 Dec 2022

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

The link between tandem repeats and development of Schizophrenia

Each human cell is distinct because it is written in the DNA language.

1 Dec 2022

Specific genetic variant resulting in the early onset of epilepsy identified

Children’s Hospital of Philadelphia (CHOP) researchers have identified a particular genetic variant in SCN1A, the most common genetic epilepsy, that contributes to an earlier start of epilepsy with clinical features different from other epilepsies.

1 Dec 2022

Microglial cells trigger inflammatory protective mechanisms in the immune system

Microglia, the brain’s own immune cells, are present in the central nervous system.

1 Dec 2022

Acute infection disrupts the healthy balance between the good and bad gut microbes

Rutgers researchers examined the impact of COVID-19 on patients’ microbiomes, the group of microbes that live in and on the human body.

From Rutgers University 30 Nov 2022

Importance of localizing BRCA gene mutations for ovarian cancer treatment

Mutations in the BRCA1 and BRCA2 genes, which are inherited by 1 in 400 and 1 in 800 persons, respectively, elevate the risk of various malignancies such as ovarian, breast, pancreatic, and prostate cancer considerably.

30 Nov 2022

Discovery provides insights into how invertebrates have evolved complex nervous systems

Octopuses are not much like humans -; they are invertebrates with eight arms, and more closely related to clams and snails.

29 Nov 2022

Study unravels a novel function of the gene scissors

Many years earlier, the CRISPR/Cas9 gene scissors have been making a sensation in science and medicine. This new tool of molecular biology consists of its origins in an ancient bacterial immune system.

28 Nov 2022

Atypical antibody shows extremely potent zika-resistant activity

A group of researchers led by Weill Cornell Medicine, New York-Presbyterian, and National Institutes of Health (NIH) investigators has discovered an unusual type of antibody that, even at extremely low concentrations, neutralizes the Zika virus and renders the virus infection undetectable in preclinical models.

22 Nov 2022

3D “mini eyes” provide insight into genetically induced blindness

The development of “mini eyes” by researchers at the UCL Great Ormond Street Institute of Child Health (UCL GOS ICH) has made it possible to study and comprehend the onset of blindness in the rare genetic disease known as Usher syndrome more.

From University College London 22 Nov 2022

A gene’s function in embryonic development

An international study led by the medical school at the University of Bonn has discovered a gene that is crucial to the growth of the human embryo. Abnormalities of different organ systems may occur if it is changed.

16 Nov 2022

Regeneration of the immune system in MS patients

Transplanting blood stem cells is a new but incredibly successful treatment for multiple sclerosis. Now, a study directed by the University of Zurich has looked closely at how the autoimmune disease is controlled by the treatment and how the immune system recovers afterward.

14 Nov 2022