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gnomAD Consortium releases first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

29 May 2020

Biophysicists shed light on how optogenetic tool works

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

29 May 2020

Study identifies potent neutralizing antibodies against SARS-CoV-2

A joint research team led by Sunney Xie, Director of Beijing Advanced Innovation Center for Genomics at Peking University has successfully identified multiple highly potent neutralizing antibodies against the novel coronavirus SARS-CoV-2, the causative virus of the respiratory disease COVID-19, from convalescent plasma by high-throughput single-cell sequencing.

29 May 2020

Study provides new strategies for treating different types of cancer

An RNA molecule involved in preventing the formation of tumors can modify its structure and thus regulate the production of proteins in the cell.

29 May 2020

New methodology could help differentiate between healthy and cancer cells

Scientists have pioneered the use of whole living cells (that is, human lung adenocarcinoma) in dynamic combinatorial chemistry systems.

29 May 2020

Warwick researchers discover how cells respond to fasting and activate autophagy

As modern life-styles and high-calorie diets drive the UK's obesity levels up, researchers from the University of Warwick have found how cells respond to fasting and activate the process called autophagy, which means a healthier lifestyle can be promoted to help people maintain a healthy body weight.

From The University of Warwick 28 May 2020

New CRISPR-Cas9 based method for directed protein evolution

"Directed evolution" is the process by which scientists produce tailor-made proteins for cell biology, physiology and biomedicine in the laboratory.

28 May 2020

Study highlights crucial role of immune-system molecule in Huntington's disease

More than a decade before people with Huntington's disease show symptoms, they can exhibit abnormally high levels of an immune-system molecule called interleukin-6 (IL-6), which has led many researchers to suspect IL-6 of promoting the eventual neurological devastation associated with the genetic condition.

28 May 2020

New study outlines the mechanisms behind cell fusion

Scientists have known for a decade that cells that fuse with others to perform their essential functions - such as muscle cells that join together to make fibers - form long projections that invade the territory of their fusion partners.

28 May 2020

Scientists explain why cold-adapted enzymes stop functioning at room temperature

Enzymes from cold-loving organisms that live at low temperatures, close to the freezing point of water, display highly distinctive properties.

28 May 2020

AXT offer Fluicell’s innovative range of tissue engineering systems in Australia & NZ

AXT are proud to announce that they have just expanded their life science product portfolio with the addition of Fluicell’s innovative tissue engineering systems. The new agreement will see AXT exclusively distribute their Biopixlar and BioPen product lines in Australia and New Zealand.

From AXT Pty Ltd 28 May 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

Study shows how ocean virus captures the metabolism of carbon-storing bacteria

Below the surface of the ocean, a virus is stealing the metabolism of the most abundant organism present on Earth. That might be attractive to those who breathe above the ocean’s surface.

28 May 2020

Damped circadian oscillations observed in the absence of KaiA protein in cyanobacterium

Circadian rhythms are driven by a highly autonomous, self-sustaining circadian clock in our cells, telling us when to sleep or wake up in a 24-hour cycle.

27 May 2020

Study discovers how protein inhibits tumor development in mice

Proteins are found throughout our cells and regulate a lot of biological processes that are important for our survival.

27 May 2020

Nanodevices give unprecedented peek into how cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

From University of Bath 27 May 2020

New minimally invasive method allows cells to be sampled over time

At any given moment, a variety of dynamic processes occur inside a cell, with many developing over time. Because current research methods for gene profiling or protein analysis destroy the cell, study is confined to just that one moment in time, and researchers are unable to return to the cell to examine how things change beyond that snapshot.

27 May 2020

The eye launches an immune response in the lens following injury

The lens of the eye is an unusual organ. Unlike most of the body's organs, blood vessels don't reach the lens. If they did, they'd obscure our vision and we wouldn't be able to see. The lack of vasculature led scientists to believe immune cells, which travel via the bloodstream, couldn't get to this part of the body either.

27 May 2020

Mechanically rejuvenated fibroblasts show promise in stem cell engineering

Fibroblasts synthesize the collagen, creating the structural framework for animal tissues, and play a significant role in the process of wound healing.

27 May 2020