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New microbiome study could enable new treatments for middle ear infections

The main cause of preventable hearing loss and deafness in Indigenous communities is chronic middle ear infections.

10 Nov 2021

Whole genome sequencing for children with cancer provides accurate diagnosis

According to a new study, revealing the entire genetic code for each child diagnosed with cancer could unravel new treatment options.

10 Nov 2021

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia.

3 Nov 2021

New eToeholds could make RNA therapeutics more safer and effective

RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.

29 Oct 2021

Scientists identify gene crucial to sperm cell production

Scientists at Cincinnati Children's appear to have flipped another piece in the underexplored puzzle of male infertility.

27 Oct 2021

Low dose of pollutants in food leads to high activation of antibodies that cause allergic response

Exposure to the heavy metal cadmium is known to irritate the stomach and lungs or cause kidney disease, but new research links another health issue to inadvertently ingesting low doses of the pollutant: high activation of the antibodies that cause an allergic response.

27 Oct 2021

Cell-free DNA employed to identify measurable residual disease

Researchers demonstrated that cell-free DNA from CSF could be employed to examine MRD in children treated for the brain tumor medulloblastoma.

25 Oct 2021

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

As scientists have probed the mysteries of life down to smaller and smaller scales, they have invented tools to help them understand what they observe.

22 Oct 2021

Targeted drug shows promise against brain metastases from kidney cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

22 Oct 2021

AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

An artificial intelligence (AI)-based technology rapidly diagnoses rare disorders in critically ill children with high accuracy, according to a report by scientists from University of Utah Health and Fabric Genomics, collaborators on a study led by Rady Children's Hospital in San Diego. The benchmark finding, published in Genomic Medicine, foreshadows the next phase of medicine, where technology helps clinicians quickly determine the root cause of disease so they can give patients the right treatment sooner.

From The University of Utah 18 Oct 2021

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear to be long-lasting, with 90% of patients who received the treatment eight to 11 years ago still disease-free.

18 Oct 2021

Scientists show how skin T cells can damage other organs in stem cell transplant patients

More than 40,000 allogeneic hematopoietic stem cell transplants are carried out worldwide every year, mostly for patients suffering from leukemia or other diseases of the hematopoietic system.

15 Oct 2021

Parents' stress during COVID-19 affected eating habits of children

The incredible stress parents experienced during the COVID-19 pandemic had a negative effect on the eating habits of their children, according to a new study by researchers at the University of Houston College of Education.

13 Oct 2021

Study: Sex matters when it comes to susceptibility to infections and other health conditions

A University of Alberta-led study shows that when it comes to susceptibility to infections and other health conditions, sex matters.

13 Oct 2021

Study finds higher levels of air pollutants in regions near oil and gas wells

In a 14-year analysis of air quality across California, Stanford researchers observed higher levels of air pollutants within 2.5 miles of oil and gas wells, likely worsening negative health outcomes for nearby residents.

13 Oct 2021

Regulatory network impacting brain evolution found in “junk DNA,” says study

Human DNA has a close resemblance to that of the chimpanzee, which in evolutionary terms is the closest living relative of humans.

13 Oct 2021

Wild meat consumption reduces greenhouse gas emissions, study reveals

Consuming sustainably sourced wild meat instead of domesticated livestock reduces greenhouse gas emissions and retains precious tropical forest systems, which in turn mitigates the effects of climate change.

8 Oct 2021

Researchers identify the mechanism leading to deafness in Norrie disease

A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.

6 Oct 2021

Supercomputer-driven dynamic model reveals hidden process in X chromosome inactivation

Using supercomputer-driven dynamic modeling based on experimental data, researchers can now probe the process that turns off one X chromosome in female mammal embryos.

5 Oct 2021

Study sheds light on blood and immune systems development in prenatal bone marrow

Researchers carried out the first extensive investigation of the formation of the blood and immune systems in the prenatal bone marrow.

4 Oct 2021

Children News and Research

New microbiome study could enable new treatments for middle ear infections

Whole genome sequencing for children with cancer provides accurate diagnosis

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

New eToeholds could make RNA therapeutics more safer and effective

Scientists identify gene crucial to sperm cell production

Low dose of pollutants in food leads to high activation of antibodies that cause allergic response

Cell-free DNA employed to identify measurable residual disease

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

Targeted drug shows promise against brain metastases from kidney cancer

AI-powered tool rapidly identifies genetic causes of rare disorders with high accuracy

Pioneering gene therapy has long-lasting effects on children with deadly immune disorder

Scientists show how skin T cells can damage other organs in stem cell transplant patients

Parents' stress during COVID-19 affected eating habits of children

Study: Sex matters when it comes to susceptibility to infections and other health conditions

Study finds higher levels of air pollutants in regions near oil and gas wells

Regulatory network impacting brain evolution found in “junk DNA,” says study

Wild meat consumption reduces greenhouse gas emissions, study reveals

Researchers identify the mechanism leading to deafness in Norrie disease

Supercomputer-driven dynamic model reveals hidden process in X chromosome inactivation

Study sheds light on blood and immune systems development in prenatal bone marrow

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