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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Unearthing Beal’s Time Capsule: The 144-Year-Old Seed Experiment

In April of 2021, a clandestine gathering took place on the Michigan State University campus, where four plant scientists from the university unearthed a bottle filled with seeds that had been buried over 144 years ago by the renowned MSU botanist, William J. Beal.

8 Nov 2023

Genomic Sequencing Reveals Songbird’s Secrets

Researchers have deciphered the genetic foundation responsible for the striking diversity in body size that is evident among song sparrows, a cherished and widely recognized species of North American songbirds.

8 Nov 2023

Unlocking the Secrets of Bacterial Transcription

Bacterial transcription serves as an assembly line for duplicating genetic directives from double-stranded DNA into RNA molecules.

7 Nov 2023

Unveiling the Role of Foxp3 in Shaping Chromatin Architecture of Regulatory T Cells

Regulatory T cells, or Tregs, represent a specialized class of immune cells dedicated to quelling immune responses and safeguarding the body against self-attack.

7 Nov 2023

Epigenetic Changes Drive Cancer Development

Every cell makes its own proteins by accessing the genetic information on its genes. Changes in this information, called mutations, may ruin the function of the affected proteins.

7 Nov 2023

Plants Exploit Randomness to Avoid Mitochondrial Damage

Humans wouldn't last long without plant mitochondria and chloroplasts. These essential compartments of plant cells famously capture sunlight and power plant life – and so, ultimately, provide all the food we eat.

7 Nov 2023

Dendritic Cells Reprogram Their Genes to Enhance Immune Response

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), under the leadership of Professor Francisco Sánchez-Madrid, have discovered that dendritic cells, responsible for triggering targeted immune responses, possess the ability to modify their genes in order to enhance their immune reactivity.

6 Nov 2023

CRISPR-Cas9 Enzyme's Magnesium Role Unraveled in DNA Cutting

The gene-editing technology known as CRISPR has led to revolutionary changes in agriculture, health research and more.

6 Nov 2023

Nucleotide Metabolite Controls DNA Repair and Cancer Sensitivity

Scientists have unraveled the mechanism by which a particular metabolite regulates DNA repair activity and the susceptibility of tissues to cancer treatment.

3 Nov 2023

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

3 Nov 2023

Hidden Genetic Variations can be Detected Using New Nijmegen Method

Many hidden genetic variations can be detected with Chameleolyser, a new method developed in Nijmegen.

2 Nov 2023

Obesity Susceptibility may be Written Into Molecular Processes of Human Cells

A susceptibility to gain weight may be written into molecular processes of human cells, a Washington State University study indicates.

2 Nov 2023

DNA’s Role in Glioblastoma: Insights from Umeå University’s Research

A groundbreaking research conducted at Umeå University in Sweden has revealed that the three-dimensional arrangement of DNA can impact the development of aggressive brain cancer, glioblastoma.

1 Nov 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

Two Bee Species Become One as Researchers Solve Identity Puzzle

A new study by Curtin and Flinders Universities has found that what were thought to be two different species of native Australian bee are in fact one.

30 Oct 2023

The Role of CRISPR-Cas9 in Treating Primary Immunodeficiency Disorders

Severe Combined Immunodeficiencies (SCIDs) encompass a collection of serious primary immunodeficiency disorders primarily instigated by genetic mutations that disrupt the development of T-cells.

30 Oct 2023

Genetics can Improve the Diagnostic Value of Cyanobacterial Biomarkers

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

30 Oct 2023

Bacteriophages as Unexpected Allies in Mammalian Health

In a research study, Jeremy J. Barr, along with colleagues from Monash University in Victoria, Australia, present findings indicating that mammalian cells may uptake phages as a means to enhance cellular growth and survival.

27 Oct 2023

Novel Replacement Strategy Opens the Door to Therapeutic Interventions for Genomic Diseases

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development.

27 Oct 2023

Unraveling the Impact of Genetic Mutations on Future Generations

Regarding the structure of the human genome, it is only a matter of time until detrimental genes, which have the potential to jeopardize future generations, emerge within a population.

26 Oct 2023