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New ACMG Statement Urges Caution with Polygenic Risk Score Testing in Embryo Selection

Should we be using polygenic risk score assessment for embryo selection? Providing in-depth analysis, the Social, Ethical and Legal Issues Committee of the American College of Medical Genetics and Genomics (ACMG) has released a new Points to Consider statement to assist healthcare professionals and patients in understanding the safety and utility of preimplantation genetic testing for polygenic disorders (PGT-P) as a clinical service.

26 Feb 2024

Significant Increase in Antibiotic Resistance Genes Found in Humans and Livestock

Biomedical engineers at Duke University have discovered a significant connection between the dissemination of antibiotic resistance genes and the development of resistance to new drugs in specific pathogens

23 Feb 2024

Researchers Uncover Newly Identified Native Mouse Species

Australia can now claim two new species of native rodents, thanks to a study from The Australian National University (ANU).

23 Feb 2024

Mechanism of Cancer Drug Targeting Tumor Suppressor Genes Unveiled

Researchers have revealed the mechanism of a drug shown to be effective in treating certain types of cancer, which targets a protein modification silencing the expression of multiple tumor suppressor genes.

22 Feb 2024

Genetic Insights and Conservation Challenges of Nara's Sacred Deer

In a world where human activities have left an indelible mark on ecosystems, the preservation of species and natural landscapes has become an urgent global concern.

22 Feb 2024

The Promise of siRNA Nanomedicine for HIV Treatment

Society learned about the usefulness of mRNA during the COVID-19 pandemic when scientists and medical professionals leveraged its power to deliver a vaccine for the virus within a year.

21 Feb 2024

Genetic Clusters Linked to Type 2 Diabetes and Complications

The relationship between genetic variations and disease in order to create novel medications and therapies.

20 Feb 2024

Investigating the Link Between Metabolism and Intestinal Development

Intestines can reach a length of 15 feet or more; how does it fit within human bodies properly? The gut tube dramatically loops and rotates to bundle the extending intestine as the digestive system grows. Intestinal malrotation is a common, but poorly understood, birth defect caused by the failure of the gut to rotate correctly during development.

20 Feb 2024

Bulls Guide Research into Male Fertility Genetics

One in eight couples worldwide are unable to conceive within a year, or lifelong due to infertility, making it a common issue.

19 Feb 2024

The Surprising Link Between Tea Quality and Root Bacteria

The type of tea used to make a fine cup of tea will significantly impact its flavor. However, a study published in the journal Current Biology reveals that the collection of bacteria found on tea roots is another essential component needed to make a great cup of tea.

16 Feb 2024

The Role of Ancient Retroviruses in Vertebrate Brain Evolution

According to a study published in the journal Cell, ancient viruses may have contributed to the development of myelin and, consequently, the large, complex brains.

16 Feb 2024

Researchers Identify Genes Linked to Genomic Instability and DNA Damage

More than one hundred key genes linked to DNA damage have been uncovered through systematic screening of nearly 1,000 genetically modified mouse lines, in a new study published today (14 February) in Nature.

16 Feb 2024

New Understanding of DNA Damage and Disease Risk

Researchers identified 145 genes that are essential for the health of the genome and potential treatments for human genomic disorders.

15 Feb 2024

Unraveling Lenacapavir's Impact on the HIV Life Cycle

A new anti-retroviral medication for the treatment of human immunodeficiency virus (HIV) infections was licensed by the US Food and Drug Administration and the European Union just over a year ago.

14 Feb 2024

ReSisTrace: Unveiling Pre-Existing Treatment Resistance in Cancer Cells

In many cancers, such as ovarian cancer, each round of chemotherapy kills the majority of cancer cells, while a small population of them survives through treatment.

14 Feb 2024

Unleashing the Potential of CRISPR-COPIES

The last ten years have seen tremendous advancements in CRISPR/Cas systems. These precise genome editing tools can be used for more than just gene therapy and transgenic crop development.

13 Feb 2024

New CRISPR-Based Test Detects Mpox Faster

A rare viral illness called mpox, formerly known as monkeypox, is transmitted by direct physical contact between individuals.

12 Feb 2024

APOE4's Influence on Lipid Droplets in Brain Cells

The largest genetic risk factor for late-onset Alzheimer's disease is apolipoprotein E (APOE), and researchers Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen group, have made a novel discovery about this protein.

12 Feb 2024

Unlocking RNA Secrets: New Method Exposes Gene Expression's Hidden Hurdles

A new study demonstrates that a method may identify, for the first time, the frequency and precise location of a molecular occurrence known as "backtracking" across the genetic material (genome) of any species.

12 Feb 2024

Relation Between Faulty DNA Disposal System and Inflammation

The path from mitochondrial stress to leaking endosomes to immune system initiation in mouse cells is outlined by Salk scientists, providing new therapeutic targets to potentially reduce inflammation in aging and disease.

12 Feb 2024