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Researchers identify the molecular route that leads to autoimmune disease inflammation

Mitochondria are self-contained organelles that reside inside cells and are tasked with producing the chemical energy required to power vital tasks necessary for life and wellbeing. They have their own mini-chromosome and DNA.

From UC San Diego 14 Jul 2022

Rice University bioscientists use CRISPR to activate “silent” bacterium genes

In the quest for antibiotics to address the increasing issue of resistance in disease treatment, silence may be the best policy.

14 Jul 2022

Researchers investigate the effects of transient oxygen starvation on protein folding in plants

Protein molecules require a defined shape in order to function. When they are created, their building blocks are therefore linked together in a very specific way.

13 Jul 2022

Analyzing and acknowledging HIV protein may result in new treatments, study reveals

Researchers from Rutgers University and the Salk Institute defined the molecular structure of the HIV Pol polyprotein, a protein that helps the virus propagate and spread throughout the body, in an exploration that could lead to the formation of potential treatments for more than 40 million HIV patients globally.

From Rutgers University 11 Jul 2022

New method can identify the vast number of molecules derived from food

An international team of scientists, led by researchers at University of California San Diego, report a new method called untargeted metabolomics to identify the vast number of molecules derived from food that were previously unidentified, but that appear in our blood and our stool.

From UC San Diego 11 Jul 2022

Challenges in Drug Discovery; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we speak to Steve Rees, Vice-President of Discovery Biology at AstraZeneca, about the challenges currently faced by the drug discovery sector.

From Society for Laboratory Automation and Screening (SLAS) 8 Jul 2022

Study shows how drugs help to treat hepatitis A virus replication using an animal model

A virus must go through the viral replication cycle in order to propagate throughout the body and cause disease.

5 Jul 2022

Researchers target human protein to combat SARS-CoV-2 and other viruses

People are realizing now, more than two years into the COVID-19 disease outbreak, that the “new normal” will most likely involve practicing to coexist with SARS-CoV-2.

1 Jul 2022

New technique shows how tRNA folding changes help to treat RNA-linked diseases

Researchers have developed a novel technique to analyze the composition and quantity of “transfer RNAs, which are tiny, chemically modified RNAs involved in protein synthesis.

From Penn State University 1 Jul 2022

Researchers examine ancient microbes to find life beyond earth

Researchers have reproduced what life was like for some of the oldest species on Earth using light-capturing proteins found in living microorganisms. These initiatives may enable everyone to spot life in distant worlds, whose atmospheres mirror the pre-oxygen planet more closely.

1 Jul 2022

Researchers use nanopore-based DNA computing technology to detect cancer

The cancer type cholangiocarcinoma, often known as bile duct cancer, is characterized by a high fatality rate.

1 Jul 2022

Research sheds light on innovative techniques to improve drugs for diseases

In a paper that was just published in Science, scientists from Sweden’s Karolinska Institutet and SciLifeLab explain how they were able to enhance a protein’s capacity to repair oxidative DNA damage while also giving the protein a new role.

27 Jun 2022

Researchers discover a way for detecting resistance-encoding genes in bacteria

Chalmers University of Technology researchers have devised a method for detecting certain bacterial genes that encode resistance using conventional microscopes, which are already used to diagnose TB in low-income countries.

27 Jun 2022

Researchers capture a new high-resolution view of the rabies virus

Around 59,000 individuals are shockingly killed by the rabies virus each year, and several of them are children. Some victims, particularly children, discover they have been exposed after it is too late.

20 Jun 2022

Researchers reveal how blood serum impacts the survival and metabolism of bacteria

In hospitals, the Staphylococcus aureus bacteria can be transported from the skin or nasal cavity into open wounds and, possibly, the bloodstream, posing a fatal hazard. Staph infections killed over 20,000 Americans in 2017, according to the Centers for Disease Control and Prevention.

20 Jun 2022

Novel nanoparticle therapeutic shows potential for treating human cancers

Researchers from Wake Forest University School of Medicine have discovered a possible new approach to treating solid tumors through the creation of a novel nanoparticle. Solid tumors are found in cancers such as breast, head and neck, and colon cancer.

15 Jun 2022

Researchers demonstrate a possible new way of generating insulin-producing cells

Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.

14 Jun 2022

A signaling molecule can make plants more resistant to flooding, research shows

Extreme weather phenomena are on the rise worldwide, including frequent droughts and fires. Floods are also a clear consequence of climate change.

13 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Researchers developed a weapon to combat drug-resistant malaria

As the efficiency of conventional antimalarial medications deteriorates, a novel approach to combating malaria that sees the disease turn against itself could provide a viable treatment for the hundreds of millions of people affected globally every year.

6 Jun 2022