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Unveiling Progesterone's Impact on Cancer Immunosuppression

Researchers turned to pregnancy to explore why some cancers successfully evade the immune system and grow unchecked.

9 Jul 2024

Exploring Gut Microbiome Modulation for Disease Prevention

Carriers of gut Blastocystis, a single-celled organism that has been classified as either a parasite or harmless organism but is frequently found in the digestive system, were associated with markers of good cardiovascular health and decreased body fat in an analysis of over 50,000 people from around the world.

9 Jul 2024

A New Tool to Unravel the Mysteries of Metabolic Genes

A novel discovery platform has been created by a multidisciplinary research team to investigate the role of genes involved in metabolism, which is the culmination of all chemical reactions necessary for life.

9 Jul 2024

Integrating Genomic Data for Enhanced Fruit Tree Breeding

Genotyping techniques can be used to select fruit trees with desired traits at the seedling stage, increasing the efficiency of fruit tree breeding.

8 Jul 2024

New Guidelines Address Ethical Concerns of Stem Cell Embryo Research in the UK

The UK’s first guidelines for research with stem cell-grown embryo models state that all studies involving these models should be overseen by a dedicated committee.

8 Jul 2024

Comprehensive Analysis Identifies Risk Factors for Multiple Cancers

Scientists have discovered over 5,000 genetic variations that give rise to specific cancers, along with a possible therapeutic target that could be used to treat or even stop these cancers from growing.

8 Jul 2024

Scientists develop first fully functional human immune system in mouse model

Researchers at The University of Texas Health Science Center in San Antonio have produced a mouse model that is humanized, complete with a human immune system and a gut microbiome that resembles that of a human being and is able to elicit particular antibody responses.

8 Jul 2024

Selfish No More: Genetic Elements Give Phages a Competitive Edge

Curious bits of DNA tucked inside genomes across all kingdoms of life historically have been disregarded since they don't seem to have a role to play in the competition for survival.

7 Jul 2024

Study Reveals Key Genetic Interaction for Enhanced Drought Tolerance in Plants

Drought significantly impacts agricultural productivity and plant survival. Traditional methods for improving drought resistance, such as selective breeding and genetic modification, have had limited success.

5 Jul 2024

New Genetic Circuit Forces Cancer Cells to Self-Destruct

Treating cancer can sometimes feel like a game of Whac-A-Mole. The disease can become resistant to treatment, and clinicians never know when, where and what resistance might emerge, leaving them one step behind.

5 Jul 2024

Bowel Cancer Cells Use Genetic On-Off Switch' to Evade the Immune System

Bowel cancer cells have the ability to regulate their growth using a genetic on-off switch to maximize their chances of survival, a phenomenon that's been observed for the first time by researchers at UCL and University Medical Center Utrecht.

4 Jul 2024

UCL Study Uncovers Astrocytes' Role in Brain Energy Boosting Mechanism

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

4 Jul 2024

Understanding How Motorized Processes Shape Chromosome Structures and Influence Cellular Functions

Researchers at Rice University are making strides in understanding how chromosome structures change throughout the cell's life cycle.

4 Jul 2024

Unveiling the Role of Exons in Protein Foldability and Evolution

A new study led by Rice University's Peter Wolynes offers new insights into the evolution of foldable proteins. The research was published in the Proceedings of the National Academy of Sciences.

4 Jul 2024

Using Mobile Data to Track the Spread and Evolution of Superbugs

Key insights into the global spread, evolution, and resistance patterns of a major bacterium causing pneumonia and meningitis have been revealed through the combination of genomic data and human travel patterns over 14 years in South Africa.

4 Jul 2024

Innovative Approach to Protein Synthesis Funded by $2 Million Grant

The National Institutes of Health's Maximizing Investigators' Research Award (MIRA) program for established investigators has awarded Rice University chemist Han Xiao with nearly $2 million.

4 Jul 2024

Researchers Decode Impact of Every Possible Alteration in Critical Cancer Gene

Scientists at the Francis Crick Institute have mapped all possible outcomes of changes to a tumor-suppressing gene called VHL, as the first step in a massive research project to unravel the consequences of tens of thousands of genetic variations in genes linked to cancer.

4 Jul 2024

Metabolic Priming of CAR T Cells for Treatment of Solid Tumors

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently.

3 Jul 2024

TRPC5 Gene Alterations: A Key Player in Obesity and Postpartum Depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

3 Jul 2024

Small Molecules Offer Precise Control Over Splicing in Gene Expression

The correct functioning of cells relies heavily on the ability to finely control gene expression, a complex process by which the information contained in DNA is copied into RNA to eventually give rise to all the proteins and most of the regulatory molecules in the cell.

3 Jul 2024