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Longitudinal study identifies many genetic markers linked to bone mineral accrual

A multidisciplinary team of researchers led by Children's Hospital of Philadelphia has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

7 Jan 2021

Researchers find genetic correlations between inflammatory bowel disease and stress, depression

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children's Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.

30 Oct 2020

Cell nucleus may enable the cells to evade crowded environments

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free.

20 Oct 2020

Climate change-driven wildfires cause devastating health impacts

Immediate actions are needed to limit the greenhouse gas emissions that are driving climate change that helps fuel wildfires, a Monash University study says.

14 Oct 2020

New index relies on pigs to demonstrate protein quality for humans

Nearly a decade ago, the UN's Food and Agriculture Organization (FAO) developed a new index to assess protein quality in foods. The goal, writ large, was to address food security for the world's most vulnerable populations, creating more accurate tools for food assistance programs seeking to provide balanced nutrition.

24 Sep 2020

ADHD study reveals genetic differences between African Americans and people of European ancestry

Researchers from Children's Hospital of Philadelphia (CHOP) have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder (ADHD) between African Americans and people of European ancestry, which may play an important part in how patients of different ethnic backgrounds respond to treatments for this condition. The findings were published online by the journal Scientific Reports.

23 Sep 2020

Novel computational approach helps find genetic causes of severe childhood brain disorders

A team of researchers at Children's Hospital of Philadelphia affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have combined clinical information with large-scale genomic data to successfully link characteristic presentations of childhood epilepsies with specific genetic variants.

27 Aug 2020

Excessive consumption of fructose may lead to non-alcoholic fatty liver disease

Excessive consumption of fructose -; a sweetener ubiquitous in the American diet -; can result in non-alcoholic fatty liver disease (NAFLD), which is comparably abundant in the United States.

25 Aug 2020

Researchers find associations of lifelong antimicrobial drug use with saliva microbiota diversity

The human microbiota plays an important role in health and well-being by assisting in digestion, producing nutrients, resisting invading pathogens and regulating metabolism and the immune system.

25 Aug 2020

Simple blood test is useful in screening youth for prediabetes and diabetes

A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Aug 2020

Many consumers are confused by whole grain labels on food packaging

Whole grain labels on cereal, bread, and crackers are confusing to consumers and could cause them to make fewer healthy choices, according to the results of a study that tested whether people are able pick out the healthier, whole grain option based on food package labels.

11 Aug 2020

How sweet-taste perception changes with age

Compared with adults, children are less sensitive to the sweet taste and need 40% more sucrose for them to detect the taste of sugar, a new study found.

4 Aug 2020

CBT helps food allergic children with severe phobia of anaphylaxis

Imagine a young girl with a peanut allergy, so stricken by fear of anaphylaxis that she no longer takes part in everyday activities many children take for granted.

29 Jul 2020

Josep Carreras Institute creates spin-off to develop CAR-T based therapies for leukemia

The Josep Carreras Leukaemia Research Institute, a public centre pertaining to the Generalitat de Catalunya's (Government of Catalonia) CERCA network, has created the OneChain Immunotherapeutics spin-off, the aim of which is to develop new immuno-oncological therapeutic tools with various preclinical candidates, based on CAR-T technology for different tumors, such as cortical T-cell acute lymphoblastic leukemia (coT-ALL), a rare subtype of leukemia that mainly affects children, and which has a poor prognosis.

21 Jul 2020

Single dose of flu drug can limit the spread of the illness within households

A single dose of the flu drug baloxavir marboxil can reduce the spread of the illness within households, new research concludes.

14 Jul 2020

New spatial mapping method pinpoints new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

9 Jul 2020

Genetics could pave the way for better diagnosis and treatment of diabetes in Indians

A new way of using genetics to diagnose diabetes could pave the way for better diagnosis and treatment in Indians, new research has concluded.

From University of Exeter 15 Jun 2020

Do Chemical Pollutants Increase the Risk of Celiac Disease?

Do chemical pollutants increase the risk of celiac disease? AZoLifeSciences spoke to Abigail Gaylord and Dr. Jeremiah Levine to find out.

From New York University (NYU) 3 Jun 2020

ADHD-associated genetic variants have reduced progressively in human lineage

According to a study published in the Scientific Reports journal, the frequency of genetic variants linked to attention-deficit/hyperactivity disorder (ADHD) has reduced progressively in the evolutionary human lineage from the Palaeolithic to the present day.

29 May 2020

Study shows the significance of genetics evaluation and testing for solid tumor cancers

A new study performed by Cleveland Clinic has underscored the significance of genetic testing and genetic evaluation for young adults, adolescents, and children suffering from solid tumor cancers.

6 May 2020