Bladder News and Research

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Researchers uncover a new cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin (AAT) deficiency present with high variation in the severity of liver disease.

21 Oct 2020

Researchers discover a gene responsible for urination

In a National Institutes of Health (NIH)-funded study involving both mice and patients who are part of an NIH Clinical Center trial, researchers discovered that a gene, called PIEZO2, may be responsible for the powerful urge to urinate that we normally feel several times a day.

20 Oct 2020

Scientists find sensor protein which enables normal functioning of bladder

A team co-led by scientists at Scripps Research has found that the main sensor protein enabling our sense of touch also underlies the feeling of having a full bladder and makes normal bladder function possible.

15 Oct 2020

UroCAD assay shows better sensitivity than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

12 Oct 2020

Extrachromosomal DNA with potential to cause cancer drives poor patient outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

From UC San Diego 18 Aug 2020

Scientists discover gut bacteria’s role in battling cancerous tumors

Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine (CSM) have discovered which gut bacteria help our immune system battle cancerous tumors and how they do it.

14 Aug 2020

Research identifies how the gut communicates with spinal cord and brain

You're faced with a big decision so your second brain provides what's normally referred to as 'gut instinct', but how did this sensation reach you before it was too late?

27 Jul 2020

Study shows how inflammatory changes in tumors cause drug resistance in blood vessels

Scientists at Hokkaido University and collaborators have identified how inflammatory changes in tumors caused by chemotherapy trigger blood vessel anomalies and thus drug-resistance, resulting in the poor prognosis of cancer patients.

2 Jul 2020

New sampling method can more accurately detect genetic alterations in tumors

A wholistic tumor sampling method that more accurately detects genetic alterations in tumors, which are critical in allowing treatment to be personalized to each and every patient, has been developed by researchers from the Crick, Roche and The Royal Marsden NHS Foundation Trust and published in Cell Reports.

12 May 2020

Modifications to gut microbiome could slow cancer growth in smokers

Changes to the gut microbiome interacted with the immune system to slow the growth of cancer in mice exposed to cigarette smoke, according to research that was selected for presentation at Digestive Disease Week 2020.

30 Apr 2020

Scientists Recreate DNA Damage Caused By Toxins From Smoking

Researchers from the University of York have recreated how toxins from smoking cause unique patterns of DNA damage.

29 Apr 2020