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Holographic histopathology increases imaging speed, resolution for diagnostics

Histology involves the investigation of biological tissues at the microscopic level. Histology is also known as microscopic anatomy and is commonly used to diagnose cancer and other diseases.

3 May 2021

Study reveals novel antibody binding implicated in liver and breast cancer

In the field of structural biology, certain molecules are so uncommon that they can only be captured with a special set of tools.

18 Feb 2021

Research may help better understand the biochemistry underlying catalysis in cells

Investigators from the Institute of Scientific and Industrial Research at Osaka University, together with the Hiroshima Institute of Technology, have announced the discovery of a new protein that allows an organism to conduct an initial and essential step in converting amino acid residues on a crosslinked polypeptide into an enzyme cofactor.

From Osaka University 11 Feb 2021

Researchers develop novel nanobodies against SARS coronavirus-2

An international research team led by the University of Bonn has identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are much smaller than the classic antibodies used to treat US President Donald Trump, for example.

13 Jan 2021

Researchers determine atomic structure of coronavirus protein linked to disease severity

A team of HIV researchers, cellular biologists, and biophysicists who banded together to support COVID-19 science determined the atomic structure of a coronavirus protein thought to help the pathogen evade and dampen response from human immune cells.

13 Jan 2021

Research shows magnesium contact ions stabilize complex folded structure of tRNA

In cells transfer RNA (tRNA) translates genetic information from the encoding messenger RNA (mRNA) for protein synthesis.

10 Dec 2020

Scientists elucidate the structure of ABC transporter protein

A high concentration of salt or sugar in the environment will dehydrate microorganisms and stop them from growing.

19 Nov 2020

Glass surface embedded with self-assembled gold nanoparticles can improve live-cell imaging

In the quest to image exceedingly small structures and phenomenon with higher precision, scientists have been pushing the limits of optical microscope resolution, but these advances often come with increased complication and cost.

9 Nov 2020

Combination of microscopy and machine learning helps detect fossil pollen grains

Plant biology researchers at the University of Illinois and computer scientists at the University of California Irvine have developed a new method of fossil pollen identification through the combination of super-resolution microscopy and machine learning.

27 Oct 2020

New software helps analyze individual cells in virtual reality

New virtual reality software now enables scientists to “walk” inside and examine individual cells.

14 Oct 2020

New method reveals structural data of membrane proteins in explicit detail

The human body contains a vast number of proteins that are collectively called the proteome.

8 Oct 2020

Study explains the organization of genetic information contained within mitochondria

Mitochondria creates energy for cells, and are called the “powerhouse". The genetic information is present within the mitochondria for making this energy.

30 Sep 2020

Researchers develop new tool to predict protein disorder

Nobel Prize winner Christian Boehmer Anfinsen had demonstrated clearly that a protein is capable of finding its way back to its “native” 3D structure.

11 Sep 2020

High-speed AFM enables real-time visualization of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

18 Aug 2020

Researchers use super-resolution microscopy to study close protein associations

With the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

10 Jul 2020

Combination of ExM and SIM helps observe 3D ultrastructure of synaptonemal complex

The development of egg and sperm cells in all mammals, including humans, is significantly contributed by the synaptonemal complex—a ladder-like cell structure.

6 Jul 2020

New research advances the field of optical microscopy

New Illinois ECE research is advancing the field of optical microscopy, giving the field a critical new tool to solve challenging problems across many fields of science and engineering including semiconductor wafer inspection, nanoparticle sensing, material characterization, biosensing, virus counting, and microfluidic monitoring.

9 Jun 2020

Researchers create 3D fluorescence and phase imaging of living cells based on digital holography

A research group led by Kobe University's Professor MATOBA Osamu (Organization for Advanced and Integrated Research) has successfully created 3D fluorescence and phase imaging of living cells based on digital holography.

2 Jun 2020

Innovative two-photon microscopy enables in vivo subcellular imaging of the retina

Retina is the only part of the central nervous system that can be visualized noninvasively with optical imaging approaches.

21 May 2020

X-ray experiments reveal antibody to block entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

20 May 2020