Exhaustion News and Research

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Study shows major differences in mild versus severe COVID-19 infection

These days, a crucial question on people’s minds is how long does SARS-CoV-2 immunity last after infection?

22 Jan 2021

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center.

8 Dec 2020

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

Fine-tuning stem cell metabolism prevents hair loss

A team of researchers have discovered a mechanism that prevents hair loss: hair follicle stem cells.

29 Sep 2020

Researchers identify mechanisms that impair the immune system in response to viral infections

Scientists have discovered mechanisms that cause functional deterioration of the immune system in reaction to viral infections, including COVID-19 or HIV.

26 Aug 2020

Skeletal muscles help to keep the immune system functional in chronic diseases

In the fight against cancer or chronic infections, the immune system must be active over long periods of time.

16 Jun 2020

Exploring the cradle of hematopoietic stem cells

Researchers from the group of Catherine Robin at the Hubrecht Institute characterized the molecular landscape of the aorta that supports the generation of the first Hematopoietic Stem Cells (HSCs) in the embryo.

5 Jun 2020

Cytokine Storms And T Cell Counts May Offer Clues On How To Treat COVID-19

Cytokine storms may affect the severity of COVID-19 cases by lowering T cell counts, according to a new study published in Frontiers in Immunology.

1 May 2020

High-Fat Diet Consequences Include Mental Fatigue, Researchers Say

Obesity has been shown to place physical stress on the body, but new research suggests that excess weight may also cause mental fatigue.

28 Apr 2020

Study designs artificial proteins that function as molecular logic gates

Researchers are currently using the same fundamental tools that enable the working of computers to manipulate life at the molecular level.

6 Apr 2020