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A New Statistical Method to Mitigate AI Bias in Genetic Research

Researchers at the University of Wisconsin–Madison are cautioning that the growing use of artificial intelligence techniques in genetics and medicine may result in incorrect inferences regarding the relationship between genes and physical traits, such as risk factors for diseases like diabetes.

5 Nov 2024

Researchers Develop Synthetic Genes for Self-Assembling Biomaterials

Researchers from the UCLA Samueli School of Engineering and the University of Rome Tor Vergata in Italy have developed synthetic genes that function like the genes in living cells.

5 Nov 2024

APOE4 and Microglia Together Drive Alzheimer's Protein Deposits

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for Alzheimer's disease-;the same cells cause harmful inflammation and clumps of misfolded proteins, according to a new study by scientists at Gladstone Institutes.

5 Nov 2024

A Genomic Blueprint for Sustainable Macadamia Production

The genomes of all four Macadamia species have been successfully sequenced and combined by a research team, which represents a major breakthrough in crop development efforts for this commercially valuable nut.

4 Nov 2024

New Lab-Grown Lip Cells Could Transform Research and Treatment for Disfiguring Lip Conditions

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair effectively. Basic research is essential to improving these treatments, but until now, models using lip cells -; which perform differently to other skin cells -; have not been available.

4 Nov 2024

Immortalized Lip Cells Open Doors for Testing New Therapies

4 Nov 2024

Understanding the Dynamics of Stem Cells

Age influences stem cell survival and immune diversity, according to new research on the long-term dynamics of transplanted stem cells in a patient’s body.

1 Nov 2024

A New Understanding of Viral Infection

Scientists studying animal viruses with the potential to infect humans have discovered a critical protein that could facilitate the spread of a family of organisms known as arteriviruses.

1 Nov 2024

Unraveling the Spatial Complexity of Gene Expression with Seq-Scope

A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024

Study Links Archaic Gene Variant to Health Risks in First Nations Oceanians

An ancient gene mutation among First Nations inhabitants of Oceania may make them more susceptible to infectious diseases like influenza, according to a new study by scientists at the University of Colorado Anschutz Medical Campus.

30 Oct 2024

F-Actin Accumulation Impairs Brain Function in Aging Fruit Flies

Humans aren't the only ones who grow forgetful as they age -; fruit flies do, too. But because fruit flies have a lifespan of only about two months, they can be a useful model for understanding the cognitive decline that comes with aging.

29 Oct 2024

New Insights Into the Role of p53 in Intestinal Inflammation

A group of scientists from Charité – Universitätsmedizin and the Berlin Institute for Medical Systems Biology of the Max Delbrück Center have provided fresh insight into the pathophysiology of ulcerative colitis an inflammatory bowel disease that affects an estimated five million people globally and is associated with a higher risk of colon cancer.

28 Oct 2024

Novel Mechanism for GRB2-SOS1-Mediated Liquid-Liquid Phase Separation

Researchers at Tokyo Metropolitan University have discovered new details about how the proteins GRB2 and SOS1 in cells transmit signals from membrane receptors to nuclei.

28 Oct 2024

Groundbreaking Study Reveals New Insights into Fruit Fly Reproduction

You have likely not spent much time thinking about the uterus of the fruit fly, Drosophila melanogaster.

28 Oct 2024

Wobble Genomics advances early detection of breast cancer with RNA sequencing

Wobble Genomics, a healthcare and biotechnology company at the forefront of long-read RNA sequencing, will present data today demonstrating that its technology can detect rare full-length RNA transcript variants not picked up by other methods.

26 Oct 2024

Predicting Disease-Causing Protein Interactions with PIONEER

Researchers at Cornell University and Cleveland Clinic developed an open-access computational platform and online database that helps identify targetable interactions between proteins for therapeutic purposes.

25 Oct 2024

Zebrahub Offers Unprecedented Insight into Embryonic Development

When early cartographers undertook perilous expeditions to map unknown corners of the world with sextants, compasses, and hand-drawn diagrams, it's unlikely they imagined that someday anyone with an internet connection would have access to a seamless view of the entire planet from the comfort of their own home.

25 Oct 2024