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Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024

EMBL Researchers Develop Novel Photoacoustic Probes to Monitor Brain Activity

To understand the brain better, we need new methods to observe its activity.

28 Aug 2024

Computational Modeling and Experimental Findings on Nucleosome Constraining in Mitosis

Individual cells divide through a process called mitosis, during which the cell's copied DNA is separated between two resulting daughter cells. Despite recent advances in cell biology, the mechanism by which DNA condenses during mitosis is still poorly understood. Researchers recently tracked small stretches of DNA wound around histone proteins, called nucleosomes, to better characterize nucleosome behavior during cell division.

27 Aug 2024

Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

Research identifies two states of age-associated thymic epithelial cells, linking thymic degeneration to aging and injury, impacting immune system function.

26 Aug 2024

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Research on intestinal immuno-organoids reveals their potential in modeling immune interactions and studying intestinal diseases linked to cancer therapies.

26 Aug 2024

Breakthrough Discovery in Mitochondrial Recycling Could Impact Health Treatments

Mitochondria, the so-called "powerhouse of the cell," depend on a newly discovered recycling mechanism identified by scientists at The Hospital for Sick Children (SickKids).

22 Aug 2024

UChicago Team Secures $7.4 Million Grant to Study Cellular Adaptation

Cells use a variety of processes to adapt to changes and stressors in their environment, like increased temperature.

21 Aug 2024

New Imaging Technique Offers Clearer View of Brain Function

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.

16 Aug 2024

Spontaneous Brain Activity Drives Early Neural Circuit Formation

In humans, the process of learning is driven by different groups of cells in the brain firing together. For instance, when the neurons associated with the process of recognizing a dog begin to fire in a coordinated manner in response to the cells that encode the features of a dog -; four legs, fur, a tail, etc. -; a young child will eventually be able to identify dogs going forward. But brain wiring begins before humans are born, before they have experiences or senses like sight to guide this cellular circuitry. How does that happen?

16 Aug 2024

Deep-Learning Model Identifies Parkinson's Disease-Specific Neuroanatomical Features

A deep-learning-based contrastive approach to examine magnetic resonance imaging (MRI) scans from Parkinson’s disease patients.

14 Aug 2024

Advancing Genome Visualization with CRISPR/Cas9 Technology in Live Cells

Understanding the spatiotemporal organization of the genome in the nucleus is crucial for advancing our knowledge of chromatin structure and its functional dynamics in both normal and diseased states.

13 Aug 2024

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

The ability to alter or prevent the expression of faulty genes in the brain could be leveraged as a powerful therapeutic against neurodegenerative disease. However, the molecular underpinnings of the living brain are still largely inaccessible, hampering progress on such promising therapeutics.

9 Aug 2024

Imaging News and Research

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

EMBL Researchers Develop Novel Photoacoustic Probes to Monitor Brain Activity

Computational Modeling and Experimental Findings on Nucleosome Constraining in Mitosis

Study Utilizes Flow Cytometry and Advanced Transcriptomics to Reveal Age-Related Defects in Thymic Regeneration

New Human Intestinal Immuno-Organoids Reveal Insights into Immune Cell Dynamics and Cancer Immunotherapy

Breakthrough Discovery in Mitochondrial Recycling Could Impact Health Treatments

UChicago Team Secures $7.4 Million Grant to Study Cellular Adaptation

New Imaging Technique Offers Clearer View of Brain Function

Spontaneous Brain Activity Drives Early Neural Circuit Formation

Deep-Learning Model Identifies Parkinson's Disease-Specific Neuroanatomical Features

Advancing Genome Visualization with CRISPR/Cas9 Technology in Live Cells

Noninvasive Ultrasound Method Enables Tracking of Gene Expression in Specific Brain Regions

UCL Scientists Uncover New Role of Ribosomes in Protein Folding

Novel Microscopy Method Revolutionizes Imaging with Reduced Radiation and Faster Results

New CRISPR-Based Test Achieves Rapid Detection of Tuberculosis

The Role of Chemical Proteomics in Understanding Small Molecule-Protein Interactions

Probing Plasma Membrane Dynamics with Cryo-Electron Microscopy

Novel ATP Imaging System Reveals Insights into Kidney Energy Metabolism

High Performance SEM Helps Drive NZ Towards a Smart, Green Future

Cell Dynamics Drive Dramatic Shape Changes in Insect Development

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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