Mitochondria News and Research

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Unveiling the Role of NCLX Protein in Mitochondrial Calcium Regulation and Autophagy

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by mitochondria, the organelles that generate energy for cells; and autophagy induced by calorie restriction.

3 May 2024

First Comprehensive Map of Protein Movement in Yeast Cell Cycle Revealed

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle.

23 Apr 2024

Researchers Identify Link Between Mitochondrial Depletion and Protein Build-Up in Neurons

Researchers from Tokyo Metropolitan University have identified how proteins collect abnormally in neurons, a feature of neurodegenerative diseases like Alzheimer's.

22 Apr 2024

Unveiling Cannabinoid’s Potential for Treating Age-Related Brain Degeneration

Scientists at the Salk Institute observed the neuroprotective effects of cannabinol in fruit flies and discovered cannabinoid analogs that may prove to be promising future treatments for Parkinson's, Alzheimer's, and traumatic brain injury.

18 Apr 2024

OrthoID Method Revolutionizes Protein Identification in Organelle Communication

A collaboration between POSTECH, Daegu Catholic University School of Medicine, and Seoul National University unveils a novel strategy for identifying key proteins in organelle communication.

15 Apr 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

RNA Modification Offers Hope for Treating Neurological Diseases

The research team led by Yongchao C. Ma, Ph.D., at the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, uncovered a fundamental biological mechanism that holds promise for the development of novel treatments for neurological disorders like spinal muscular atrophy (SMA) and autism, as well as various types of cancer.

5 Apr 2024

Insulin Influences Mitochondrial Recycling in Neurons

The hormone insulin controls many cellular processes and adapts them to the body's current energy supply.

20 Mar 2024

New Research Into the Impact of Microplastics and Nanoplastics on Human Health is Urgently Required Due to ‘Significant Threat’ to Human Health

A new metastudy published in Cambridge Prisms: Plastics by Cambridge University Press, has identified a body of evidence demonstrating the negative impact of microplastics and nanoplastics (MPs and NPs) on human health and identifying the limitations of current research.

20 Mar 2024

Targeting T Cell Metabolism to Boost Cancer Therapies

Recent findings from the lab of Jessica Thaxton, PhD, MsCR, in the UNC School of Medicine's Department of Cell Biology and Physiology, as well as associates in the Lineberger Comprehensive Cancer Center's Immunotherapy Group, have provided new insights into T-cell metabolism that may improve immunotherapies that depend on T cells to combat cancer.

18 Mar 2024

New Solvatochromic Dye Could Revolutionize Real-Time Lipid Order Imaging

A new solvatochromic probe could help shed light on the relationship between lipid membrane fluidity and various cellular functions, report scientists at Tokyo Institute of Technology and Kyushu University.

14 Mar 2024

Decoding the Secrets of Ribosome Recycling at the Endoplasmic Reticulum

Researchers from Stanford University and LMU have uncovered how cells renew their endoplasmic reticulum’s protein factories.

26 Feb 2024

Mayo Clinic Researchers Analyze Zombie Cells to Explain Aging

With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules.

16 Feb 2024

Relation Between Faulty DNA Disposal System and Inflammation

The path from mitochondrial stress to leaking endosomes to immune system initiation in mouse cells is outlined by Salk scientists, providing new therapeutic targets to potentially reduce inflammation in aging and disease.

12 Feb 2024

Scientists Unleash the Power of Calcium to Target and Destroy Tumor Cells

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.

30 Jan 2024

Study Shows How Obesity Causes Mitochondrial Fragmentation in Fat Cells

The number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic.

30 Jan 2024

The Role of Diffusion Barriers in Cellular Functions

According to a recent paper published in the “Journal of Cell Biology” by the Barral group (IBC), diffusion barriers are established by mitochondria independently of physical separation.

16 Jan 2024

Genetic Twist in Tiny Protein Protects Against Parkinson's

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

3 Jan 2024