Pathogen News and Research

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Using Mobile Data to Track the Spread and Evolution of Superbugs

Key insights into the global spread, evolution, and resistance patterns of a major bacterium causing pneumonia and meningitis have been revealed through the combination of genomic data and human travel patterns over 14 years in South Africa.

4 Jul 2024

Metabolic Priming of CAR T Cells for Treatment of Solid Tumors

A promising therapy that treats blood cancers by harnessing the power of the immune system to target and destroy cancer cells could now treat solid tumors more efficiently.

3 Jul 2024

Genomic Analysis Reveals Andean Origin and Colombian Migration Route for P. infestans

A recent study casts doubt on the widely held belief that Phytophthora infestans, the deadly potato blight pathogen, originated in Mexico.

2 Jul 2024

Discovery Reveals the Role of Interleukin-12 in Directing B-Cell Antibody Responses

B cells are known to generate antibodies through two different responses—an "emergency response" and an "everything is okay, let’s prepare for the future response," says Mark Shlomchik, UPMC Professor and Distinguished Professor of Immunology, University of Pittsburgh School of Medicine.

28 Jun 2024

New Tool IMPRINT Enhances DNA Transformation in Various Bacterial Strains

Bacteria, with their unique capabilities, hold immense promise for improving various aspects of the world.

27 Jun 2024

Study Reveals Immune Factors Behind COVID-19 Resistance in Some Individuals

As part of the first-ever COVID-19 human challenge study, researchers from the Wellcome Sanger Institute, University College London (UCL), Imperial College London, the Netherlands Cancer Institute, and their collaborators examined immune responses against SARS-CoV-2 infection in healthy adult volunteers using single-cell sequencing.

20 Jun 2024

The Link Between Climate Change and Drug-Resistant Fungal Infections

In a recent study on fungal diseases in Chinese hospitals, researchers discovered that two individuals were infected by a previously undocumented fungus affecting human health.

20 Jun 2024

St. Jude Researchers Discover NLRC5's Role in Inflammatory Cell Death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

17 Jun 2024

Exploring the Potential of Bacteriophages

Bacteriophages, viruses that target and destroy bacteria, are ubiquitous in the natural world. They play a crucial role in controlling microbe populations, though the mechanisms behind this regulation are not yet fully understood.

14 Jun 2024

Lung Organoids Shed Light on Pseudomonas aeruginosa's Invasive Tactics

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen.

11 Jun 2024

Cellular Architecture Dictates T Cell Fate in Immune Response

From the outside, most T cells look the same: small and spherical. Now, a team of researchers led by Berend Snijder from the Institute of Molecular Systems Biology at ETH Zurich has taken a closer look inside these cells using advanced techniques.

7 Jun 2024

New Microscopy Reveals Secrets of SARS-CoV-2 Replication

Recent research published in Nature Communications by a Stanford University team may provide more accuracy in drug development by examining at the nanoscale how the SARS-CoV-2 virus replicates in cells.

4 Jun 2024

Azoles Trigger Two Self-Destruction Pathways in Fungi

Scientists have shown that the most common class of antifungals used worldwide induces microorganisms to self-destruct.

4 Jun 2024

Study Uncovers Fungal Self-Destruct Mechanism

Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct.

3 Jun 2024

Integrative genomic study identifies two new potential drug targets in Mycobacterium tuberculosis

Researchers used existing whole genome sequences of M. tuberculosis and conducted a pangenomic analysis to identify potential drug targets.

28 May 2024

New Method Sheds Light on How Protein Modifications Power T Cells

Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit.

30 Apr 2024

Harmless Particles Enhance Immune Response, Study Finds

Our lungs are bombarded by all manner of different particles every single day. Whilst some are perfectly safe for us, others-;known as pathogens-;have the potential to make us ill.

29 Apr 2024