Pathophysiology News and Research

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Researchers discover new druggable pathway linked with tuberous sclerosis

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

25 Jun 2020

Genetic dysfunction of brain astrocytes promotes head pain in familial migraine

Neuroscientists of the University of Zurich shed a new light on the mechanisms responsible for familial migraine: They show that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence.

25 Jun 2020

Biochemical and computational methods for large-scale protein-arginine methylation analysis

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs).

23 May 2020

Genetic discoveries raise the promise of developing new treatments for schizophrenia

In recent years, genome-wide association studies have identified many different genetic variants associated with schizophrenia.

22 May 2020

Researchers identify missing component of innate immune signaling

How cells recognize pathogens and alert the immune system swiftly is a fundamental process of high importance for the survival of any species, including humans.

14 May 2020