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Intellegens and CPI Awarded £1.6 m Innovate UK Grant to Advance Manufacture of Oligonucleotide Therapeutics with Machine Learning

Intellegens today announced that it has secured a £1.6 m grant from Innovate UK, part of UK Research and Innovation (UKRI), to apply ML in the emerging field of oligonucleotide therapies.

From Intellegens Limited 30 Aug 2023

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

Oxidative stress, caused by an imbalance of free radicals and antioxidants, regularly reduces the yield of pharmaceuticals and therapeutics produced via bioprocessing by about 10-15%. Now, Xheme, Inc.'s Xheme Multifunctional Additive (XMA), a programmable non-toxic nanoporous microparticle, has demonstrated the ability to significantly reduce or eliminate the damage of oxidative stress in bioprocessing conditions.

25 Jul 2023

'Purecap' Technique Produces Highly Active mRNA Vaccines with Lower Immunostimulatory Activity

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

6 Jul 2023

New Study Sets the Stage to Help People Maintain Weight Loss After Dieting

Researchers led by McMaster University professor Gregory Steinberg and postdoctoral research fellow Dongdong Wang have uncovered a key mechanism for promoting weight loss and maintaining the burning of calories during dieting.

29 Jun 2023

Reengineering the Cellular Synthetic Machinery to Produce Never-Before-Seen Polymers

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals -; from fuels to fabrics and drugs -; beyond the normal repertoire of microbes.

14 Jun 2023

Electronic Nose Consistently Detects VOCs at Low Concentrations

Volatile organic compounds are chemicals emitted as gases that can have adverse health effects. They are often found in paints, pharmaceuticals, and refrigerants, among other common products, but they can also act as markers of explosives, insect infestation, food spoilage, and disease.

30 May 2023

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's Pain Research Center.

23 May 2023

Predictive Models to Determine the Structure, Stability, Flexibility and Biology of RNA-Targeted Drugs

Proteins are large, complex molecules that play many critical roles in the body and are produced following the instructions encoded in DNA.

18 May 2023

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow.

18 May 2023

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

12 May 2023

Revealing the Conserved Role of Serotonin in Maintaining Germline Quality

Worms may not be depressed. However, this does not prevent them from benefiting from antidepressants.

5 May 2023

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023

Mirror-Image Versions of a Small Molecule Pave New Way for Cancer Drug Discovery

Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs.

28 Apr 2023

UCF Scientists Develop a Digital Topographical Map of the Cardiac Sympathetic Neural Network

A team of UCF College of Medicine researchers has created a digital topographical map of the cardiac sympathetic neural network, the region that controls the body's heart rate and its "fight-or-flight" response.

18 Apr 2023

Research Identifies Protective Drugs that may Lessen the Collateral Damage Caused by Antibiotics

Antibiotics help to fight bacterial infections, but they can also harm the helpful microbes living in the gut, which can have long-lasting health consequences.

17 Apr 2023

Study Represents a Paradigm Shift in Renal Physiology/Mammalian Salt Handling

A new study led by Marshall University researchers focuses on a novel mechanism of the body's regulation of salt balance.

3 Apr 2023

New project addresses the lack of standards for optimal management of Lp(a)

According to a recent scientific statement gathered from American Heart Association, high levels of lipoprotein(a) [Lp(a)] are known to be a separate, chiefly inherited and causal risk factor for cardiovascular disease, known to be the leading cause of death and disability around the world.

29 Mar 2023

Pharmaceuticals News and Research

Intellegens and CPI Awarded £1.6 m Innovate UK Grant to Advance Manufacture of Oligonucleotide Therapeutics with Machine Learning

Bioprocessing Breakthrough: Xheme Non-Toxic, Multifunctional Additive Eliminates Oxidative Stress

'Purecap' Technique Produces Highly Active mRNA Vaccines with Lower Immunostimulatory Activity

New Study Sets the Stage to Help People Maintain Weight Loss After Dieting

Reengineering the Cellular Synthetic Machinery to Produce Never-Before-Seen Polymers

Electronic Nose Consistently Detects VOCs at Low Concentrations

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Predictive Models to Determine the Structure, Stability, Flexibility and Biology of RNA-Targeted Drugs

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Understanding How Cell-to-Cell Communication Networks Drive Pancreatic Cancer Development

Revealing the Conserved Role of Serotonin in Maintaining Germline Quality

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Mirror-Image Versions of a Small Molecule Pave New Way for Cancer Drug Discovery

UCF Scientists Develop a Digital Topographical Map of the Cardiac Sympathetic Neural Network

Research Identifies Protective Drugs that may Lessen the Collateral Damage Caused by Antibiotics

Study Represents a Paradigm Shift in Renal Physiology/Mammalian Salt Handling

New project addresses the lack of standards for optimal management of Lp(a)

Using viruses to fight antibiotic-resistant "superbugs"

Tardigrade proteins for significant advancement in human health

Delaying paralysis in ALS by using designer DNA drug

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Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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