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Researchers discover protein that may trigger lung scarring

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

18 Dec 2020

Drug meant for bacterial infections can combat weight gain

A drug originally developed to treat bacterial infections has proved capable of boosting the metabolism and attenuating the weight gain induced by a fatty diet in tests with mice. The study was conducted at the University of Campinas (UNICAMP) with FAPESP's support, and the findings have just been published in the journal Science Advances.

3 Dec 2020

Placental gene expression related to preeclampsia may be affected by vitamin D status

According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies. It can cause serious, sometimes fatal, complications in the mother and child.

10 Nov 2020

LipiDiDiet project shows positive effects of nutrient intervention in early Alzheimer’s disease

Trial participants who received a multinutrient formulation over an extended period of time showed a significantly less rapid deterioration in cognitive performance than the patients in a control group, who received only a placebo.

6 Nov 2020

New antibodies could form the basis of a broad-spectrum flu drug

Researchers have identified two antibodies that protect mice against lethal infections of influenza B virus, report scientists at Washington University School of Medicine in St. Louis and Icahn School of Medicine at Mount Sinai.

25 Sep 2020

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

New data presented at ESMO 2020 have shown that immunotherapy is beneficial for patients with gastric and esophageal cancers who currently have poor survival. (1-3)

24 Sep 2020

Combination regimen improves overall survival in acute myeloid leukemia patients

A combination regimen of venetoclax and azacitidine was safe and improved overall survival (OS) over azacitidine alone in certain patients with acute myeloid leukemia (AML), according to the Phase III VIALE-A trial led by The University of Texas MD Anderson Cancer Center.

13 Aug 2020

Aspirin may increase risk of disease progression in older adults with advanced cancer

Results from a recent clinical trial indicate that for older adults with advanced cancer, initiating aspirin may increase their risk of disease progression and early death.

11 Aug 2020

COVID-19 Prevention Network announces two trials to evaluate monoclonal antibodies

The COVID-19 Prevention Network (CoVPN) today announced two Phase 3 trials to determine whether monoclonal antibodies (mAbs) can prevent SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2020

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

5 Aug 2020

Rapid drug development yields potential treatment for yellow fever

Yellow fever, a hemorrhagic disease that is common in South America and sub-Saharan Africa, infects about 200,000 people per year and causes an estimated 30,000 deaths.

From Massachusetts Institute of Technology (MIT) 30 Jul 2020

Fusion protein found to effective at treating pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is an insidious disease. Symptoms may begin slowly, and even before they appear, extensive damage has caused the obstruction of small arteries leading to increased blood pressure in the lungs.

22 Jul 2020

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

From The University of California, Davis 21 Jul 2020

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

Keck Medicine of USC physicians are enrolling patients as part of an international clinical trial to evaluate the safety and efficacy of an antiviral drug, DAS181, as a possible treatment for hospitalized patients with severe COVID-19.

15 Jul 2020

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

Research has shown that the tumor microenvironment (TME) can help cancers grow and evade the immune response.The TME has even been shown to inhibit cellular immunotherapy, a novel form of treatment in which the cells of a patient's immune system are re-engineered in the lab to attack cancer cells.

14 Jul 2020

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.

14 Jul 2020

Single dose of flu drug can limit the spread of the illness within households

A single dose of the flu drug baloxavir marboxil can reduce the spread of the illness within households, new research concludes.

14 Jul 2020

Feed additive shows promise to mitigate enteric methane emissions in dairy cows

The enteric methane mitigation potential of 3-nitrooxypropanol (3-NOP) has been confirmed in previous studies. 3-NOP is highly soluble and rapidly metabolized in the rumen.

25 Jun 2020

New microscope looks at the different parameters that change during wound healing

Researchers at the GSK Center for Optical Molecular Imaging have developed a new microscope that looks at the different parameters that change during wound healing. They hope to use this technique to understand how skin disorders, such as foot ulcers in diabetic patients and psoriasis, can be treated.

18 Jun 2020

BCG vaccine elicits trained immunity in humans

A tuberculosis vaccine developed 100 years ago also makes vaccinated persons less susceptible to other infections.

16 Jun 2020

Placebo News and Research

Researchers discover protein that may trigger lung scarring

Drug meant for bacterial infections can combat weight gain

Placental gene expression related to preeclampsia may be affected by vitamin D status

LipiDiDiet project shows positive effects of nutrient intervention in early Alzheimer’s disease

New antibodies could form the basis of a broad-spectrum flu drug

New data shows immunotherapy is beneficial for patients with gastric, esophageal cancers

Combination regimen improves overall survival in acute myeloid leukemia patients

Aspirin may increase risk of disease progression in older adults with advanced cancer

COVID-19 Prevention Network announces two trials to evaluate monoclonal antibodies

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

Rapid drug development yields potential treatment for yellow fever

Fusion protein found to effective at treating pulmonary arterial hypertension

UC Davis Health tests new antibody combination as potential treatment for COVID-19

Keck Medicine of USC participates in clinical trial to test antiviral drug as potential COVID-19 treatment

Nano-radiomics uses imaging data to assess changes in the tumor microenvironment

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

Single dose of flu drug can limit the spread of the illness within households

Feed additive shows promise to mitigate enteric methane emissions in dairy cows

New microscope looks at the different parameters that change during wound healing

BCG vaccine elicits trained immunity in humans

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