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New AI Tool Predicts Protein Behavior in Cellular Context

A fish on land can still wave its fins, but the outcomes are very different when the creature is in water. The comparison, attributed to prominent computer scientist Alan Kay, is used to demonstrate the importance of context in clarifying research issues.

19 Aug 2024

The Importance of Antioxidant Therapy in Preventing Parkinson's Disease

The neurodegenerative condition known as Parkinson's disease is caused by the death of neurons that generate dopamine, a neurotransmitter essential for both motor control and cognitive function.

6 Aug 2024

Mucus-Based Bioink Shows Promise for 3D-Printed Lung Tissue

Each year, lung illnesses claim the lives of millions of people worldwide. There are few available treatments, and animal models used to research these conditions and potential drugs are insufficient. Researchers have now successfully developed a mucus-based bioink for 3D printing lung tissue.

31 Jul 2024

New Study Reveals Microbial Succession Patterns in Shibazuke Fermentation Process

Shibazuke is a traditional Japanese eggplant pickle produced by the process of fermentation using lactic acid bacteria (LAB).

29 Jul 2024

"AnoxyGen" Project Aims to Unlock the Untapped Biosynthetic Potential of Anaerobes

The “AnoxyGen” project will decode novel active substances of anaerobes and elucidate their role in nature. Some of these could be useful for humans, animals and the environment.

15 Jul 2024

UCL Study Uncovers Astrocytes' Role in Brain Energy Boosting Mechanism

A key mechanism which detects when the brain needs an additional energy boost to support its activity has been identified in a study in mice and cells led by UCL scientists.

4 Jul 2024

Researchers Decode Impact of Every Possible Alteration in Critical Cancer Gene

Scientists at the Francis Crick Institute have mapped all possible outcomes of changes to a tumor-suppressing gene called VHL, as the first step in a massive research project to unravel the consequences of tens of thousands of genetic variations in genes linked to cancer.

4 Jul 2024

Study Finds Bacteria in Commercial Tattoo and Permanent Makeup Inks

Commercial tattoo and permanent makeup inks have been found to contain both aerobic and anaerobic bacteria by researchers.

3 Jul 2024

New Antioxidants Show Promise for Broader Cellular Protection

Professor José Villalaín at Miguel Hernández University of Elche (UMH) is searching for improved antioxidants.

3 Jul 2024

Study Reveals Epigenetic Changes in Sperm from Non-Genetic Infertility Causes

How non-genetic factors can induce epigenetic modifications to the sperm and cause male infertility.

3 Jul 2024

High-Pressure Processing Revolutionizes Food And Pharmaceutical Industries

How high pressure impacts protein structure, unfolding, refolding, and crystallization.

1 Jul 2024

New Hypothesis Links Firefly Bioluminescence to Oxygen Levels

A genomic analysis disproved the popular theory regarding the origin of firefly lights.

26 Jun 2024

3D Cell Cultures Improve Drug Screening Accuracy but Show Lower Efficacy for Anti-Cancer Drugs

The existing knowledge on monolayers and spheroid-based cell cultures, including the constituent compounds, and the difference in efficacy during drug screening, especially for anti-cancer drugs targeting cytoskeletal dynamics and cell cycles.

21 Jun 2024

Enzymes Replace Cyanide in Eco-Friendly Nitrile Synthesis

If the household cleaner emits a lemon-like odor, it may be due to a nitrile called citronellyl nitrile. Chemical-resistant gloves, superglue, and active pharmaceutical ingredients are all made with these adaptable chemical nitrile groups.

19 Jun 2024

Bacterial Buckling: Filamentous Cyanobacteria Bend Under Pressure

Filamentous cyanobacteria buckle at a certain length when they encounter an obstacle. This was discovered by the research group of Stefan Karpitschka, group leader at the Max Planck Institute for Dynamics and Self-Organization and professor at the University of Konstanz.

17 Jun 2024

St. Jude Researchers Discover NLRC5's Role in Inflammatory Cell Death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

17 Jun 2024

New Clinical Trial Offers Path to Sickle Cell Cure

The most recent results from a clinical trial were given by researchers in an effort to find a cure for sickle cell disease, a painful genetic blood illness that has few available treatments.

17 Jun 2024

Unveiling the Chemical Secrets of Coral Reefs and Insights into Marine Health

What species exist on this coral reef, and how healthy are they?

7 Jun 2024

LoCoHD: A Novel Method for Comparative Protein Structure Analysis

In a paper recently published in Nature Communications, the HUN-REN-ELTE Protein Modeling Research Group (Institute of Chemistry) has laid the foundations for a mathematical method, allowing the computer-assisted comparison of the three-dimensional structures of proteins.

30 May 2024

Mitochondrial Phosphate Carrier MIR1: A Key Player in Candida albicans Virulence

This study is led by Professor Yan Wang (School of Pharmacy, Second Military Medical University (Naval Medical University), Shanghai, China). Her team found that the lack of MIR1 gene, which encodes mitochondrial phosphate carrier, can lead to severe virulence defects in Candida albicans.

23 May 2024