therapeutics News and Research

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Using 3D mapping techniques to unravel mystery of blood stem cells

Princess Margaret scientists have revealed how stem cells are able to generate new blood cells throughout our life by looking at vast, uncharted regions of our genetic material that hold important clues to subtle biological changes in these cells.

26 Nov 2020

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 26 Nov 2020

Researchers identify promising treatments for late-onset Alzheimer’s disease

Scientists from The Mount Sinai Hospital and the National Center for Geriatrics and Gerontology based in Japan have recently discovered novel molecular mechanisms that drive late-onset Alzheimer’s disease (LOAD).

25 Nov 2020

Researchers look for mechanisms that stabilize or destabilize key sections of biomolecules

Knowing precisely where proteins are frustrated could go a long way toward making better drugs. That's one result of a new study by Rice University scientists looking for the mechanisms that stabilize or destabilize key sections of biomolecules.

24 Nov 2020

New research opens up potential target for treating bone disorders

New research has discovered a cell type that governs the way bones form and maintain themselves, opening up a potential target for future therapies for bone disorders like osteoporosis.

23 Nov 2020

Gaining new insights into bacterial pneumonia

Jacqueline Kimmey speaks to AZoLifeSciences about her research into bacterial pneumonia and the genes that drive its spread from the lungs into the blood.

From University of California Santa Cruz 23 Nov 2020

Tau protein in Alzheimer's disease looks different at every dementia stage

Research into Alzheimer's disease has long focused on understanding the role of two key proteins, beta amyloid and the tau protein. Found in tangles in patients' brain tissue, a pathological form of the tau protein contributes to propagating the disease in the brain.

19 Nov 2020

Scientists expand Darwin's evolutionary theory to include "molecular Darwinism"

Darwin's theory of evolution should be expanded to include consideration of a DNA stability "energy code" - so-called "molecular Darwinism" - to further account for the long-term survival of species' characteristics on Earth, according to Rutgers scientists.

From Rutgers University 17 Nov 2020

Genetic signature in localized prostate cancer can predict likelihood of tumor metastases

Researchers have identified a genetic signature in localized prostate cancer that can predict whether the cancer is likely to spread, or metastasize, early in the course of the disease and whether it will respond to anti-androgen therapy, a common treatment for advanced disease.

11 Nov 2020

Scientists identify potential targets against coronavirus

Scientists comprehensively studied the RNA genomic structure of the SARS-CoV-2 coronavirus.

11 Nov 2020

Mutations in SARS-CoV-2 spike protein may improve monoclonal antibody resistance

A recent paper examines a mutation of the spike protein of SARS-CoV-2 that has been observed to have arisen independently twice.

10 Nov 2020

Study shows how coronavirus block cells’ ability to produce protective proteins

One of the novel coronavirus' most insidious tricks is that it can block the ability of cells to produce protective proteins without hindering its own ability to replicate.

6 Nov 2020

Study sheds new light on key protein implicated in tumor development

A study headed by the University of Colorado Boulder has revealed a specific protein that is crucial for regulating the growth, proliferation, and function of cells, and how these cells were long implicated in the development of tumors.

5 Nov 2020

Researchers identify a new solution for treating ligament injuries

Ligament injuries that affect scores of regular citizens and athletes are sidelined every year. Added to this, recovery is painful and takes a long time and, at times, a return to normal function is never achieved because of the formation of scars—an aspect that makes ligament injuries inclined to more damage.

4 Nov 2020

Pancreatic cancer cells avert starvation by signaling to nerves, shows study

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online on November 2 in Cell.

3 Nov 2020

Study reveals proteins that enable SINEUPs to increase protein production

Scientists from an international group led by the RIKEN Center for Integrative Medical Sciences and Yokohama City University have discovered that a pair of proteins play a key role in allowing an important type of functional non-coding RNA, known as SINEUPs, to act to promote their target messenger RNA.

2 Nov 2020

Research projects receive BTCA awards to develop new drugs

Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.

From Harvard Medical School 30 Oct 2020

Scientists discover link between two signaling pathways crucial to growth of colon cancer

In breakthrough colon cancer research, scientists at ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a link between two key signaling pathways crucial to the development and growth of colon cancer. The study is published today in the journal PLOS ONE.

29 Oct 2020

RNA-centric mechanism regulates microRNAs linked to cancer, neurological disorders

MicroRNAs are small non-coding RNAs—that is, bits of genetic code that act as key gene regulators in various aspects of biological processes.

28 Oct 2020

Experimental vaccine shows promise for treating and preventing cancer in mice

An experimental vaccine, designed to enlist the body's own immune system to target cancer cells, has shown promise for treating and preventing cancer in mice.

23 Oct 2020