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Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center.

8 Dec 2020

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

According to a new study, a novel T cell genetically engineered by scientists from The University of Arizona Health Sciences can target and attack pathogenic T cells that are responsible for causing Type 1 diabetes. These latest findings may result in new immunotherapy therapies.

7 Dec 2020

Study examines impacts of widespread ocean pollution on human health

Ocean pollution is widespread and getting worse, and when toxins in the oceans make landfall they imperil the health and well-being of more than 3 billion people, according to a new report by an international coalition of scientists led by Boston College's Global Observatory on Pollution on Health and the Centre Scientifique de Monaco, supported by the Prince Albert II of Monaco Foundation.

4 Dec 2020

Researchers use wheat starch hydrogels to produce food by 3D printing

It is already possible to produce food with a 3D printer, potentially delivering products that suit consumer preferences regarding taste, texture, cost, convenience, and nutrition.

4 Dec 2020

Researchers determine role of NLRP1 protein in detecting the common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

From Nanyang Technological University Singapore (NTU Singapore) 3 Dec 2020

Could there be harmful chemicals in your household dust?

In this interview, AZoLifeSciences spoke to Dr. Atanu Sarkar to find out what potentially harmful chemicals could be lurking in your home.

From Memorial University 27 Nov 2020

CAR T cells display signs of efficacy against hard-to-treat pediatric cancer in phase 1 trial

A phase 1 trial involving 12 children with relapsed neuroblastoma - a hard-to-treat pediatric cancer - shows that anticancer CAR T cells displayed signs of efficacy against these tumors while avoiding damage to nerve tissue.

26 Nov 2020

Researchers identify new gene involved in neurodevelopmental disorders

Researchers and physicians constantly search for novel disease genes that can allow them to figure out why medical problems are not diagnosed in patients.

24 Nov 2020

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Scientists have successfully utilized a novel stem cell technology to examine the skin, specific to a group of living patients, in laboratory settings.

24 Nov 2020

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

Immune-system T cells have been reprogrammed into regenerative stem cell-like memory (TSCM) cells that are long-lived, highly active "super immune cells" with strong antitumor activity, according to new research from Georgetown Lombardi Comprehensive Cancer Center.

24 Nov 2020

MMR vaccine may be protective against COVID-19, study shows

The measles-mumps-rubella (MMR) vaccine has been theorized to provide protection against COVID-19. In a new study published in mBio, an open-access journal of the American Society for Microbiology, researchers provide further proof of this by showing that mumps IgG titers, or levels of IgG antibody, are inversely correlated with severity in recovered COVID-19 patients previously vaccinated with the MMR II vaccine produced by Merck. MMR II contains the Edmonston strain of measles, the Jeryl Lynn (B-level) strain of mumps, and the Wistar RA 27/3 strain of rubella.

23 Nov 2020

Finding ways to tackle food allergies at the source

Food allergies are a big problem. About 7% of children and 2% of adults in the U.S. suffer from some kind of food allergy.

19 Nov 2020

Study shows CRISPR/Cas9 system can effectively treat metastatic cancers

Researchers have shown that the advanced CRISPR/Cas9 system is extremely effective in curing metastatic cancers.

19 Nov 2020

Study reveals metabolic signaling pathways that influence key immune cells

Effector regulatory T cells, also known as eTreg cells, are a specialized subset of white blood cells that maintain the immune system.

18 Nov 2020

Somatic mutation acts as natural gene therapy in patients with GATA2 deficiency

Researchers affiliated with the Center for Cell-Based Therapy (CTC) in Ribeirão Preto, Brazil, have identified for the first time a non-hereditary mutation in blood cells from a patient with GATA2 deficiency, a rare autosomal disease caused by inherited mutations in the gene that encodes GATA-binding protein 2 (GATA2).

18 Nov 2020

Children News and Research

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

Study examines impacts of widespread ocean pollution on human health

Researchers use wheat starch hydrogels to produce food by 3D printing

Researchers determine role of NLRP1 protein in detecting the common cold virus

Could there be harmful chemicals in your household dust?

CAR T cells display signs of efficacy against hard-to-treat pediatric cancer in phase 1 trial

Researchers identify new gene involved in neurodevelopmental disorders

Scientists use new technology to observe DNA defects in children with Fanconi anemia

Study: Benefits of immunotherapy can be improved by boosting stem cell activity

MMR vaccine may be protective against COVID-19, study shows

Finding ways to tackle food allergies at the source

Study shows CRISPR/Cas9 system can effectively treat metastatic cancers

Study reveals metabolic signaling pathways that influence key immune cells

Somatic mutation acts as natural gene therapy in patients with GATA2 deficiency

Discovery of 'Achilles heel' in protein crucial to HIV virulence paves way for new drugs

Bacterial microbes in the human gut could help diagnose and treat autism spectrum disorder

Food insecurity in America reached an all-time high during COVID-19

Exposure to air pollution during fetal period may contribute to higher blood pressure

Fruit and vegetable supply in the UK relies on imports from climate-vulnerable countries

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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