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Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

Space travel has always tested the human body by the effects of the new conditions of altered gravity on biological systems.

8 Mar 2023

LDL-mediated nanoparticle drug delivery could potentially circumvent high-grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

8 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Study links neutral maternal behavior toward infants with epigenetic change in children

Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response.

3 Mar 2023

Innovative method to quickly identify bacteria in fluids

Shine a laser on a drop of blood, mucus, or wastewater, and the light reflecting back can be used to positively identify bacteria in the sample.

3 Mar 2023

Researchers provide an entirely new perspective on tissue oxygenation

Cardiovascular medicine, hematology and pulmonary medicine may soon have the first-ever therapies to correct poor tissue oxygenation, a key driver of disease in millions, including peripheral artery disease, sickle cell disease, heart failure, stroke, emphysema and many others.

2 Mar 2023

Stress response in mom leads to epigenetic change in children

Adding evidence to the importance of early development, a new study links neutral maternal behavior toward infants with an epigenetic change in children related to stress response.

2 Mar 2023

New signals of natural selection in humans identified

A team of global experts has discovered new signals of natural selection in humans.

2 Mar 2023

Novel way to block the death of nerve cells in MND

Scientists have found a novel way to block the transportation of mutant RNA and subsequent production of toxic repeat proteins which lead to the death of nerve cells in the most common subtypes of motor neurone disease (MND) and frontotemporal dementia (FTD).

2 Mar 2023

Cell therapy trial promises long-term improvement for patients with chronic heart failure

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

28 Feb 2023

New method can rapidly detect COVID-19 infections with near-perfect accuracy

By inspecting the body's immune response at a molecular level, a research team has developed a new way to test patients for COVID-19.

28 Feb 2023

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

A tumor's necrotic core contains factors that appear to promote metastasis, or the seeding of tumors cells throughout the body, according to a new study in rats by researchers at Fred Hutchinson Cancer Center.

28 Feb 2023

Artificial BBB model can help determine how well antibody-based therapies can enter the brain

A research group at Uppsala University has developed a simple and effective artificial blood-brain barrier model that can be used to determine how well antibody-based therapies can enter the brain.

27 Feb 2023

Study: Oral verapamil improves the pancreas' insulin secretion in children with newly-diagnosed TID

Published in JAMA, a University of Minnesota led study shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes (T1D).

27 Feb 2023

New model simplifies the understanding of vascular malformations

Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood.

27 Feb 2023

Synthetic hydrogels provide an effective scaffold for brain tissue growth

Synthetic hydrogels were shown to provide an effective scaffold for neuronal tissue growth in areas of brain damage, providing a possible approach for brain tissue reconstruction.

24 Feb 2023

Researchers tease apart the molecular components involved in abdominal aneurysms

When the artery that supplies the stomach and the liver forms a bulge that ruptures, this medical emergency results in the deaths of 50 percent of patients before they reach the hospital.

24 Feb 2023

Prototype treatment shows great potential in neutralizing snake toxins from multiple species

Prototype treatment for snake bite envenoming proves effective against the venom of African and Asian elapid snakes, such as some cobra, mamba, and krait species, new research shows.

24 Feb 2023

Deep-learning approach to achieve faster and high-resolution photoacoustic computed tomography

It takes a few moments for the sound of thunder to reach our ears after a flash of lightning. This phenomenon is due to the photoacoustic (PA) effect where materials near the lightning instantly expand as the optical energy of the lightning is absorbed and converted into thermal energy.

24 Feb 2023

Blood News and Research

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Short exposure to altered gravity does not alter leukocyte immunophenotyping and functional capacity

LDL-mediated nanoparticle drug delivery could potentially circumvent high-grade gliomas

Using nanoparticles to carry drugs across the blood-brain barrier

Study links neutral maternal behavior toward infants with epigenetic change in children

Innovative method to quickly identify bacteria in fluids

Researchers provide an entirely new perspective on tissue oxygenation

Stress response in mom leads to epigenetic change in children

New signals of natural selection in humans identified

Novel way to block the death of nerve cells in MND

Cell therapy trial promises long-term improvement for patients with chronic heart failure

New method can rapidly detect COVID-19 infections with near-perfect accuracy

Experts reveal the link between necrosis, circulating tumor cells, and cancer metastasis

Artificial BBB model can help determine how well antibody-based therapies can enter the brain

Study: Oral verapamil improves the pancreas' insulin secretion in children with newly-diagnosed TID

New model simplifies the understanding of vascular malformations

Synthetic hydrogels provide an effective scaffold for brain tissue growth

Researchers tease apart the molecular components involved in abdominal aneurysms

Prototype treatment shows great potential in neutralizing snake toxins from multiple species

Deep-learning approach to achieve faster and high-resolution photoacoustic computed tomography

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