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Yeast platform for the production of plant-derived anti-cancer drug

The supply of a plant-derived anti-cancer drug can finally meet global demand after a team of scientists from Denmark and the U.S. engineered yeast to produce the precursor molecules, which could previously only be obtained in trace concentrations in the native plant.

1 Sep 2022

A “stress test” with a previously unknown gene to revive the exhausted T cells

The task of battling cancer cells can fatigue T cells employed in immunotherapy treatments, or they could shut down once they penetrate tumors. Researchers at the Gladstone Institutes and UC San Francisco have strengthened the therapeutic cells’ resistance via a CRISPR-based edit on their genomes.

30 Aug 2022

Study explains the dynamics underlying liver damage

The immune system may attack the liver when fat builds up there. The chemical that triggers these responses has been discovered by Weill Cornell Medicine researchers in a recent study, and this information helps to explain the dynamics of liver damage that can accompany type 2 diabetes and obesity.

23 Aug 2022

New method identifies human gut microbes that contribute to inflammatory diseases

Researchers at Cedars-Sinai have created a way to determine the human gut microorganisms that are most likely to cause a variety of inflammatory disorders, including obesity, liver disease, inflammatory bowel disease, cancer, and several neurological conditions.

22 Aug 2022

BIDMC researchers develop a transformative approach to make more of beige adipose tissues

Once considered an inert tissue, fat – or adipose tissue – is now known to play an active role in the body's critical functions by secreting hormones that regulate hunger and body temperature.

18 Aug 2022

Mayo Clinic's strategic collaboration in biomanufacturing focuses on delivering novel biotherapeutics

Mayo Clinic today announced a strategic collaboration in biomanufacturing to deliver novel biotherapeutics for rare and complex conditions.

17 Aug 2022

New type of chip could lead to earlier and more targeted treatment for cancer

Cancer spreads via circulating tumor cells (CTCs) that travel through the blood to other organs, and they are nearly impossible to track.

17 Aug 2022

Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

16 Aug 2022

Researchers face challenges with stem cell lines that carry major DNA damage

Stem cells are a type of cell that can be configured to transform into almost any sort of cell in the body. They are presently used in research on organ development as well as in the initial phases of embryo development.

15 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

Study provides guidelines on how to design safer CRISPR reagents

The 2020 Nobel Prize in Chemistry was awarded to Jennifer A. Doudna and Emmanuelle Charpentier for developing the widely utilized and incredibly precise genome editing method known as CRISPR/Cas9

11 Aug 2022

Circadian clocks involve primarily in fat cell growth

According to two studies conducted by researchers at Weill Cornell Medicine, the circadian clocks that keep the body and its cells synchronized to the 24-hour day-night cycle are severely disrupted.

9 Aug 2022

Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

An antibody that is successfully used to treat a variety of tumors has been replaced with a tiny molecule that researchers from Tel Aviv University and the University of Lisbon have jointly found and manufactured.

9 Aug 2022

Researchers create CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells taken from the patient’s own blood are modified to contain so-called chimeric antigen receptors (CAR), which provide the T cells the ability to target and eradicate tumor cells.

8 Aug 2022

Mitochondrial DNA plays a crucial role in inflammation, study finds

Mitochondria are generally known as the powerhouse of the cell, however, growing research indicates that they may potentially be involved in inflammation.

8 Aug 2022

Research findings likely to help identify key differences between effective and flawed immune systems

T cells, a special class of white blood cells, defend the body and kill infected or foreign tissue. In an organ called the thymus, they learn to distinguish between proteins that are helpful and those that are harmful.

8 Aug 2022

SLFN11’s surveillance part in protein homeostasis

On July 25th, 2022, a new study perspective called “SLFN11’s surveillance role in protein homeostasis” was published in Volume 9 of Oncoscience.

8 Aug 2022

Active immune cells provide great protection against ischemic stroke

According to research published today in the Journal of Clinical Investigation by neurologists and immunologists at the University of Pittsburgh, a special subgroup of white blood cells provides mice with quick-acting and long-lasting protection against ischemic stroke.

From University of Pittsburgh 3 Aug 2022

Novel model system to identify new treatments for CF patients who continue to struggle without therapies

A mutation in the CFTR gene results in cystic fibrosis (CF). Despite the fact that there are many hundreds of identified mutations, not all of them can now be treated, leaving a sizable portion of CF patients without access to targeted medicines.

3 Aug 2022

Scientists develop microscopy technology that observes how new neurons struggle to reach their developmental destination

With organoids to model early growth, scientists employed a developing microscopy technology to observe that new neurons find it hard to reach their developmental goal.

From Massachusetts Institute of Technology (MIT) 1 Aug 2022

Blood News and Research

Yeast platform for the production of plant-derived anti-cancer drug

A “stress test” with a previously unknown gene to revive the exhausted T cells

Study explains the dynamics underlying liver damage

New method identifies human gut microbes that contribute to inflammatory diseases

BIDMC researchers develop a transformative approach to make more of beige adipose tissues

Mayo Clinic's strategic collaboration in biomanufacturing focuses on delivering novel biotherapeutics

New type of chip could lead to earlier and more targeted treatment for cancer

Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

Researchers face challenges with stem cell lines that carry major DNA damage

Mount Sinai and Regeneron Genetics Center launch a large-scale genome sequencing project

Study provides guidelines on how to design safer CRISPR reagents

Circadian clocks involve primarily in fat cell growth

Researchers report the identification of novel small molecules that stimulate human adaptive immune responses

Researchers create CAR T cells for cancer immunotherapy

Mitochondrial DNA plays a crucial role in inflammation, study finds

Research findings likely to help identify key differences between effective and flawed immune systems

SLFN11’s surveillance part in protein homeostasis

Active immune cells provide great protection against ischemic stroke

Novel model system to identify new treatments for CF patients who continue to struggle without therapies

Scientists develop microscopy technology that observes how new neurons struggle to reach their developmental destination

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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