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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

More Genes Changed By Early Life Stress Than Head Injury

Researchers recently discovered a phenomenon as they delved into the investigation of whether early-life stress exacerbates the impact of a childhood head injury on health and behavior in later years.

16 Nov 2023

Tokyo Metropolitan University Decodes DNA Repair Mechanisms

Tokyo Metropolitan University researchers have uncovered crucial aspects of the DNA repair mechanism within human bodies.

16 Nov 2023

Study Sheds Light on Factors Contributing to Low-Level Viremia in HIV Patients

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

15 Nov 2023

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

LJI Scientists Uncover New Superpower of MAIT Cells

Scientists at La Jolla Institute for Immunology (LJI) are investigating a talented type of T cell.

13 Nov 2023

Examining the Link Between Sleep Alteration and Aging in Jewel Wasps

Parents of newborns might sense a rapid aging effect during the early months of sleepless nights. Currently, researchers at the University of Leicester are exploring the intriguing possibility that the key to a long and healthy life lies in a restful night's sleep and human DNA.

10 Nov 2023

New Insights Into Tumor-Immune Interactions Could Lead to More Effective Therapies for Multiple Myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

10 Nov 2023

Seventh Annual NSF-Funded Solicitation for Tissue Engineering Research Utilizing the ISS National Lab Now Open

For the seventh consecutive year, the U.S. National Science Foundation (NSF) is funding a solicitation seeking projects that utilize the International Space Station (ISS) National Laboratory to advance tissue engineering and mechanobiology research. Through this solicitation, NSF will provide up to $1.6 million in funding for multiple projects intending to leverage the orbiting laboratory.

10 Nov 2023

Unleashing the Power of Melanin in Space for Next-Gen Biomaterials

Exploring the mysteries of the natural pigment melanin in the unique microgravity environment of the International Space Station (ISS) could lead to groundbreaking advances in biomaterial production on Earth and beyond.

9 Nov 2023

Challenging the Assumption of Genetic Homogeneity in European Ancestry

Previous studies studying the genomes of people with European heritage might have reported misleading results because they did not adequately account for population structure, according to a new study.

8 Nov 2023

Distinctive Taste Receptors Between a Moth’s Larval and Adult Stages

New research reveals that the cotton bollworm (Helicoverpa armigera) employs distinct sugar-sensing mechanisms in its larval and adult stages to fulfill its dietary preferences.

8 Nov 2023

SPT5 Identified as a Potential Target Protein for Treatment of MYC-Dependent Cancers

MYC proteins play an important role in many types of cancer. A research team at the University of Würzburg has now succeeded in indirectly influencing these proteins - with clear consequences for the tumor.

8 Nov 2023

Research Reveals the Genetic Basis for Song Sparrow Adaptation to Local Climate

Whole genome sequencing of North American song sparrows has revealed the genetic underpinnings for a stunning range of body sizes found throughout the bird's westernmost range-;an adaptation that may make the birds more resilient to climate change.

8 Nov 2023

Unlocking the Secrets of Bacterial Transcription

Bacterial transcription serves as an assembly line for duplicating genetic directives from double-stranded DNA into RNA molecules.

7 Nov 2023

Unraveling the Mysteries of Tar Spot Disease in Corn

In 2015, the first instances of tar spot were reported, marking the emergence of a devastating disease in corn.

7 Nov 2023

Epidemiology and Genetic Underpinnings of Clonal Hematopoiesis

A comprehensive new study from deCODE genetics, a subsidiary of Amgen, published today in Nature Genetics, provides insights into the epidemiology and somatic and germline genetics of clonal hematopoiesis.

7 Nov 2023

Epigenetic Changes Drive Cancer Development

Every cell makes its own proteins by accessing the genetic information on its genes. Changes in this information, called mutations, may ruin the function of the affected proteins.

7 Nov 2023

Novel Gene Therapy Targets Core Motor Symptoms of Parkinson’s Disease

A team of researchers from the Shenzhen Institute of Advanced Technology (SIAT) at the Chinese Academy of Sciences (CAS) and their collaborators have devised a gene therapy approach aimed at selectively manipulating the affected circuitry in Parkinson’s disease.

6 Nov 2023