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Optimized nano-micelles can induce efficient genome editing in mouse brain

A research team has reported that improved nano-micelles can trigger efficient genome editing in the mouse brain.

15 Mar 2021

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

10 Mar 2021

New technique can mitigate the effects of brain injury in preterm babies

One in 10 babies are born prematurely in the United States, leading to complications that can impact the infants’ locomotor development and affect basic tasks.

9 Mar 2021

Catechin-type flavonoid compounds in tea relax blood vessels by activating ion channel proteins

A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall.

9 Mar 2021

Study reveals process behind key cellular change in amyotrophic lateral sclerosis

A research team has discovered the trigger of a crucial cellular change in amyotrophic lateral sclerosis (ALS)—a form of motor neuron disease.

5 Mar 2021

Neuronal and glial circuits form loosely coupled super-network within the brain

Tohoku University scientists have shown that neuronal and glial circuits form a loosely coupled super-network within the brain.

25 Feb 2021

New platform could help treat neurodegenerative diseases using regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

Longevity gene contributes to brain health during aging

According to a new study, a gene associated with an exceptionally long-life span in human beings guards the brain stem cells against the adverse effects of stress.

23 Feb 2021

First-in-human clinical trial to test safety, efficacy of gene therapy for Alzheimer's disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

From UC San Diego 19 Feb 2021

Proprioceptive neurons perform sensory functions in all human body movements

Scientists have unveiled a range of proprioceptive neurons and have uncovered a new form of plasticity, indicating neuronal individuality in the nervous system.

16 Feb 2021

Natural compounds in apples and other fruits may improve brain function

According to a new study, apples and other fruits contain natural substances that may help trigger the generation of new neurons in the brain.

15 Feb 2021

Tiny population of neurons may play a significant role in depression

A tiny population of neurons known to be important to appetite appear to also have a significant role in depression that results from unpredictable, chronic stress, scientists say.

12 Feb 2021

Enzyme in fruit fly larvae plays key role in waking up brain stem cells

Researchers studying an enzyme in fruit fly larvae have found that it plays an important role in waking up brain stem cells from their dormant 'quiescent' state, enabling them to proliferate and generate new neurons.

12 Feb 2021

Study may lead to alternative treatment for potentially addictive opioid pain killers

When two naturally occurring lipids are altered using a process called epoxidation, they are transformed into powerful agents that target numerous cannabinoid receptors in neurons, disrupting pathways that promote inflammation and pain.

11 Feb 2021

Scientists identify mystery protein that explains the origins of Parkinson's Disease

Researchers have made a “vital step” toward inferring the origins of Parkinson’s disease—a neurological condition that is rapidly growing in the world.

11 Feb 2021

Light-activated protein can be used to study single synapses of neurons

Neurons are the primary cells of the nervous system, and the signals that are transmitted between them are responsible for all our actions and our cognitive ability.

10 Feb 2021

Scientists implicate disruption in prenatal neurogenesis in the development of autism

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

9 Feb 2021

Study provides a causal link between the Alzheimer's risk gene and COVID-19

A City of Hope-led research team found that the same gene that increases the risk for Alzheimer's disease, ApoE4, can increase the susceptibility to and severity of COVID-19.

5 Feb 2021

Ancestral backgrounds can influence Alzheimer's disease risk, finds study

Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele.