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Curcumin could enhance ovarian cancer treatments

A pharmacology researcher at New York Institute of Technology College of Osteopathic Medicine (NYITCOM) has co-authored a new study that makes a strong case for why a golden spice commonly found in curry could enhance ovarian cancer treatments.

23 Mar 2023

Using viruses to fight antibiotic-resistant "superbugs"

The Centers for Disease Control and Prevention warns that the increase in cases of the drug-resistant bacterial infection Shigella could be a predictor of what's to come for other bacteria.

22 Mar 2023

How can the adoption of AI technology accelerate drug discovery?

In this interview, we speak to SLAS 2023 keynote speaker Joshua Smith from IBM Research about the importance of AI in accelerating drug discovery.

From Society for Laboratory Automation and Screening (SLAS) 22 Mar 2023

Genetic signature might be shared across multiple substance use disorders, new study reveals

A new study has revealed a common genetic signature that seems to underlie multiple substance use disorders.

22 Mar 2023

New study pinpoints key source of T cell "exhaustion"

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies.

21 Mar 2023

Keck Medicine of USC launches clinical trial investigating innovative procedure to control Type 2 diabetes

More than 37 million Americans have diabetes, and approximately 90-95% have Type 2 diabetes.

21 Mar 2023

Keeping lymph nodes in the body can boost the efficacy of cancer immunotherapy

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

21 Mar 2023

Blunted inflammatory response could make obese patients more susceptible to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

21 Mar 2023

DNA drugs help restore the normal processing of protein-encoding RNA

A protein named TDP-43 has been lost from its normal location in the nucleus of the cell in virtually all persons having amyotrophic lateral sclerosis (ALS) and in up to half of all cases of frontotemporal dementia and Alzheimer’s disease (AD).

From UC San Diego 20 Mar 2023

Perspectives on nucleolar DNA damage response in the fight against cancer

Cancer, which affects so many people each year, relies on proteins to proliferate throughout the body. Scientists are damaging the disease’s protein factories as part of a new tactic to combat the widespread disease.

20 Mar 2023

Novel mechanism by which bacteria colonize the gut identified

A new mechanism by which “good” bacteria colonize the gut was unraveled by scientists at Yale University. The finding could aid spur the development of new probiotic therapies.

20 Mar 2023

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

Cyclic peptides often exhibit low membrane permeability which can be significantly improved via amide-to-ester substitutions-;as demonstrated by researchers from Tokyo Institute of Technology.

20 Mar 2023

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

University of Utah Health scientists have corrected abnormal heart rhythms in mice by restoring healthy levels of a protein that heart cells need to establish connections with one another.

20 Mar 2023

New combination therapy regimen may reduce prostate cancer progression or death by 37%

TALAPRO-2, a study led by Neeraj Agarwal, MD, FASCO, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progression or death by 37%.

20 Mar 2023

Delaying paralysis in ALS by using designer DNA drug

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

20 Mar 2023

Neoadjuvant dual immunotherapy and chemotherapy improve outcomes in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

20 Mar 2023

Previously unknown genetic causes of three rare conditions discovered

Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.

20 Mar 2023

Clinical News and Research

Curcumin could enhance ovarian cancer treatments

Using viruses to fight antibiotic-resistant "superbugs"

How can the adoption of AI technology accelerate drug discovery?

Genetic signature might be shared across multiple substance use disorders, new study reveals

New study pinpoints key source of T cell "exhaustion"

Keck Medicine of USC launches clinical trial investigating innovative procedure to control Type 2 diabetes

Keeping lymph nodes in the body can boost the efficacy of cancer immunotherapy

Blunted inflammatory response could make obese patients more susceptible to severe COVID-19

DNA drugs help restore the normal processing of protein-encoding RNA

Perspectives on nucleolar DNA damage response in the fight against cancer

Novel mechanism by which bacteria colonize the gut identified

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

New combination therapy regimen may reduce prostate cancer progression or death by 37%

Delaying paralysis in ALS by using designer DNA drug

Neoadjuvant dual immunotherapy and chemotherapy improve outcomes in patients with resectable NSCLC

Previously unknown genetic causes of three rare conditions discovered

Researchers discover previously unknown genetic causes of three rare conditions

Common commensal gut bacterium uses phase separation of Rho factor to thrive in the mammalian gut

Fomepizole may reduce disease severity in the lungs of mice with bacterial pneumonia

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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