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Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

Individuals with cocaine use disorder exhibit gene expression changes in two brain regions: the nucleus accumbens, a region associated with reward, and the caudate nucleus, a region mediating habit formation, according to research conducted at the Icahn School of Medicine at Mount Sinai and published February 10 in Science Advances.

13 Feb 2023

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

University of Sydney scientists have discovered a protein in the lung that blocks SARS-CoV-2 infection and forms a natural protective barrier in the human body.

10 Feb 2023

Novel compound curtails influenza virus replication

Viruses use the molecular repertoire of the host cell to replicate. Researchers from the Cluster of Excellence ImmunoSensation2 at the University of Bonn, together with Japanese researchers, want to exploit this for the treatment of influenza.

10 Feb 2023

Novel method enables targeted design of molecules and materials with specific properties

Engineering novel molecules and materials with specific properties can yield significant advances for industrial processes, drug discovery and optoelectronics.

9 Feb 2023

Protein-rich droplets in cells linked to many unresolved diseases

Most proteins localize to distinct protein-rich droplets in cells, also known as "cellular condensates". Such proteins contain sequence features that function as address labels, telling the protein which condensate to move into.

9 Feb 2023

Technology development could help expand usefulness of Raman microscopy

Researchers have developed a Raman microscope that can acquire information hundreds of times faster than a conventional Raman microscope.

8 Feb 2023

Synthetic biosensor could lead to better understanding of cell biology

A synthetic biosensor that mimics properties found in cell membranes and provides an electronic readout of activity could lead to a better understanding of cell biology, development of new drugs, and the creation of sensory organs on a chip capable of detecting chemicals, similar to how noses and tongues work.

8 Feb 2023

New arsenal in the fight against superbugs

RMIT scientists have created a new type of antibiotic that can be rapidly re-engineered to avoid resistance by dangerous superbugs.

8 Feb 2023

Potential approach for mitigating ALS pathogenesis

Every year, 5,000 people in the United States are diagnosed with ALS, an incurable neurodegenerative disease that will destroy them within two to five years.

8 Feb 2023

Promotional spending share allocated to consumer advertising higher for drugs with low added benefit

A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health found that the share of promotional spending allocated to consumer advertising was on average 14.3 percentage points higher for drugs with low added benefit compared to drugs with high added benefit.

8 Feb 2023

Novel combination therapy shows promise in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive form of cancer that originates in the bone marrow, rapidly spreads to the blood and can quickly cause death if not treated promptly.

8 Feb 2023

Study elucidates the structure of centromeric region in chicken cells

The genetic material inside cells is organized into structures called chromosomes. The centromere is essential for the correct division of the chromosomes via interaction with spindle microtubules when cells divide and grow.

7 Feb 2023

Keanumycins: An alternative in the fight against resistant fungi

Pseudomonas bacteria produce a potent antimicrobial natural product, according to scientists at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI).

7 Feb 2023

Study sheds light on why lung tumors do not respond well to immunotherapy

Immunotherapy -; drug treatment that stimulates the immune system to attack tumors -; works well against some types of cancer, but it has shown mixed success against lung cancer.

6 Feb 2023

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

6 Feb 2023

New chemical reaction could transform drug production

Pharmaceutical synthesis is often quite complex; simplifications are needed to speed up the initial phase of drug development and lower the cost of generic production.

3 Feb 2023

Losartan prevents immunotherapy-related edema, improves survival in glioblastoma mouse models

Patients with glioblastoma-;the deadliest type of primary brain tumor-;may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.

3 Feb 2023

Cancer therapies improved by changing an antibody’s binding to a target

Before World Cancer Day (4th February), new research from the Centre for Cancer Immunology at the University of Southampton has demonstrated that altering how firmly an antibody attaches to a target can enhance cancer treatments.

2 Feb 2023

Novel chemical tool reveals how bacteria adapt to the host environment

A research team guided by Professor Xiang David Li of The University of Hong Kong’s (HKU) Department of Chemistry created a new chemical tool to unveil how bacteria adjust to the host environment and control host cells.

1 Feb 2023

Combination of silver nanoparticles and antibiotics effective against antibiotic-resistant bacteria

In a new study, scientists with the University of Florida found that a combination of silver nanoparticles and antibiotics was effective against antibiotic-resistant bacteria.

1 Feb 2023

Drugs News and Research

Research reveals gene expression changes in two brain regions of individuals with cocaine use disorder

A protein in the lung forms a natural protective barrier against SARS-CoV-2 infection

Novel compound curtails influenza virus replication

Novel method enables targeted design of molecules and materials with specific properties

Protein-rich droplets in cells linked to many unresolved diseases

Technology development could help expand usefulness of Raman microscopy

Synthetic biosensor could lead to better understanding of cell biology

New arsenal in the fight against superbugs

Potential approach for mitigating ALS pathogenesis

Promotional spending share allocated to consumer advertising higher for drugs with low added benefit

Novel combination therapy shows promise in acute myeloid leukemia

Study elucidates the structure of centromeric region in chicken cells

Keanumycins: An alternative in the fight against resistant fungi

Study sheds light on why lung tumors do not respond well to immunotherapy

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

New chemical reaction could transform drug production

Losartan prevents immunotherapy-related edema, improves survival in glioblastoma mouse models

Cancer therapies improved by changing an antibody’s binding to a target

Novel chemical tool reveals how bacteria adapt to the host environment

Combination of silver nanoparticles and antibiotics effective against antibiotic-resistant bacteria

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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