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Researchers Develop Synthetic Genes for Self-Assembling Biomaterials

Researchers from the UCLA Samueli School of Engineering and the University of Rome Tor Vergata in Italy have developed synthetic genes that function like the genes in living cells.

5 Nov 2024

APOE4 and Microglia Together Drive Alzheimer's Protein Deposits

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for Alzheimer's disease-;the same cells cause harmful inflammation and clumps of misfolded proteins, according to a new study by scientists at Gladstone Institutes.

5 Nov 2024

Novel Approach to Isolating and Quantifying EV Cargo for Disease Diagnosis

Parkinson's disease (PD) and Alzheimer's disease (AD) are examples of brain illnesses that begin to develop in patients far earlier than the onset of their initial clinical symptoms.

4 Nov 2024

The Role of Neural Crest Stem Cells in Cellular Reprogramming

Researchers at the University of Toronto have identified that neural crest stem cells, a group of cells located in the skin and other parts of the body, are the origin of reprogrammed neurons previously discovered by other scientists.

4 Nov 2024

3D Tumor Microenvironment Model Highlights Role of Ischemia and Acidification in Cancer Spread

Developed 3MIC model simulates tumor microenvironments, enabling direct observation of ischemic effects on cancer cell invasiveness and drug resistance.

4 Nov 2024

Innovative Insights into the Interplay Between Proteins and Small Molecules

With the support of a Maximizing Investigators' Research Award, or MIRA, from the National Institutes of Health, Michigan State University researcher Aleksandra Skirycz is making fundamental discoveries linked to the health and resilience of plants and animals.

4 Nov 2024

ALDH3A2 Enzyme Controls Red-Yellow Pigment Balance in Parrots

A single enzyme fine-tunes red and yellow pigments in parrots' polychromatic plumage, according to a new study. The findings reveal new insights into the molecular mechanisms underlying the evolution and display of color variation in one of nature's most colorful birds. Colors play a central role in ecological adaptation and communication in the natural world.

4 Nov 2024

New Lab-Grown Lip Cells Could Transform Research and Treatment for Disfiguring Lip Conditions

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair effectively. Basic research is essential to improving these treatments, but until now, models using lip cells -; which perform differently to other skin cells -; have not been available.

4 Nov 2024

MicroQuin's Space Research Paves Way for Potential Cancer Treatment

In October, we think pink, and for a good reason—one out of every eight women will be diagnosed with breast cancer in their lifetime, and each year, 2 million women are given this frightening diagnosis.

4 Nov 2024

Immortalized Lip Cells Open Doors for Testing New Therapies

4 Nov 2024

Chloroplast-Infused Cells Revolutionize Tissue Engineering

Recent research from Japan has demonstrated that chloroplasts from algae can be integrated into hamster cells, allowing these cells to perform photosynthesis.

1 Nov 2024

Understanding the Dynamics of Stem Cells

Age influences stem cell survival and immune diversity, according to new research on the long-term dynamics of transplanted stem cells in a patient’s body.

1 Nov 2024

A New Understanding of Viral Infection

Scientists studying animal viruses with the potential to infect humans have discovered a critical protein that could facilitate the spread of a family of organisms known as arteriviruses.

1 Nov 2024

New Discovery Shows TAGLN2 Protein Boosts T Cell Immunity Against Tumors by Enhancing Lipid Metabolism

Findings indicate ovarian cancer disrupts CD8+ T cell metabolism through FABP5 and TAGLN2, suggesting new therapeutic targets for enhancing immune function.

1 Nov 2024

Biologgers Enhance Understanding of Animal Behavior in Nature

Biologgers allow us to see with unprecedented precision how animals move and behave in the wild. But that's only part of the picture, according to a UC Santa Cruz ecologist renowned for using biologging data to tell the deeper story about the lives of marine mammals in a changing world.

1 Nov 2024

Necroptosis Emerges as a Key Target in Alzheimer's Disease

Alzheimer's disease is characterized by a progressive loss of nerve cells leading to a decline in memory and cognition. A team of researchers at KU Leuven and VIB explored the molecular sequence of events in this cellular demise and identified specific inhibitors that could prevent the loss of nerve cells in different mouse models of the disease.

1 Nov 2024

Unraveling the Spatial Complexity of Gene Expression with Seq-Scope

A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024

A New Method to Reprogram Plant Cells Offers Insights into Cell Wall Development

A new method developed by Penn State biologists allows them to turn stripped-down plant cells into other types of cells, similar to the way stem cells differentiate into different cell types. Using this method, the research team explored the banding patterns that increase the stability of plant cell walls -; much like the corrugated patterns in cardboard -; and how they are created.

1 Nov 2024