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Unraveling Lenacapavir's Impact on the HIV Life Cycle

A new anti-retroviral medication for the treatment of human immunodeficiency virus (HIV) infections was licensed by the US Food and Drug Administration and the European Union just over a year ago.

14 Feb 2024

Dr. Bartek Rajwa of Purdue University Named Editor-in-Chief of “Cytometry Part A” Journal by the International Society for Advancement of Cytometry

The International Society for Advancement of Cytometry (ISAC) is pleased to announce the appointment of Dr. Bartek Rajwa as the new Editor-in-Chief of “Cytometry Part A – the Journal of Quantitative Cell Science.”

10 Feb 2024

Aspen Biosciences Launches Pipeline, The Program Management Software Platform Specifically for Drug Discovery. The Groundbreaking ‘Pipeline’ Platform is Now Available for Therapeutics Development Teams

Aspen Biosciences, a leading provider of custom software, and integrations for drug discovery companies, is excited to announce the launch of Pipeline, the drug discovery program management software platform.

8 Feb 2024

From Lab Trials to Clinical Studies - Integrin αV's Role in Cancer Prognosis

Researchers at City of Hope, one of the biggest cancer research and treatment centers in the US, have identified a novel biological process that is critical to the pathogenic potential of cancer cells.

6 Feb 2024

Decoding Virus-Host Tug-of-War with RNA-Protein Interaction Mapping

The interplay between ribonucleic acid (RNA) and proteins is not only important for maintaining cellular homeostasis but is also at the center of the tug-of-war between virus and host.

2 Feb 2024

Chemists Develop Two-Step Method to Create Promising Molecules for Life Sciences Research

Organic compounds in the field of chemistry range from simple hydrocarbons to complex molecules, with diverse functional groups added to the main carbon backbone.

30 Jan 2024

New Horizons in Chemical Biology: A Novel Approach to Synthesize Dibenzothiophene S-Oxides

Dibenzothiophene S-oxides are important in various biochemical processes. However, their synthesis using conventional methods is not easy.

30 Jan 2024

Revolutionizing Drug Discovery with Novel Sulfur Compound Synthesis

Over the past decade, there has been significant progress in the development of novel sulfur-containing compounds utilized across diverse industries, including pharmaceuticals and agricultural products.

23 Jan 2024

Traffic Jam in the Brain: Study Uncovers Cellular Cause of Rare Neurological Disease

Researchers from McGill University, led by Professor Alanna Watt of the Department of Biology, have identified previously unknown changes in brain cells affected by a neurological disease.

22 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024

National Korea Maritime and Ocean University Researchers Explore the Impact of Microplastics and Toxin Exposure on Goldfish

Microplastic particles can travel long distances in oceans and are known to carry with them harmful and persistent organic pollutants like benzo[α]pyrene (BaP), a polycyclic aromatic hydrocarbon.

11 Jan 2024

Scientists Reinvent Spectinomycin as a Powerhouse Weapon for Drug-Resistant Superbug

Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance.

10 Jan 2024

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

A new study published in Nature Cell Biology by Mark Alkema, PhD, professor of neurobiology, establishes an important molecular link between specific B12-producing bacteria in the gut of the roundworm C. elegans and the production of acetylcholine, a neurotransmitter important to memory and cognitive function.

5 Jan 2024

Breakthrough in Synthetic Biology: Researchers Build Artificial CO2-Fixing Pathway

Synthetic biology offers the opportunity to build biochemical pathways for the capture and conversion of carbon dioxide (CO2).

3 Jan 2024

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.

26 Dec 2023

Simultaneous Production of Bioplastics and High-Value Carotenoids by Multifunctional Bacteria

We often look to the smallest lifeforms for help solving the biggest problems: Microbes help make foods and beverages, cure diseases, treat waste and even clean up pollution.

26 Dec 2023

Fox Urine Compound Activates Multiple Sensory Pathways for Robust Insect Avoidance

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

26 Dec 2023

NTNU Develops Dual-Mechanism Antibiotic Strategy to Combat Antimicrobial Resistance

NTNU has developed a promising antibiotic candidate against MRSA. Behind the discovery lies a methodology that may be important in the fight against antimicrobial resistance.

18 Dec 2023

Cryo-EM Analysis Uncovers Unexpected Enzymatic Switch in Bacterial Anti-Phage System

Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.

14 Dec 2023

Mucus Thickness Dictates Bacterial Behavior, Affecting Infection Potential

The telltale signs of cold and flu season—sniffles, snorts, and the sound of noses being blown—serve as indicators of increased mucus production.

6 Dec 2023

Compound News and Research

Unraveling Lenacapavir's Impact on the HIV Life Cycle

Dr. Bartek Rajwa of Purdue University Named Editor-in-Chief of “Cytometry Part A” Journal by the International Society for Advancement of Cytometry

Aspen Biosciences Launches Pipeline, The Program Management Software Platform Specifically for Drug Discovery. The Groundbreaking ‘Pipeline’ Platform is Now Available for Therapeutics Development Teams

From Lab Trials to Clinical Studies - Integrin αV's Role in Cancer Prognosis

Decoding Virus-Host Tug-of-War with RNA-Protein Interaction Mapping

Chemists Develop Two-Step Method to Create Promising Molecules for Life Sciences Research

New Horizons in Chemical Biology: A Novel Approach to Synthesize Dibenzothiophene S-Oxides

Revolutionizing Drug Discovery with Novel Sulfur Compound Synthesis

Traffic Jam in the Brain: Study Uncovers Cellular Cause of Rare Neurological Disease

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

National Korea Maritime and Ocean University Researchers Explore the Impact of Microplastics and Toxin Exposure on Goldfish

Scientists Reinvent Spectinomycin as a Powerhouse Weapon for Drug-Resistant Superbug

B12-Producing Gut Bacteria Modulate Neurotransmitter Levels and Reduce Seizures in C. elegans

Breakthrough in Synthetic Biology: Researchers Build Artificial CO2-Fixing Pathway

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Simultaneous Production of Bioplastics and High-Value Carotenoids by Multifunctional Bacteria

Fox Urine Compound Activates Multiple Sensory Pathways for Robust Insect Avoidance

NTNU Develops Dual-Mechanism Antibiotic Strategy to Combat Antimicrobial Resistance

Cryo-EM Analysis Uncovers Unexpected Enzymatic Switch in Bacterial Anti-Phage System

Mucus Thickness Dictates Bacterial Behavior, Affecting Infection Potential

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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