Dopamine News and Research

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Dopamine is a hormone and neurotransmitter occurring in a wide variety of animals, including both vertebrates and invertebrates. In the brain, this phenethylamine functions as a neurotransmitter, activating the five types of dopamine receptors — D1, D2, D3, D4 and D5, and their variants. Dopamine is produced in several areas of the brain, including the substantia nigra and the ventral tegmental area. Dopamine is also a neurohormone released by the hypothalamus. Its main function as a hormone is to inhibit the release of prolactin from the anterior lobe of the pituitary. Dopamine has many functions in the brain, including important roles in behavior and cognition, motor activity, motivation and reward, inhibition of prolactin production (involved in lactation), sleep, mood, attention, and learning. Dopaminergic neurons (i.e., neurons whose primary neurotransmitter is dopamine) are present chiefly in the ventral tegmental area (VTA) of the midbrain, substantia nigra pars compacta, and arcuate nucleus of the hypothalamus.
Solving A Parkinson's Disease Puzzle Through Protein Design

Solving A Parkinson's Disease Puzzle Through Protein Design

New protein design could help in drug discovery for Parkinson’s disease

New protein design could help in drug discovery for Parkinson’s disease

Study reveals structure of an activated dopamine receptor

Study reveals structure of an activated dopamine receptor

Mice study reveals new therapeutic strategy for slowing down Huntington's disease

Mice study reveals new therapeutic strategy for slowing down Huntington's disease

Synthetic molecule suppresses drug cravings with fewer side effects

Synthetic molecule suppresses drug cravings with fewer side effects

Making opioids safer and more effective

Making opioids safer and more effective

Autoimmunity Plays A Role In Parkinson's Disease

Autoimmunity Plays A Role In Parkinson's Disease

Study finds how sweet taste perception is fine-tuned in response to different diets

Study finds how sweet taste perception is fine-tuned in response to different diets

Researchers engineer skin cells into brain cells for effective regenerative therapies

Researchers engineer skin cells into brain cells for effective regenerative therapies

Parallel neural pathways bypassing brain’s frequency control enable animals to move faster

Parallel neural pathways bypassing brain’s frequency control enable animals to move faster

Researchers successfully crystallize and map novel conformation of LeuT transporter

Researchers successfully crystallize and map novel conformation of LeuT transporter

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