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Artificial Intelligence Designs Novel DNA Elements for Precise Gene Control

Using artificial intelligence, scientists at Yale University, the Broad Institute of MIT and Harvard, and The Jackson Laboratory have created thousands of novel DNA switches that can precisely regulate a gene's expression in many cell types.

24 Oct 2024

Simple Neural Circuit Controls Chewing and Appetite

Speaking, singing, coughing, laughing, yelling, yawning, chewing-;we use our jaws for many purposes. Each action requires a complex coordination of muscles whose activity is managed by neurons in the brain.

24 Oct 2024

Personalized Mini-Brains Provide Insight into Autism Spectrum Disorder

Using stem cells generated from patients with a rare and severe form of autism spectrum disorder and intellectual disability, Scripps Research scientists have grown personalized "mini-brains" (or organoids) to study the disorder in new detail.

24 Oct 2024

New Bacterial Toxins Discovered as Potential Weapons Against Infections

Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections.

23 Oct 2024

Unraveling the Mechanics Behind Transcription-Dependent Motions of Single Genes

A group of researchers has found unexpected links between genome packing, gene activity, and genome-wide motions, exposing features of the genome's structure that have a direct impact on gene expression and regulation.

23 Oct 2024

New Study Uncovers How Viral Infections Trigger Pain, Identifies Potential Target for Relief

Findings indicate nociceptors detect viral nucleic acids, activating STING and TRPV1, highlighting new pain mechanisms in viral infections like HSV-1.

23 Oct 2024

Unraveling the Genetic Blueprint of the Deep Brain

Researchers have discovered 254 genetic variations that influence important “deep brain” structures, such as those that govern memory, motor skills, addictive behaviors, and more, in one of the biggest-ever investigations of DNA and brain volume.

22 Oct 2024

Study Identifies Novel Chromatin Configuration in Turtle Genomes

Researchers from UAB and Iowa State University have produced the first-ever genome assemblies of two hidden-neck turtle species.

22 Oct 2024

Genetic Study Offers Hope for the Endangered Oriental Stork

A new genomic study of the endangered Oriental Stork reveals that the population's genetic health is still surprisingly strong, with high genetic diversity and low levels of inbreeding.

22 Oct 2024

Mapping Auxiliary Metabolic Genes in Ocean Viruses

The microbes that cycle nutrients in the ocean don't do the work on their own – the viruses that infect them also influence the process.

21 Oct 2024

Researchers Discover GAME15's Role in Steroidal Compound Biosynthesis

Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum.

21 Oct 2024

Discovering the Molecular Mechanisms Behind Chicken Feather Patterns

Birds possess unique skin appendages called feathers that are derived from the outermost layer of skin cells. Feathers are important for several functions, such as flight, temperature regulation, protection from external stimuli, and mating behavior.

21 Oct 2024

Researchers Unravel Plant-to-Fungi Communication Using Baker's Yeast

Researchers at the University of Toronto have cracked the code of plant-to-fungi communication in a new study published in the journal Molecular Cell.

18 Oct 2024

Disinfectants Foster the Growth of Novel Microbial Strains in Urban Settings

A recent study in the journal Microbiome has uncovered new strains of microbes that have evolved to utilize the scarce resources found in cities, revealing that daily habits are altering the composition of microorganisms in indoor environments.

18 Oct 2024

Research Advances Understanding of Gene Expression Mechanisms

During embryonic development, cells start out as pluripotent, or have the potential to become many different cell types through differentiation.

17 Oct 2024

New Insights into Nager Syndrome Through Zebrafish Models

Nager syndrome, or NS, is a rare genetic disease that affects the development of the face and limbs, usually causing anomalies in the bone structures of the jaws, cheeks, and hands.

17 Oct 2024

Study Unlocks Mechanisms Behind Nucleosome Arrays Using Signal Theory and Machine Learning

Findings show that machine learning can accurately predict nucleosome positions, emphasizing the relationship between nucleosome architecture and gene activity.

17 Oct 2024

Fly Hormone Discovery Sheds Light on Lifespan Regulation and Aging

Researchers at Brown University have found that a neuropeptide hormone produced in the gut of flies influences their lifespan.

17 Oct 2024

Unveiling the Potential of YY1 in Blood Cell Development and Therapy

Common lymphoid progenitors, pre-pro-B cells, pro-B cells, pre-B cells, immature B cells, and finally more mature and specialized B cells are the stages in which B cells, white blood cells that produce antibodies, develop.

17 Oct 2024

Transposable Elements Drive a Critical Transition in Early Embryogenesis

Researchers at Sinai Health have discovered that DNA elements known as transposons, which may travel throughout the genome, control a crucial stage in early human development instead of human genes.

16 Oct 2024