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Achieving 3D Printing Inside 'Mini-Organs' Growing in Hydrogels

Scientists from the NIHR Great Ormond Street Hospital Biomedical Research Centre (a collaboration between GOSH and UCL), London, and University of Padova, Italy, have shown for the first time how 3D printing can be achieved inside 'mini-organs' growing in hydrogels -- controlling their shape, activity, and even forcing tissue to grow into 'molds.'

12 Jun 2023

Researchers Discover Novel Combination Therapy to Counter Antibiotic-resistant Mycobacterium Abscessus Infections

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with Nanyang Technological University Singapore (NTU Singapore) and National University Hospital (NUH), have discovered a novel therapy by combining two antibiotics, rifaximin and clarithromycin, to treat Mycobacterium abscessus (M. abscessus), a non-tuberculous mycobacterium (NTM) that causes chronic lung-related infections.

9 Jun 2023

Scientists Discover a New Step in the Differentiation of Precursor Cells Into Mature Basophils

Big changes often happen in small steps, and it's not always easy to see how we get from point A to point B.

8 Jun 2023

Study Reveals Mechanisms Behind Swallowing in Detail

Sensory cells in the vagus nerve can detect and locate food in the esophagus. Their signals help transport the food onward to the stomach. Signal failure leads to swallowing disorders, say a team led by Carmen Birchmeier at the Max Delbrück Center.

29 May 2023

Climate Change is Altering Hibernation Patterns of Arctic Ground Squirrels

Arctic ground squirrels are unique among mammals. Their ability to keep from freezing even when body temperatures dip below that mark on the thermometer enables them to survive extreme winter climates.

26 May 2023

Study Characterizes the Properties of MAIT Cells in Mouse Lung

A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike.

26 May 2023

Scarring on the Extracellular Matrix Causes Muscles to Stop Working in Duchenne Muscular Dystrophy

Muscles that ache after a hard workout usually don't hurt for long, thanks to stem cells that rush to the injured site along "collagen highways" within the muscle and repair the damaged tissue.

12 May 2023

Research Helps Better Understand How Developing Cells Break Free From Their Tissue of Origin

Cancer's ability to spread throughout the body -; a process known as metastasis -; is responsible for the vast majority of cancer deaths.

11 May 2023

Mutant MRTFB Proteins Associated With Novel Neurodevelopmental Disorder

Researchers at Baylor College of Medicine have linked specific variants or mutations of the gene myocardin-related transcription factor B (MRTFB) with a novel neurodevelopmental disorder.

10 May 2023

Study Reveals an Immunological Strategy to Overcome Microbiome-Related Immunotherapy Resistance

Cancer immunotherapy has transformed the treatment of many types of cancer. Yet, for reasons that remain poorly understood, not all patients get the same benefit from these powerful therapies.

4 May 2023

Diet Plays a Bigger Role in Shaping Intestinal Microbiota Composition Than Defensins

Researchers at Umeå University, Sweden, have found that among the many factors that shape the intestinal microbiota composition, diet has a much stronger impact than defensins, which are intestinal defence molecules produced by the body.

4 May 2023

Occludin Protein Plays a Critical Role in Cell-to-Cell Transmission of SARS-CoV-2 Virus

While the coronavirus continues to infect people around the world, researchers at the University of Missouri have identified a specific protein inside the human body that plays a critical role in how the virus spreads from cell to cell after infection -; a discovery that will help better understand the COVID-19 disease and could lead to the development of new antiviral drugs in the future.

2 May 2023

Understanding the Origins of Human Disease Using the Power of Evolutionary Genomics

Hundreds of scientific studies have been conducted over the years to find the genes underlying common human traits, from eye color to intelligence and physical and mental illnesses.

28 Apr 2023

Some Promising Human Antibodies can Fight New Variants of SARS-CoV-2

An anonymous San Diego resident has become a fascinating example of how the human immune system fights SARS-CoV-2.

27 Apr 2023

Capturing Viruses in a Lipid Trap

Viruses like influenza A and Ebola invade human cells in a number of steps. In an interdisciplinary approach, research teams from Heidelberg University and Heidelberg University Hospital investigated the final stages of viral penetration using electron tomography and computer simulations.

26 Apr 2023

Researchers Reveal Dual Nature of Beneficial Bacteria UD1022

Alfalfa, also known in Latin as Medicago sativa, is an agricultural crop that is part of the legume family. It is known as a protein-rich food source for dairy cattle that is easily digested and can lead to increased milk production.

19 Apr 2023

The Implications of Biological Clock on Lung Health

The body’s biological clock is interfered with by abnormal sleep habits, such as those of night shift workers, which have been connected to lung health problems.

18 Apr 2023

Deletion of Specific Protein Creates a Hostile Environment for Aggressive Breast Tumors

Scientists at VCU Massey Cancer Center discovered that the deletion of a specific protein creates a hostile environment for tumor cells and significantly subdues breast cancer growth and spread.

13 Apr 2023

New Device Enables Construction of Complex 3D Organoids Without Using Elaborate Techniques

A team led by Masaya Hagiwara of RIKEN national science institute in Japan has developed an ingenious device, using layers of hydrogels in a cube-like structure, that allows researchers to construct complex 3D organoids without using elaborate techniques.

10 Apr 2023

Researchers Identify Antibody that may Block Infection by All Dominant SARS-CoV-2 Variants

A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent.