Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Cryo-EM Technology Paves the Way for Major Biological Discovery

Ben Orlando's research talk at MSU's Department of Biochemistry and Molecular Biology in 2019 laid the groundwork for a team effort that had been developing for decades.

25 Oct 2024

New Insights into How TRIM25 Fights RNA Viruses

Human bodies are attacked every single second of every day. The invading agents include bacteria, viruses, parasites, and toxins both living and non-living things that could impair how well bodies work.

25 Oct 2024

New Study Links Cannabis Use to DNA Methylation Changes in Mental Health Pathways

Research reveals that frequent high-potency cannabis use alters DNA methylation, affecting mitochondrial and immune genes, with implications for mental health.

25 Oct 2024

Light-Activated Immune Therapy Shows Promise Against Solid Tumors

Immunotherapies that mobilize a patient's own immune system to fight cancer have become a treatment pillar.

25 Oct 2024

AI Model Predicts Active Ingredients with Dual Target Properties

Researchers from the University of Bonn have trained an AI process to predict potential active ingredients with special properties.

25 Oct 2024

Understanding Algal Gene Expression Through Histone Dynamics

A previously unknown molecular signature of the regulation of algal genomes during the cell cycle was discovered, thanks to a novel technique that research teams can employ to test and compare various protein forms and protein complexes.

24 Oct 2024

Artificial Intelligence Designs Novel DNA Elements for Precise Gene Control

Using artificial intelligence, scientists at Yale University, the Broad Institute of MIT and Harvard, and The Jackson Laboratory have created thousands of novel DNA switches that can precisely regulate a gene's expression in many cell types.

24 Oct 2024

Researchers Identify Mechanism of Immune Suppression in Ovarian Cancer

Researchers at Weill Cornell Medicine have shown that ovarian cancers disable immune cells and prevent them from attacking by cutting off the energy source that T cells rely on.

24 Oct 2024

Personalized Mini-Brains Provide Insight into Autism Spectrum Disorder

Using stem cells generated from patients with a rare and severe form of autism spectrum disorder and intellectual disability, Scripps Research scientists have grown personalized "mini-brains" (or organoids) to study the disorder in new detail.

24 Oct 2024

Discovery of RNA Brake Offers Insights into Neurodevelopmental Disorders

When a gene produces too much protein, it can have devastating consequences on brain development and function.

24 Oct 2024

Study Uncovers Mechanism Behind B-Cell Maturation in Leukemia

Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic Leukaemia (B-ALL) next year in Spain, according to the latest projections from the Spanish network of cancer registries (REDECAN).

23 Oct 2024

New Insights into SARS-CoV-2’s Evasion of Innate Immunity

The novel coronavirus SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses.

23 Oct 2024

New Bacterial Toxins Discovered as Potential Weapons Against Infections

Researchers have discovered a new group of bacterial toxins that can kill harmful bacteria and fungi, opening the door to potential new treatments for infections.

23 Oct 2024

Structural Insights into Bacteriophages Open Doors for New Therapeutics

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

23 Oct 2024

New Study Uncovers How Viral Infections Trigger Pain, Identifies Potential Target for Relief

Findings indicate nociceptors detect viral nucleic acids, activating STING and TRPV1, highlighting new pain mechanisms in viral infections like HSV-1.

23 Oct 2024

Phages Form Unique 3D Shapes, Boosting Disease Detection

While preparing slides to be examined under a powerful microscope, a team of McMaster researchers who frequently work with bacteriophage viruses that consume bacteria had a pleasant and potentially very significant surprise.

22 Oct 2024

Unlocking the Secrets of Life Through Synthetic Biology

It is one of the most fundamental questions in science: how can lifeless molecules come together to form a living cell? Bert Poolman, Professor of Biochemistry at the University of Groningen, has been working on this problem for over twenty years.

22 Oct 2024

How Cancer Cells Use Ribosomes to Evade the Immune System

The protein factories of our cells are much more diverse than we thought they were. Scientists from the Netherlands Cancer Institute have now shown that cancer cells can use these so-called ribosomes to boost their invisibility cloak, helping them hide from the immune system.

22 Oct 2024

Advancements in Understanding Intestinal Hormone Secretion

A multi-institutional group of researchers led by the Hubrecht Institute and Roche's Institute of Human Biology has developed strategies to identify regulators of intestinal hormone secretion.

21 Oct 2024

Researchers Discover GAME15's Role in Steroidal Compound Biosynthesis

Researchers at the Max Planck Institute for Chemical Ecology have identified GAME15 as a key protein that regulates the biosynthesis of both steroidal glycoalkaloids and steroidal saponins in plants of the genus Solanum.

21 Oct 2024